Postdoctoral Research Associate in Enteroendocrine Electrophysiology, Wellcome Trust-MRC Institute of Metabolic Science

Job ID: 4712
Job date: 2015-11-10
End Date:

Company : University of Cambridge 

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Role : Student 


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Job Description:
Postdoctoral Research Associate in Enteroendocrine Electrophysiology, Wellcome Trust-MRC Institute of Metabolic Science University of Cambridge - Clinical Biochemistry Location: Cambridge Salary: £28,695 to £37,394 Hours: Full Time Contract Type: Contract / Temporary Placed on: 10th November 2015 Closes: 9th December 2015 Job Ref: RG07547 ★ View Employer Profile

A post-doctoral research associate position is available in the group of Prof Fiona Gribble and Dr Frank Reimann at the Institute of Metabolic Science, University of Cambridge. The position is funded by the Wellcome Trust, and has a focus on improving understanding the role of the gut-pancreatic-brain axis in obesity and related metabolic diseases.

You will run a program of research to investigate nutrient sensing and intracellular signalling pathways in the enteroendocrine axis, using cell lines, primary intestinal/neuronal cultures and tissue slices/whole mounts. You will be required to use patch clamp electrophysiology for recording from enteroendocrine cells and target neuronal populations, and live cell imaging techniques including confocal microscopy for monitoring cellular signalling events.  The successful applicant will develop the research objectives and assist in preparation of proposals and application to funding bodies. An important part of the role will be analysis of data, the presentation of research work and data within the Institute, nationally and internationally and the preparation and submission of research for publication in peer-reviewed journals.  You will also assist in providing instruction to graduate students and other members of the research group in the use of specialist cellular imaging and electrophysiological techniques. 

Applicants must possess:

A PhD in biochemistry, cell biology, physiology or a related biological sciences discipline. Extensive practical expertise in the use of patch clamp electrophysiology and real-time single cell imaging of intracellular signalling pathways. Research experience in G-protein coupled receptor physiology. Practical experience in working with cell lines, primary intestinal and neuronal cell cultures and tissue slices. Evidence of ability to work as part of a research team and to organise and participate in collaborative research initiatives and projects. Significant and demonstrable experience in dealing with data acquisition and analysis protocols in the field of cellular signalling. Evidence of ability to prepare and analyse data for publication in scientific journals and to present scientific data to peers in seminars and at conferences. Evidence of ability to impart knowledge and skills to other members of the research group

Fixed-term: The funds for this post are available for 24 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment. This appointment also requires a Research Passport application.

To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/8622. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Informal enquiries can be made to Professor Fiona Gribble, Metabolic Research Laboratories, Level 4, Wellcome Trust-MRC Institute of Metabolic Science, Box 289 Addenbrooke's Hospital, Cambridge CB2 0QQ.  Email: fmg23@cam.ac.uk

Please quote reference RG07547 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.


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