Job Description:
We are seeking open minded, cutting-edge individuals that love to push the boundaries of discovery Responsibilities:
Additional Info:
We provide the world's only system with the demonstrated ability to enable analysis and management of massively-large datasets composed of hundreds of thousands of human genomes. Unlike relational databases, which cannot efficiently handle the trillions of data points associated with even several dozen patient genomes, our platform has been used to successfully manage data from more than 350,000 whole genomes representing more than 40 million identified variants. Our informatics systems have been finely tuned on this massive knowledge base to provide users with unmatched confidence in their results. We are a growing global genome informatics and diagnostics company offering the world’s most proven technology for next generation sequence-based genetic testing and analysis, and seek to hire bioinformaticians with expertise in cancer genetics including both germline and tumor genetics. Principle Bioinformatics Scientist This is a full-time position based in our Cambridge, MA. We also have openings in our Shanghai Office By unlocking the unique talents of a varied pool of individuals, we foster the kind of collaboration and innovation that yield truly great work.
We are seeking open minded, cutting-edge individuals that love to push the boundaries of discovery Responsibilities:
- Working with our team of scientists and informatics staff on continued development and implementation of the tumor vs germline analysis based on our informatics pipeline applied to whole exome and whole genome datasets.
- Successful candidates will collaborate with our genetics and informatics groups to analyze our informatics systems for accuracy and content, and to further improve the analysis and interpretation of tumor-specific mutations.
- The successful candidate will be located at our Cambridge site and will work with both our genetics group and our informatics group.
- Additional duties include training of outside users and the testing and validation of new versions of the sequence analysis tools.
- PhD and a thorough understanding and experience in working with algorithms and software applications for high-throughput sequence data (NGS)
- 6-10 years' experience post PhD in Bioinformatics or Computational Biology.
- Expertise designing projects and experiments to solve biomedical questions.
- Strong experience of managing collaborative projects with multiple partners.
- Good international network in the computational biology community would be a huge advantage.
- Successful candidates will collaborate with our genetics and informatics groups to analyze our informatics systems for accuracy and content, and to further improve the analysis and interpretation of tumor-specific mutations.
- Significant programming experience is required (Unix shell programming and Python/Perl/Java/C++)
- Familiarity with some of the mainstream software packages for secondary analysis, such as BWA, GATK, MuTect, VarScan2, etc.
- Good overview of the key public reference databases for clinical variation data
- Additional experience in tumor biology and genetics would be an advantage.
Requeriments :
Skills :
- Genetics
- Lunix/Unix
- Next Generation Sequencing
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in Java
- Programming in PERL
- Shell scripting
Areas :
Additional Info:
We provide the world's only system with the demonstrated ability to enable analysis and management of massively-large datasets composed of hundreds of thousands of human genomes. Unlike relational databases, which cannot efficiently handle the trillions of data points associated with even several dozen patient genomes, our platform has been used to successfully manage data from more than 350,000 whole genomes representing more than 40 million identified variants. Our informatics systems have been finely tuned on this massive knowledge base to provide users with unmatched confidence in their results. We are a growing global genome informatics and diagnostics company offering the world’s most proven technology for next generation sequence-based genetic testing and analysis, and seek to hire bioinformaticians with expertise in cancer genetics including both germline and tumor genetics. Principle Bioinformatics Scientist This is a full-time position based in our Cambridge, MA. We also have openings in our Shanghai Office By unlocking the unique talents of a varied pool of individuals, we foster the kind of collaboration and innovation that yield truly great work.
- We have clear, professional and respectful communication with everyone
- We are all responsible for cutting-edge innovation
- We are a TEAM
- We balance critical thinking with executionWe care about employee’s professional and personal fulfillment
- We are a entrepreneurial EEO employer committed to a diverse and dynamic workplace.