Job ID: 568039
Job date: 2016-01-18
End Date:
Company : Celgene Corporation Country : Role : Research Scientist
Job date: 2016-01-18
End Date:
Company : Celgene Corporation Country : Role : Research Scientist
Job Description:
Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture. Overview We seek a talented, collaborative inter-disciplinary scientist to lead work on the computational analysis of high-dimensional tissue, cell and molecular profiling data. This individual will play a key scientific role leveraging innovative computational analysis strategies and rich patient data to empower data-driven decisions for therapeutic programs in Celgene’s Epigenetics Thematic Center of Excellence (TCoE). The role will align directly with the Celgene mission to improve therapeutic outcomes in complex diseases of unmet medical need. Applications range from providing deep insight into therapeutic mechanisms of action for both existing and novel therapies, to the identification of novel targets and prediction of patient phenotypes associated with response to therapy. Analysis scenarios involve data from epigenomic, transcriptomic, proteomic, genomic, and wider cell-molecular profiling platforms. Expertise in the analysis and interpretation of next-generation sequencing data is prerequisite. The position would suit an individual with strong scientific leadership potential and excellent communication and collaboration skills. Applications are encouraged from those looking to bridge the gap between academic and industrial research environments to impact delivery of truly innovative and life-changing therapies. Strong interest in the inter-disciplinary application of computational analysis methods to life sciences data is imperative, as is rich background and experience in epigenetics research. Focus areas include computational elucidation of the epigenetic reprogramming of cellular state, inference of epigenetic control mechanisms involved in cancer onset, progression and relapse from therapy, and predictive patient stratification via epigenomic profiling. Responsibilities Working in collaboration with computational, biological and clinical scientists across the Celgene Research and Early Development organization, responsibilities include but are not limited to: • Pursuit and supervision of leading computational biology research towards key Celgene scientific objectives, including line management of junior staff. • Active participation as a core team member in the Epigenetics Thematic Center of Excellence (TCoE). • Coordinated application of novel computational analysis and biological interpretation approaches to leverage internal, public and partner datasets and empower data-driven decisions across therapeutic programs. • Multi-disciplinary collaboration to investigate compound and disease properties and influence decisions from target prioritization through to translational development. • Data integration across assay platforms and knowledge transfer from pre-clinical experiments to clinical trials. • Participation in and oversight of scientific report writing. Presentation of methods, results and conclusions to a publishable standard. • Contribution to planning and execution of collaborative projects with leading academic and commercial research groups worldwide. *LI-JW1 J2W:PR Qualifications PhD and Post-doctoral experience in relevant discipline Background experience & complementary knowledge • A Ph.D. in computational biology, bioinformatics, computer science, or related field from a recognized higher-education establishment. • 7+ years post-doctoral experience of inter-disciplinary computational and epigenetics research, in academic or pharma/biotechnology scenarios. • Previous experience of research supervision and track record of peer-reviewed publication in relevant scientific journals. • Expertise in algorithmic implementation, statistical programming and data manipulation, using e.g. R/Bioconductor, Matlab, Python, and contemporary, open-source bioinformatics tools and database structures. • Proven problem-solving skills, collaborative nature and adaptability across disciplines; An inter-disciplinary background involving Oncology and/or Translational Research in a university, hospital or biotechnology research environment would be desirable. • Excellent verbal and written communication skills. Fluent verbal and written English language skills prerequisite. Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S. Req ID: 15002157 Primary Location: United States-California-San Francisco Job: Research and Development Organization: Signal Schedule: Regular Shift: Standard Employee Status: Individual Contributor Job Type: Full-time Job Level: Day Job Travel: No Job Posting: 2015-12-16 00:00:00.0
Additional Info:
[Click Here to Access the Original Job Post]
Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture. Overview We seek a talented, collaborative inter-disciplinary scientist to lead work on the computational analysis of high-dimensional tissue, cell and molecular profiling data. This individual will play a key scientific role leveraging innovative computational analysis strategies and rich patient data to empower data-driven decisions for therapeutic programs in Celgene’s Epigenetics Thematic Center of Excellence (TCoE). The role will align directly with the Celgene mission to improve therapeutic outcomes in complex diseases of unmet medical need. Applications range from providing deep insight into therapeutic mechanisms of action for both existing and novel therapies, to the identification of novel targets and prediction of patient phenotypes associated with response to therapy. Analysis scenarios involve data from epigenomic, transcriptomic, proteomic, genomic, and wider cell-molecular profiling platforms. Expertise in the analysis and interpretation of next-generation sequencing data is prerequisite. The position would suit an individual with strong scientific leadership potential and excellent communication and collaboration skills. Applications are encouraged from those looking to bridge the gap between academic and industrial research environments to impact delivery of truly innovative and life-changing therapies. Strong interest in the inter-disciplinary application of computational analysis methods to life sciences data is imperative, as is rich background and experience in epigenetics research. Focus areas include computational elucidation of the epigenetic reprogramming of cellular state, inference of epigenetic control mechanisms involved in cancer onset, progression and relapse from therapy, and predictive patient stratification via epigenomic profiling. Responsibilities Working in collaboration with computational, biological and clinical scientists across the Celgene Research and Early Development organization, responsibilities include but are not limited to: • Pursuit and supervision of leading computational biology research towards key Celgene scientific objectives, including line management of junior staff. • Active participation as a core team member in the Epigenetics Thematic Center of Excellence (TCoE). • Coordinated application of novel computational analysis and biological interpretation approaches to leverage internal, public and partner datasets and empower data-driven decisions across therapeutic programs. • Multi-disciplinary collaboration to investigate compound and disease properties and influence decisions from target prioritization through to translational development. • Data integration across assay platforms and knowledge transfer from pre-clinical experiments to clinical trials. • Participation in and oversight of scientific report writing. Presentation of methods, results and conclusions to a publishable standard. • Contribution to planning and execution of collaborative projects with leading academic and commercial research groups worldwide. *LI-JW1 J2W:PR Qualifications PhD and Post-doctoral experience in relevant discipline Background experience & complementary knowledge • A Ph.D. in computational biology, bioinformatics, computer science, or related field from a recognized higher-education establishment. • 7+ years post-doctoral experience of inter-disciplinary computational and epigenetics research, in academic or pharma/biotechnology scenarios. • Previous experience of research supervision and track record of peer-reviewed publication in relevant scientific journals. • Expertise in algorithmic implementation, statistical programming and data manipulation, using e.g. R/Bioconductor, Matlab, Python, and contemporary, open-source bioinformatics tools and database structures. • Proven problem-solving skills, collaborative nature and adaptability across disciplines; An inter-disciplinary background involving Oncology and/or Translational Research in a university, hospital or biotechnology research environment would be desirable. • Excellent verbal and written communication skills. Fluent verbal and written English language skills prerequisite. Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S. Req ID: 15002157 Primary Location: United States-California-San Francisco Job: Research and Development Organization: Signal Schedule: Regular Shift: Standard Employee Status: Individual Contributor Job Type: Full-time Job Level: Day Job Travel: No Job Posting: 2015-12-16 00:00:00.0
Requeriments :
Skills :
- Bioinformatics
- Computational Biology
- Programing in Python
- Programing Skills
- Programming in Matlab
- Programming in R
Areas :
Additional Info:
[Click Here to Access the Original Job Post]