Job ID:
Job date: 2018-04-24
End Date: 2018-06-23
Company : Genome Sciences Centre Country : Canada Role : Programmer | Research Scientist
Job date: 2018-04-24
End Date: 2018-06-23
Company : Genome Sciences Centre Country : Canada Role : Programmer | Research Scientist
Job Description:
The successful applicant will work closely with the Clinical Genomics group which is responsible for developing high-throughput, clinically accredited pipelines to aid in identifying pathogenic alterations in cancer. This project involves the development of a new assay for Lymphoma patients with the goal of individualized patient management.
Additional Info:
[Click Here to Access the Original Job Post]
The successful applicant will work closely with the Clinical Genomics group which is responsible for developing high-throughput, clinically accredited pipelines to aid in identifying pathogenic alterations in cancer. This project involves the development of a new assay for Lymphoma patients with the goal of individualized patient management.
Responsibilities:
Duties/Accountabilities: • Modification and development of bioinformatic pipelines to analyse lymphoma RNA-Seq and other genomic data yielding clinical grade variant and expression data • Assist in choosing and modifying targets for assay development •Analysis of NGS data to investigate clonality, hypermutation, and intergenic translocations • Development and assessment of bioinformatic tools for RNA-Seq expression analysis and variant calling • Development and assessment of bioinformatic tools for determining the clinical significance of detected variants • Statistical analysis to determine analytical sensitivity and specificity of obtained results • Development of software pipelines for analyzing next-generation sequencing data • Support of research staff by providing analysis and software tools • Contributions to the writing of research publications Skills and Abilities: • Knowledge of RNA-Seq and other genomic data analysis, including expression analysis, structural variant detection, and variant-calling. • Experience working in a Unix environment, including experience with shell scripting and common command-line tools • Expertise in one or more scripting language(s) (e.g. Python) • Experience working with next-generation sequencing data and tools (i.e. tools for alignment and variant-calling) • Expertise in statistical analysis using modern computational tools. Experience with any relevant tools will be considered, but R and Python are preferred • Experience writing reports of results in accurate and concise language; expertise in scientific/technical writing is required • Experience with methods in high-dimensional data analysis for bioinformatics such as clustering, machine learning and data mining would be assets • Experience with software testing and cluster computing would be assets • Familiarity with cancer genetics would be an asset, as would a history of publications in relevant fields. The successful candidate will also have: • Excellent verbal and written communication skills • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment. • Demonstrated ability to efficiently organize work assignments and establish priorities. Qualifications: • Graduation from a recognized Bachelor of Science Program in Bioinformatics, Biological Sciences, Statistics, Engineering, or Computer Science. A Master’s or Doctoral degree in a relevant field would be a strong asset. • Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the Medical Director of the Centre for Clinical Genomics. Location: Vancouver, BC, Canada Job Type: Staff Degree Level Required: Bachelor'sRequeriments :
Skills :
- Bioinformatics
- Data Mining
- genomic
- Lunix/Unix
- Machine Learning
- Next Generation Sequencing
- Programing in Python
- Programming in R
- RNA-seq
- Shell scripting
- Statistics
Areas :
Additional Info:
[Click Here to Access the Original Job Post]