Job ID: 374899
Job date: 2017-10-03
End Date:
Company : Twist Bioscience Country : Role : Research Scientist
Job date: 2017-10-03
End Date:
Company : Twist Bioscience Country : Role : Research Scientist
Job Description:
The R&D Bioinformatics Scientist, NGS will be an early addition to the bioinformatics capability within Twist R&D and will play a key role in expanding Twist’s Next-Generation Sequencing product portfolio. The R&D team designs and develops Next-Generation Sequencing based methods and applications, and works with other departments within Twist to cover all aspects of products from concept to development to commercial launch. The successful candidate will be responsible for: Collaborating with scientist and research associates in all phases of R&D work including experimental design, data analysis, data interpretation, and next iterations. Performing design and analysis for development of NGS products and applications read alignment, targeted sequencing, mapping, annotation, and variant calling. Writing and packaging off-the-shelf scripts into custom pipelines for NGS data analysis, enabling data analysis by non-bioinformaticians.
Additional Info:
About Twist Bioscience: At Twist Bioscience, our expertise is accelerating science and innovation by leveraging the power of scale. We have developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a high throughput silicon platform capable of producing synthetic biology tools, including genes, oligonucleotide pools and variant libraries. Our platform overcomes the current inefficiencies of synthetic DNA production, and enables cost-effective, rapid, high-quality and high throughput synthetic gene production, which in turn, expedites the design, build, test cycle to enable personalized medicines, pharmaceuticals, sustainable chemical production, improved agriculture production, diagnostics, biodetection and data storage. For more information, please visit www.twistbioscience.com. Twist Bioscience is on Twitter. Sign up to follow our Twitter feed @TwistBioscience at https://twitter.com/TwistBioscience. Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.[Click Here to Access the Original Job Post]
The R&D Bioinformatics Scientist, NGS will be an early addition to the bioinformatics capability within Twist R&D and will play a key role in expanding Twist’s Next-Generation Sequencing product portfolio. The R&D team designs and develops Next-Generation Sequencing based methods and applications, and works with other departments within Twist to cover all aspects of products from concept to development to commercial launch. The successful candidate will be responsible for: Collaborating with scientist and research associates in all phases of R&D work including experimental design, data analysis, data interpretation, and next iterations. Performing design and analysis for development of NGS products and applications read alignment, targeted sequencing, mapping, annotation, and variant calling. Writing and packaging off-the-shelf scripts into custom pipelines for NGS data analysis, enabling data analysis by non-bioinformaticians.
Requirements
Requirements:- M.S. or Ph.D. degree in Genetics, Biology, Bioinformatics, Biostatistics, Computational Biology, Computer Science, or related field
- Prior experience at a NGS company or research lab
- Deep understanding of next generation sequencing methods, platform-specific bias and errors, and data interpretation
- Hands-on experience with large-scale genomic data (e.g. whole genome sequencing, exome-seq, target enrichment, amplicon sequencing, RNA-seq, etc.)
- Hands-on experience with genome alignment, mapping, variant calling and annotation tools
- Familiarity with human and mammalian genomics, standard genomic databases (UCSC, EnsEMBL, NCBI), formats, and tools.
- Proficiency in python, ruby, perl, or another high-level scripting language (Python highly preferred)
- Familiarity with UNIX-based operating systems and shell scripting
- Excellent data analysis and visualization skills (Tableau, R, matplotlib, or similar)
- Excellent understanding of molecular biology and cell biology
- Familiarity with genetic testing, cancer and rare disease genomics.
- Familiarity with source control (git, subversion)
- Experience with LIMS and data acquisition from lab instruments
- Experience with UI development for non-programing users
- Knowledge of at least one compiled language such as C/C++, Java, or C#
Requeriments :
- M.Sc. or higher Degree in Bioinformatics
- M.Sc. or higher Degree in computational biology
- M.Sc. or higher Degree in Computer Science
- Master’s Degree in Genetics
Skills :
- Cell Biology
- Genetics
- genomic
- LIMS
- Lunix/Unix
- molecular biology
- Next Generation Sequencing
- Programing in C
- Programing in C++
- Programing in Python
- Programming in C#
- Programming in Java
- Programming in PERL
- Programming in R
- RNA-seq
- Shell scripting
Areas :
Additional Info:
About Twist Bioscience: At Twist Bioscience, our expertise is accelerating science and innovation by leveraging the power of scale. We have developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a high throughput silicon platform capable of producing synthetic biology tools, including genes, oligonucleotide pools and variant libraries. Our platform overcomes the current inefficiencies of synthetic DNA production, and enables cost-effective, rapid, high-quality and high throughput synthetic gene production, which in turn, expedites the design, build, test cycle to enable personalized medicines, pharmaceuticals, sustainable chemical production, improved agriculture production, diagnostics, biodetection and data storage. For more information, please visit www.twistbioscience.com. Twist Bioscience is on Twitter. Sign up to follow our Twitter feed @TwistBioscience at https://twitter.com/TwistBioscience. Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.[Click Here to Access the Original Job Post]