Job Description:
The person in this position will work as part of the Molecular, Expression and Screening Technologies (MEST) Group within Sanofi’s rapidly expanding North America R&D Biologics Research organization. The successful candidate will draw on their laboratory experience to proactively create enabling software tools applicable to the following laboratory and information workflows: antibody discovery (hybridoma, phage / yeast / mammalian display, single B-cell cloning); molecular biology; protein engineering; protein expression and purification; protein analytics; data mining; data management. The scientist will be comfortable being part of a team having the remit to manage and maintain the group informatics workflow and registration system (Genedata Biologics), ensuring coordination between Sanofi’s global research hubs in Boston, Paris and Frankfurt. Key to the role is the ability to proactively identify opportunities to enhance the scientist’s interaction with the system (input / querying / reporting) and contributing to ongoing efforts to integrate the system with other systems in the R&D application landscape. Additionally, this person will support the establishment and ongoing maintenance of locally installed custom automation platforms for high-throughput plasmid construct design and generation and high-throughput protein expression and purification. This person must have a broad appreciation of the early stage biologic/antibody drug discovery process with relevant laboratory experience as well as demonstrable informatics skills. The scientist in this position must have the ability to troubleshoot and resolve problems in which initiative and judgment are required; the ability to work in a fast-paced environment while maintaining a high level of attention to detail; the ability to organize and present data; the ability to work in a collaborative team environment and to communicate effectively both within the immediate group and across groups.
Additional Info:
#LI-SA Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Sanofi, Empowering Life[Click Here to Access the Original Job Post]
The person in this position will work as part of the Molecular, Expression and Screening Technologies (MEST) Group within Sanofi’s rapidly expanding North America R&D Biologics Research organization. The successful candidate will draw on their laboratory experience to proactively create enabling software tools applicable to the following laboratory and information workflows: antibody discovery (hybridoma, phage / yeast / mammalian display, single B-cell cloning); molecular biology; protein engineering; protein expression and purification; protein analytics; data mining; data management. The scientist will be comfortable being part of a team having the remit to manage and maintain the group informatics workflow and registration system (Genedata Biologics), ensuring coordination between Sanofi’s global research hubs in Boston, Paris and Frankfurt. Key to the role is the ability to proactively identify opportunities to enhance the scientist’s interaction with the system (input / querying / reporting) and contributing to ongoing efforts to integrate the system with other systems in the R&D application landscape. Additionally, this person will support the establishment and ongoing maintenance of locally installed custom automation platforms for high-throughput plasmid construct design and generation and high-throughput protein expression and purification. This person must have a broad appreciation of the early stage biologic/antibody drug discovery process with relevant laboratory experience as well as demonstrable informatics skills. The scientist in this position must have the ability to troubleshoot and resolve problems in which initiative and judgment are required; the ability to work in a fast-paced environment while maintaining a high level of attention to detail; the ability to organize and present data; the ability to work in a collaborative team environment and to communicate effectively both within the immediate group and across groups.
Knowledge and Skills:
Required:- Laboratory experience in life sciences with a clear understanding in assay execution workflows – preferably in a biopharm / biotech setting
- Ability to transform and analyze data through a variety of methods.
- Comfort with basic scripting to support scientific analysis and workflow enablement
- Ability to work with LIMS (Laboratory Information Management System) and biological registration systems (eg: Genedata Biologics)
- Experience with antibody sequence analysis and the design of multi-specific antibody constructs.
- Experience with pipelining software ( eg Pipeline Pilot / KNIME)
- Experience with scientific analysis and BI software packages (eg GraphPad / Activity Base / Genedata Screener /Spotfire / Tableau)
- Object orientated programming (eg Python, Java)
- SQL and relational databases
- Machine Learning (eg TensorFlow)
- Experience with B-cell cloning / NGS / microfluidics
- Experience in running automation and high throughput instrumentation including liquid handlers (Tecan/Hamilton)
Requeriments :
Skills :
- Biology
- LIMS
- Machine Learning
- Next Generation Sequencing
- Programing in Python
- Programing Skills
- Programming in Java
- SQL
Areas :
Additional Info:
#LI-SA Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Sanofi, Empowering Life[Click Here to Access the Original Job Post]