Job ID: H94704
Job date: 2018-01-30
End Date:
Company : UCLA Health Country : Role : Research Scientist
Job date: 2018-01-30
End Date:
Company : UCLA Health Country : Role : Research Scientist
Job Description:
Under supervision of the Principal Investigator, the SRA-I provides technical and operational support for the design, implementation, and maintenance of existing and new pipelines for genetic data analysis. Job duties include: preprocessing next-generation sequencing (NGS) data (data conversion, sequence alignments, quality control); statistical analysis of NGS data using current analysis pipelines (variant calling, association analysis, enrichment analysis); improving current pipelines and developing new pipelines for NGS data with the latest statistical approaches; preparing analysis reports; maintaining NGS data and results for future projects; providing assistance to lab members for NGS data analysis.
Additional Info:
[Click Here to Access the Original Job Post]
Under supervision of the Principal Investigator, the SRA-I provides technical and operational support for the design, implementation, and maintenance of existing and new pipelines for genetic data analysis. Job duties include: preprocessing next-generation sequencing (NGS) data (data conversion, sequence alignments, quality control); statistical analysis of NGS data using current analysis pipelines (variant calling, association analysis, enrichment analysis); improving current pipelines and developing new pipelines for NGS data with the latest statistical approaches; preparing analysis reports; maintaining NGS data and results for future projects; providing assistance to lab members for NGS data analysis.
- Download, convert, maintain, and preprocess next-generation sequencing (NGS) data from different sequencing projects such that they are appropriate for initial analysis.
- Perform sequence alignment and basic quality control using existing software packages on NGS data.
- Maintain and improve current analysis pipelines for variant calling, quality control, association, enrichment, gene set analyses of NGS data in a large UCLA cluster environment.
- Develop new pipelines for analyzing NGS data with the latest statistical approaches and integrate them with the current pipelines in a large UCLA cluster environment.
- Perform statistical analysis on large-scale whole-genome sequencing data of neuropsychiatric and neurodegenerative disorders by utilizing the existing and new analysis pipelines for NGS data.
- Prepare materials (tables, figures, analytic summary, interpretations) for research reports, presentations and manuscripts
- Assist lab members in analyzing NGS data for accuracy and appropriateness.
- This is a limited position, may convert to career.
- Preferred: BS degree in Biostatistics/Bioinformatics/Biochemistry or related field.
- Experience with programming or scripting languages (C/C++/Java/Python).
- Experience with linux environment and Sun Grid Engine.
- Experience with applying existing software packages to data.
- General knowledge of basic statistics including linear/logistic regression, t-test, and PCA.
- Knowledge of computational/statistical genetics.
- Experience with next-generation sequencing data analysis.
- Ability to multi-task.
- Ability to work independently and to take directions.
- Excellent attention to details.
- Ability to work in a collaborative environment.
- Ability to read and understand research papers on neurobehavioral issues and statistical methodology.
- General knowledge of University procedures.
- Willingness to work occasional overtime in order to meet deadlines related to grant applications and publications.
Requeriments :
Skills :
- Genetics
- Lunix/Unix
- Next Generation Sequencing
- Programing in C
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in Java
- Statistics
Areas :
Additional Info:
[Click Here to Access the Original Job Post]