Job Description:
We are seeking a highly motivated bioinformatics scientist to take a key role in statistical analysis of genomics and next generation sequencing data to support multiple therapeutic areas (liver diseases, HIV cure, inflammation, immunotherapy, etc.) from target evaluation to biomarker discovery. The successful candidate will have the opportunity to work in a fast-paced and highly collaborative environment and will be responsible for developing and employing rigorous statistical modeling and bioinformatics methods, interpreting and integrating large scale datasets to enable research biology objectives. -Develop and implement, in collaboration with research and biomarker scientists, statistical analysis and quality control of microarray and next generation sequencing data (e.g. RNA-seq, exome-seq, CHIP-seq, whole genome sequencing, etc). -Apply and create statistical and computational tools for analysis of large genomic and pharmacogenomics data sets from publicly available, commercial, or proprietary genomic databases to enable target identification/assessment, understanding of MOA, disease subtypes, etc. -Design and apply bioinformatics algorithms, unsupervised and supervised methods, univariate and multivariate regression analyses, etc. to enable the discovery of predictive and prognostic biomarkers and biomarker signatures utilizing preclinical and clinical data . Essential Duties and Job Functions: -Designs and implements complex software programs that support goal of project teams. -Identifies and introduces new technology and/or methods to the organization and trains junior staff. -Investigates project feasibility and estimates project cost and resource needs. -Collaborates with research scientists to plan software requirements. -Manages tasks and personnel involved in software validation. -Approves changes to database systems and estimates impact of changes. -Ensures SOPs for business area are current and appropriate. -Manages data transfer agreements with contract labs supporting clinical trials. Provides technical solutions to a wide range of difficult problems. Solutions are innovative, thorough, practicable, and consistent with organization objectives. -Demonstrate the ability to organize, prioritize, and coordinate multiple projects and meet timelines. -Uses strong communication skills (both verbal and written) and interpersonal skills to communicate objectives and results. Knowledge, Experience and Skills: -A PhD in bioinformatics, computer science, computational biology, genomics, or a related field. -7+ years of experience with MS degree in a related scientific discipline. -3+ years of experience with computational annotation and analysis of large-scale multidisciplinary datasets including genomic data. -Proficient in object-oriented programming using JAVA, C++, or C#. -Proficient in GUI development and data visualization. -Proficient in relational databases and SQL. -Hands-on experience with Linux/Unix platforms and high-performance computing environment. -Experience with statistical analysis of biomedical data using SAS® or R software.
Additional Info:
As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.[Click Here to Access the Original Job Post]
We are seeking a highly motivated bioinformatics scientist to take a key role in statistical analysis of genomics and next generation sequencing data to support multiple therapeutic areas (liver diseases, HIV cure, inflammation, immunotherapy, etc.) from target evaluation to biomarker discovery. The successful candidate will have the opportunity to work in a fast-paced and highly collaborative environment and will be responsible for developing and employing rigorous statistical modeling and bioinformatics methods, interpreting and integrating large scale datasets to enable research biology objectives. -Develop and implement, in collaboration with research and biomarker scientists, statistical analysis and quality control of microarray and next generation sequencing data (e.g. RNA-seq, exome-seq, CHIP-seq, whole genome sequencing, etc). -Apply and create statistical and computational tools for analysis of large genomic and pharmacogenomics data sets from publicly available, commercial, or proprietary genomic databases to enable target identification/assessment, understanding of MOA, disease subtypes, etc. -Design and apply bioinformatics algorithms, unsupervised and supervised methods, univariate and multivariate regression analyses, etc. to enable the discovery of predictive and prognostic biomarkers and biomarker signatures utilizing preclinical and clinical data . Essential Duties and Job Functions: -Designs and implements complex software programs that support goal of project teams. -Identifies and introduces new technology and/or methods to the organization and trains junior staff. -Investigates project feasibility and estimates project cost and resource needs. -Collaborates with research scientists to plan software requirements. -Manages tasks and personnel involved in software validation. -Approves changes to database systems and estimates impact of changes. -Ensures SOPs for business area are current and appropriate. -Manages data transfer agreements with contract labs supporting clinical trials. Provides technical solutions to a wide range of difficult problems. Solutions are innovative, thorough, practicable, and consistent with organization objectives. -Demonstrate the ability to organize, prioritize, and coordinate multiple projects and meet timelines. -Uses strong communication skills (both verbal and written) and interpersonal skills to communicate objectives and results. Knowledge, Experience and Skills: -A PhD in bioinformatics, computer science, computational biology, genomics, or a related field. -7+ years of experience with MS degree in a related scientific discipline. -3+ years of experience with computational annotation and analysis of large-scale multidisciplinary datasets including genomic data. -Proficient in object-oriented programming using JAVA, C++, or C#. -Proficient in GUI development and data visualization. -Proficient in relational databases and SQL. -Hands-on experience with Linux/Unix platforms and high-performance computing environment. -Experience with statistical analysis of biomedical data using SAS® or R software.
Requeriments :
Skills :
- Biomarker Discovery
- genomic
- HPC
- Lunix/Unix
- Microarray
- Next Generation Sequencing
- Programing in C++
- Programming in C#
- Programming in Java
- Software Design
- SQL
- Statistics
Areas :
Additional Info:
As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.[Click Here to Access the Original Job Post]