Job ID: 3298
Job date: 2015-04-29
End Date:
Company : University College London Country : Role : Postdoc
Job date: 2015-04-29
End Date:
Company : University College London Country : Role : Postdoc
Job Description:
Postdoctoral Training Fellowship - Synthetic Biology: Reverse Engineering the Cytoskeleton The Francis Crick Institute Location: London Salary: £33,500 to £36,500 per annum Hours: Full Time Contract Type: Permanent Placed on: 29th April 2015 Closes: 27th May 2015 Job Ref: 297
This is a full-time, fixed term position of 4 years on Crick Terms and Conditions of Employment.
The Francis Crick institute (the Crick) is a partnership between the Medical Research Council (MRC), Cancer Research UK (CRUK), the Wellcome Trust, University College London (UCL), Imperial College London and Kings College London. It is a registered charity whose purpose is to conduct biomedical research into all aspects of human health and disease.
The institute will be a world-leading centre of biomedical research and innovation. It will promote connections between researchers and disciplines and between academic institutions, healthcare organisations and businesses. Dedicated to research excellence, the institute will have the scale, vision and expertise to tackle the most challenging scientific questions underpinning health and disease. Due to open in November 2015, The Crick will be located in a new, purpose built research centre in central London (Brill Place next to St. Pancras International) and will house some 1,250 researchers and 250 support staff.
The position of Postdoctoral Training Fellow in Synthetic Biology: Reverse Engineering the Cytoskeleton has been created to contribute towards ERC-funded research using synthetic in vitro reconstitution and microfluidics approaches to understand cytoskeleton function.
Lab Webpage: https://www.crick.ac.uk/research/a-z-researchers/researchers-p-s/thomas-surrey/
Organisation: The post holder will be a member of the laboratory on 'Synthetic and systems biochemistry of the microtubule cytoskeleton' led by Thomas Surrey.
Objectives: The research aims to understand the design principles of the self-organising microtubule cytoskeleton. In this project, microfluidic control will be essential to perform biochemical reactions in controlled micro-environments such as droplets and liposomes to mimic cellular constraints imposed on cytoskeleton morphology by the plasma membrane.
Specific objectives will include, but not limited to:
Develop microfluidic tools for controlled mixing of protein solutions and for the preparation of liposomes Develop miniaturised assays for the fluorescence microscopy-based observation of self-organising biochemical systems in vitro mimicking natural cytoskeleton architecture and function
Person Specification: The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegiate, in addition to the following:
Essential
A PhD or in final stages of completing a PhD in biophysics, bioengineering, biochemistry or related field. Extensive expertise in microfluidics Basic knowledge of molecular biology and protein biochemistry At least one first authorship in a peer-reviewed international publication Ability to work independently, creativity and good communication skills.
Desirable
Experience with fluorescence microscopy Experience with surface chemistry Good understanding of membrane and cytoskeleton biochemistry/biophysics
References
Baumann & Surrey, J Biol Chem 289, 2254, 2014 Dogterom & Surrey, Curr Op Cell Biol 25, 1, 2012 Bieling et al., Cell, 142, 420, 2010 Hentrich & Surrey, J Chem Biol 189, 465, 2010 Surrey, Nedelec et al., Science 292, 1167, 2001
If you are interested in applying for this role, please send your CV and covering letter, explaining your motivation and suitability for this role including details of your current salary, to Thomas Surrey via jobs@crick.ac.uk quoting ‘Postdoctoral Training Fellow – Synthetic Biology – Ref 297’ in the subject line.
The closing date for applications is 27 May 2015 at 5pm.
For any questions relating to this role, please contact either Nicola Howes, Research Administrator via Nicola.Howes@crick.ac.uk or Nicola Texeira, Resourcing Advisor via jobs@crick.ac.uk
Additional Info:
[Click Here to Access the Original Job Post]
Postdoctoral Training Fellowship - Synthetic Biology: Reverse Engineering the Cytoskeleton The Francis Crick Institute Location: London Salary: £33,500 to £36,500 per annum Hours: Full Time Contract Type: Permanent Placed on: 29th April 2015 Closes: 27th May 2015 Job Ref: 297
This is a full-time, fixed term position of 4 years on Crick Terms and Conditions of Employment.
The Francis Crick institute (the Crick) is a partnership between the Medical Research Council (MRC), Cancer Research UK (CRUK), the Wellcome Trust, University College London (UCL), Imperial College London and Kings College London. It is a registered charity whose purpose is to conduct biomedical research into all aspects of human health and disease.
The institute will be a world-leading centre of biomedical research and innovation. It will promote connections between researchers and disciplines and between academic institutions, healthcare organisations and businesses. Dedicated to research excellence, the institute will have the scale, vision and expertise to tackle the most challenging scientific questions underpinning health and disease. Due to open in November 2015, The Crick will be located in a new, purpose built research centre in central London (Brill Place next to St. Pancras International) and will house some 1,250 researchers and 250 support staff.
The position of Postdoctoral Training Fellow in Synthetic Biology: Reverse Engineering the Cytoskeleton has been created to contribute towards ERC-funded research using synthetic in vitro reconstitution and microfluidics approaches to understand cytoskeleton function.
Lab Webpage: https://www.crick.ac.uk/research/a-z-researchers/researchers-p-s/thomas-surrey/
Organisation: The post holder will be a member of the laboratory on 'Synthetic and systems biochemistry of the microtubule cytoskeleton' led by Thomas Surrey.
Objectives: The research aims to understand the design principles of the self-organising microtubule cytoskeleton. In this project, microfluidic control will be essential to perform biochemical reactions in controlled micro-environments such as droplets and liposomes to mimic cellular constraints imposed on cytoskeleton morphology by the plasma membrane.
Specific objectives will include, but not limited to:
Develop microfluidic tools for controlled mixing of protein solutions and for the preparation of liposomes Develop miniaturised assays for the fluorescence microscopy-based observation of self-organising biochemical systems in vitro mimicking natural cytoskeleton architecture and function
Person Specification: The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegiate, in addition to the following:
Essential
A PhD or in final stages of completing a PhD in biophysics, bioengineering, biochemistry or related field. Extensive expertise in microfluidics Basic knowledge of molecular biology and protein biochemistry At least one first authorship in a peer-reviewed international publication Ability to work independently, creativity and good communication skills.
Desirable
Experience with fluorescence microscopy Experience with surface chemistry Good understanding of membrane and cytoskeleton biochemistry/biophysics
References
Baumann & Surrey, J Biol Chem 289, 2254, 2014 Dogterom & Surrey, Curr Op Cell Biol 25, 1, 2012 Bieling et al., Cell, 142, 420, 2010 Hentrich & Surrey, J Chem Biol 189, 465, 2010 Surrey, Nedelec et al., Science 292, 1167, 2001
If you are interested in applying for this role, please send your CV and covering letter, explaining your motivation and suitability for this role including details of your current salary, to Thomas Surrey via jobs@crick.ac.uk quoting ‘Postdoctoral Training Fellow – Synthetic Biology – Ref 297’ in the subject line.
The closing date for applications is 27 May 2015 at 5pm.
For any questions relating to this role, please contact either Nicola Howes, Research Administrator via Nicola.Howes@crick.ac.uk or Nicola Texeira, Resourcing Advisor via jobs@crick.ac.uk
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]