Job Description:
We are seeking a Principal Scientist to lead projects in Systems and Computational Immunology in the Precision Immunology Cluster of our Immunology & Inflammation Research Therapeutic Area. The candidate will use systems/computational immunology and statistical approaches to analyze immune and genomics profiling data for the identification of new drug targets and molecular biomarkers to be used in precision medicine. He/She will work closely with other disciplines across Sanofi to drive early discovery research programs into early clinical development, providing scientific and technical leadership. Summary of Key Responsibilities:
Additional Info:
The Immunology and Inflammation Research and Early Development Therapeutic Area in Sanofi is building a world-class immunology team and is seeking highly motivated computational scientists and data analysts to develop and apply systems biology methods to the study of novel therapies in the fields of Type 2 Immunity and Fibrosis, Immune Checkpoint Biology, Type 1 Diabetes, Targeted Autoimmunity and Innate Immunity. Sanofi US Services, Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. Sanofi is a global healthcare leader focused on patients' needs, engaged in the research, development, manufacturing and marketing of therapeutic solutions focused on patients’ needs. Sanofi has core strengths in diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets and Sanofi Genzyme. At Sanofi, our ambition is to be an integrated global healthcare company, focused on patients’ needs. Much more than just a leading pharmaceutical company, Sanofi is committed to transforming scientific innovations into solutions and services that protect health, enhance life, and respond to the needs of the 7 billion people in the world. We trust our ambition to guide and inspire us as we work to create a future with optimal health and wellness for everyone.[Click Here to Access the Original Job Post]
We are seeking a Principal Scientist to lead projects in Systems and Computational Immunology in the Precision Immunology Cluster of our Immunology & Inflammation Research Therapeutic Area. The candidate will use systems/computational immunology and statistical approaches to analyze immune and genomics profiling data for the identification of new drug targets and molecular biomarkers to be used in precision medicine. He/She will work closely with other disciplines across Sanofi to drive early discovery research programs into early clinical development, providing scientific and technical leadership. Summary of Key Responsibilities:
- Lead systems and computational immunology studies for identifying novel targets, biomarkers and pathways to stratify and treat chronic inflammatory and autoimmune diseases; connecting cutting-edge science with unmet medical need.
- Lead development of computational and statistical methodologies for the integrative analysis of clinical, molecular and immune data sets.
- Lead experimental study designs and methodological developments to address immunological questions by running statistically powered data analysis studies
- Proactively engage with experiments immunologists, clinicians and cluster team members to foster inter-disciplinary exchanges and translate data analysis results into immunological developments and actionable experimental or clinical research plans.
- Coordinate research efforts and make key technical contributions affecting the direction of the group and/or project.
- Build efficient interactions with collaborators within and outside the Immunology and Inflammation Research and Early Development Therapeutic Area.
- Provide scientific expertise, establish and manage external scientific collaborations, monitor external market, and provide critical assessment.
- Provide scientific leadership to scientists and research associates, train the team, and promote their career development.
- Provide and promote support for operational excellence according to Sanofi values and ethics.
- Prepare publications, research and clinical/regulatory documentation in accordance with Sanofi quality standards.
- Ph.D. in a computational biology, biostatistics, mathematics or related fields with a minimum of 6 years of industry or academic experience
- Deep expertise in data analysis, systems and computational biology applied to translational and immunology research, and excellent record of research and recent publications in the field.
- Deep knowledge of biostatistics and machine learning methods
- Strong interest and understanding of immunology
- Excellent programming skills (at least one among R and Matlab and at least one among C/C++, Java, Perl/Python)
- Experience with cross-functional projects involving the use of genomics and immune profiling data to generate novel hypotheses, understand mechanisms of actions, identifying candidate targets and biomarkers
- Deep knowledge of biological, genomics and immune data resources
- Good knowledge of relational databases and SQL
- Strong people organizational and presentation skills
- Excellent written and oral communication skills
- Excellent interpersonal and team skills; track record of success working collaboratively across disciplines in a matrix environment
Requeriments :
Skills :
- Biology
- Biostatistics
- Computational Biology
- genomic
- immunology
- Machine Learning
- Programing in C
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in Java
- Programming in Matlab
- Programming in PERL
- Programming in R
- SQL
- Statistics
- Systems Biology
Areas :
Additional Info:
The Immunology and Inflammation Research and Early Development Therapeutic Area in Sanofi is building a world-class immunology team and is seeking highly motivated computational scientists and data analysts to develop and apply systems biology methods to the study of novel therapies in the fields of Type 2 Immunity and Fibrosis, Immune Checkpoint Biology, Type 1 Diabetes, Targeted Autoimmunity and Innate Immunity. Sanofi US Services, Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. Sanofi is a global healthcare leader focused on patients' needs, engaged in the research, development, manufacturing and marketing of therapeutic solutions focused on patients’ needs. Sanofi has core strengths in diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets and Sanofi Genzyme. At Sanofi, our ambition is to be an integrated global healthcare company, focused on patients’ needs. Much more than just a leading pharmaceutical company, Sanofi is committed to transforming scientific innovations into solutions and services that protect health, enhance life, and respond to the needs of the 7 billion people in the world. We trust our ambition to guide and inspire us as we work to create a future with optimal health and wellness for everyone.[Click Here to Access the Original Job Post]