Scientific Programmer and Statistician : Hinxton, Cambridge, United Kingdom

Job ID: 573421
Job date: 2016-02-29
End Date:

Company : EMBL 

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Role : Research Scientist 


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Job Description:
Job Description Are you passionate about using computer science to understand biology? The Stegle research group at the European Bioinformatics Institute (EMBL-EBI) is looking for an experienced Scientific Programmer and Statistician to join their growing team. The Stegle group explores how genetic background and environment contribute to health and disease. EMBL-EBI, the UK site of the European Molecular Biology Laboratory (EMBL), has been a global leader in computational biology research since its inception in 1994. Located on the Wellcome Genome Campus, we are at the centre of one of the highest concentrations of technical and scientific expertise in the world. Our research spans fundamental methods in sequence analysis, multi-dimensional statistical analysis and data-driven biological discovery, from plant biology to mammalian development and disease. We are highly collaborative and interdisciplinary, regularly publishing high-impact works on sequence and structural alignment, genome analysis, basic biological breakthroughs, algorithms and methods of widespread importance. As a Scientific Programmer and Statistician, you would lead the development of scientific software developed by the Stegle group. One important area of work is the further development of LIMIX, a flexible software suite for genetic modelling. LIMIX has broad applications, and is used in quantitative genetics, cancer genomics and single-cell biology. It is central to achieving the aims of the EU-funded PanCanRisk project (http://www.pancanrisk.eu), and will be interlinked with other group activities, such as our projects in the Centre for Therapeutic Target Validation (https://www.targetvalidation.org) and the UK Human Pluripotent Stem Cell Initiative (http://www.hipsci.org). Your specific goals and tasks would be to:

  • Develop and implement advanced statistical genetics algorithms, in particular in the area of rare variant association tests and multiple phenotype association tests
  • Develop an efficient, flexible linear algebra backend within the LIMIX software suite
  • Implement cloud-enabling features in LIMIX and Docker environments to enable parallelised high-throughput analyses.
  Qualifications and Experience We are looking for a person who has the right skill set and is happy collaborating on a range of projects. Our new Scientific Programmer and Statistician should have:
  • Experience in developing scientific software
  • Research experience to MSc/PhD level or equivalent
  • Proficiency in R/Python or related statistical compute environments
  • Competence in software design
  • Programming skills in C++/Python/R or similar programing languages
  • Excellent communication skills - essential to effective collaboration within the team and our partners in other countries and institutions.
  Benefits EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. The remuneration package comprises a competitive salary, a comprehensive pension scheme and health insurance, educational and other family related benefits where applicable, as well as financial support for relocation and installation. We provide a dynamic, international working environment and have close ties with both the University of Cambridge and the Wellcome Trust Sanger Institute. EMBL-EBI staff also enjoy excellent sports facilities, a free shuttle bus to Cambridge and other nearby centres, an active sports and social club and an attractive working environment set in 55 acres of parkland. Application Instructions Please apply online through www.embl.org/jobs Additional Information We welcome applications irrespective of gender and appointment will be based on merit alone. Applications are welcome from all nationalities - visa information will be discussed in more depth with applicants selected for interview. Applications will close at 23.00 GMT on 27 March 2016. This position is limited to the contract duration.


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