Research Bioinformatician I

Job ID: 400445519
Job date: 2017-09-03
End Date:

Company : Cedars-Sinai 

Country :

Role : Research Scientist 


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Job Description:
Cedars Sinai’s Biomedical Sciences is looking for a Research Bioinformatician to join the Genomics Core.

Under close supervision, the Research Bioinformatician I perform general bioinformatics analysis and software support for genomics projects. The RBI will manage genomic data including loading and querying data from database system and public repositories and transform and merge multi-level genomic data into user friendly formats, assists in development, test, and maintenance of modular software pipelines, provide daily bioinformatics data analysis, preliminary interpretation of the data, and reports of the results for possible publications.

Specifically, this position will be working in the Genomics core as a part of an integrated team of wet lab and informatic scientists. The main responsibility will be to manipulate large datasets from whole genome type scans, perform tests to determine biological significance, and visualize biologically meaningful data. This is a very dynamic position for instance, where variety of basic analysis tools to determine things will be used, like genetic linkage, gene expression profiles, and molecular classifiers from data generated from microarrays, qPCR data, and Next Gen Sequencing. The position is expected to assist in specific advanced collaborations with the Core Directors collaborative lead research as well as help to translate developmental pipelines for filtering and analyzing these large datasets. The position summarizes data analyses results in the form suitable as the basis for the first draft of written reports, and makes preliminary interpretations of the data. Manages data including loading and querying data from database systems, downloading genomic data from public repositories, and transforming data to the necessary formats. Helps to identify, evaluate, and incorporate relevant algorithms and software pipelines by reviewing pertinent literature in bioinformatics and computational biology.

Essential Job Duties And Skills :

  • Must have the ability to completely define an analytical approach for defined scientific questions.
  • The ability to interact with outside customers and/or functional peer groups.
  • Must have outstanding oral and written communication skills.
  • Ability to manage multiple assignments.
  • Strong ability to act in a consultative manner with investigators on data analysis; and be able to work independently, manage priorities, and accurately produce results in a timely manner.
  • Leads in the development of analytical pipelines for biological data. Leads in the development of innovative data analysis capabilities.
  • Strong ability to act in a consultative manner with investigators on data analysis; and be able to work independently, manage priorities, and accurately produce results in a timely manner.
  • Publishes collaborative research and gives presentations at meetings of biological, bioinformatic, or other professional groups, thereby reporting results of bioinformatic/biomedical research.
  • Prepares bioinformatics reports, manuscripts, and bioinformatics sections of grant applications.
  • Coordinates bio-analysis with scientists, bioinformatists, computer administrators, and wet lab staff.
  • Devises or develops new biological methods and techniques. Assists in validation of methods. Completes other duties as assigned.
Business Entity: CSMC - Cedars-Sinai Medical Center

Educational Requirements:

  • Master’s degree in Biostatistics, Statistics, Bioinformatics, Genetics or related field of molecular biology. PhD preferred.
  • Must have proven expertise in biostatistics, large-scale computing, biological data and bioinformatics.
Experience:
  • 0-3 years’ experience directly related to bioinformatics in genomics (i.e. genomics, transcriptomics, epigenomic, resequencing analysis, etc.). Must have experience in managing the development and deployment of systems that will be used for full integrated genomic analysis.
  • Must have expertise in correlating molecular and clinical measures, and in applying algorithms for clustering and classifying samples by molecular measures.
  • Must have R, Bioconductor, Perl, Python, Unix/Linux, SGE Programming knowledge.
Physical Demands: (e.g., lifting, standing, walking)
  • Ability to sit for moderate periods of time.
  • Ability to use a computer workstation for moderate periods of time.
  • Ability to walk and be on one’s feet for moderate periods of time.


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Additional Info:
Cedars-Sinai is a non-profit, academic, community-centric, Level 1 Trauma Center in Los Angeles, California. Recognized internationally, Cedars-Sinai brings together top healthcare professionals collaborating to provide exceptional patient care.

A combination of patient satisfaction scores, clinical performance initiatives, excellent medical outcomes, national designations and awards and ongoing research and academic programs have earned Cedars-Sinai a top spot on the Honor Roll in the 2014-15 issue of America's Best Hospitals by U.S. News & World Report.

Out of nearly 5,000 hospitals surveyed for the annual rankings, Cedars-Sinai is among just 17 hospitals nationwide to earn the magazine’s Honor Roll designation. To be named to the Honor Roll, a hospital must be rated among the nation’s top 50 programs in at least six specialties. Cedars-Sinai was ranked in 12 categories, including: Cancer; Cardiology and Heart Surgery; Diabetes and Endocrinology; Ear, Nose and Throat; Gastroenterology & GI Surgery; Geriatrics; Gynecology; Nephrology, Neurology and Neurosurgery; Orthopedics; Pulmonology; and Urology.

Cedars-Sinai has also received its fourth consecutive Magnet® recognition for nursing excellence from the American Nurses Credentialing Center (ANCC), becoming the hospital with the longest-running Magnet designation in California.

Nationwide, only about 5% of hospitals have earned the four-year Magnet designation. Cedars-Sinai was the first Southern California hospital to earn the Magnet honor in 2000, and one of only six hospitals to receive this designation three times. Studies show that Magnet hospitals tend to have lower mortality and infection rates, as well as higher patient satisfaction and nurse staffing levels.

The quality and dedication of our talented nurses, allied health professionals and physicians make Cedars-Sinai one of the nation's leading academic medical centers.

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