Research Technician - High Throughput Crystallization EMBL - European Molecular Biology Laboratory Location: Grenoble Salary: Grade 4, 5 or 6, depending on experience and qualifications Hours: Full Time Contract Type: Contract / Temporary Placed on: 21st October 2015 Closes: 29th November 2015 Job Ref: GR_00082
Job Description
The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy).
A Research Technician position is available at the High Throughput Crystallization Laboratory (HTX-Lab) of the EMBL Grenoble Outstation.
The HTX Lab is actively involved in the development of new concepts and methods in macromolecular crystallization, including the recently developed CrystalDirect approach for automated crystal harvesting and offers access to crystallization screening services to both local and European researchers through the EC-funded BioStruct-X and iNEXT projects.
The successful candidate will contribute to the development of automated macromolecular crystallography pipelines integrating crystallization, automated crystal mounting and X-ray data collection in collaboration with the HTX lab members and other teams in the Outstation and the ESRF. These pipelines will be applied to the structural analysis of proteins of biomedical relevance. He/She will also contribute to the operation of robotic equipment associated to the crystallization screening services offered by the HTX lab.
Tasks will include development of integrated crystallography workflows, liaison with HTX lab users and operation of the crystallization platform comprising automated liquid handling, imaging and crystal harvesting systems. DNA cloning, protein expression and purification will be performed as part of the internal research projects. Additional tasks will include the management of orders and consumables for the HTX laboratory and general management and maintenance of robotic equipment (arranging with external companies for repairs when necessary).
Qualifications and Experience
Applicants should have a degree in biochemistry or a related field from a technical school or university, as well as excellent skills in protein handling and molecular biology. Experience in protein crystallization, macromolecular crystallography and the use of automated laboratory equipment will be highly valued. The ability to work within a team and communicate with users of the crystallization facility is essential. She/He should be willing to acquire further skills and contribute to the development of new methods. Fluency in English and good computer skills are mandatory. We are looking for a motivated and dynamic person with a desire to work in an international environment and to contribute to high quality research and services.
Application Instructions
Please apply online through www.embl.org/jobs
Additional Information
EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.
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