Job ID: 3020090
Job date: 2017-02-15
End Date:
Company : Massachusetts General Hospital Country : Role : Research Scientist
Job date: 2017-02-15
End Date:
Company : Massachusetts General Hospital Country : Role : Research Scientist
Job Description:
The Ragon Institute of MGH, MIT and Harvard located in Kendall Square in Cambridge, MA has an opening in the Allen laboratory (http://www.ragoninstitute.org/portfolio-item/allen-lab/) for a highly motivated postdoctoral fellow to study the role of HIV sequence evolution in the development of broadly neutralizing antibodies. This position requires a Ph.D. or an M.D. with a background in humoral immunity, evolutionary biology, and/or Bioinformatics. Research will focus on elucidating the role that viral evolution and escape from humoral immune responses plays in the development and maturation of broadly neutralizing antibodies to HIV. Efforts will include application of next generation sequencing (NGS) technologies to address these questions and development of advanced comparative genomic tools for the analysis of large viral genomic NGS datasets. Goals are to understand the role of HIV sequence evolution in the development of broadly neutralizing antibodies and apply this knowledge to design the effective components of an HIV vaccine. State-of-the-art facilities are available within an exceptionally energetic research setting. Job Duties: Under the direction of the principal investigator the applicant independently carries out daily activities of the laboratory. -Performs molecular biology and cell-based assays utilizing standard techniques (DNA/RNA extraction and analysis, standard and quantitative PCR, site-directed mutagenesis, neutralization assays, ELISAs). -Next-generation Illumina library construction and sequencing. -Bioinformatic analysis of conventional bulk and next-generation sequence data. -Develop advanced comparative genomic tools for the analysis of large viral genomic NGS datasets. -Detailed documentation of the experimental work. Qualifications: -A Ph.D. or M.D. with relevant experience in humoral immunity, evolutionary biology, and/or bioinformatics. -Strong candidates will have demonstrated experience in the immunology or virology of infectious diseases and/or experience with NGS analysis and phylogenetic tools. -Candidates must be highly motivated and independent, with the ability to work in a dynamic team environment. -Good organizational skills and excellent attention to detail. -Ability to perform as a team member and must have good interpersonal skills.
Additional Info:
EEO Statement: Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.[Click Here to Access the Original Job Post]
The Ragon Institute of MGH, MIT and Harvard located in Kendall Square in Cambridge, MA has an opening in the Allen laboratory (http://www.ragoninstitute.org/portfolio-item/allen-lab/) for a highly motivated postdoctoral fellow to study the role of HIV sequence evolution in the development of broadly neutralizing antibodies. This position requires a Ph.D. or an M.D. with a background in humoral immunity, evolutionary biology, and/or Bioinformatics. Research will focus on elucidating the role that viral evolution and escape from humoral immune responses plays in the development and maturation of broadly neutralizing antibodies to HIV. Efforts will include application of next generation sequencing (NGS) technologies to address these questions and development of advanced comparative genomic tools for the analysis of large viral genomic NGS datasets. Goals are to understand the role of HIV sequence evolution in the development of broadly neutralizing antibodies and apply this knowledge to design the effective components of an HIV vaccine. State-of-the-art facilities are available within an exceptionally energetic research setting. Job Duties: Under the direction of the principal investigator the applicant independently carries out daily activities of the laboratory. -Performs molecular biology and cell-based assays utilizing standard techniques (DNA/RNA extraction and analysis, standard and quantitative PCR, site-directed mutagenesis, neutralization assays, ELISAs). -Next-generation Illumina library construction and sequencing. -Bioinformatic analysis of conventional bulk and next-generation sequence data. -Develop advanced comparative genomic tools for the analysis of large viral genomic NGS datasets. -Detailed documentation of the experimental work. Qualifications: -A Ph.D. or M.D. with relevant experience in humoral immunity, evolutionary biology, and/or bioinformatics. -Strong candidates will have demonstrated experience in the immunology or virology of infectious diseases and/or experience with NGS analysis and phylogenetic tools. -Candidates must be highly motivated and independent, with the ability to work in a dynamic team environment. -Good organizational skills and excellent attention to detail. -Ability to perform as a team member and must have good interpersonal skills.
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Additional Info:
EEO Statement: Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.[Click Here to Access the Original Job Post]