Scientist, Biomarker

Job Description:
The Biomarker Scientist will work within the Translational Research team to support biomarker development and publication efforts by mining CTC morphology, protein chemistry and genomic data in context with patient diagnostic, therapeutic and disease outcomes to train and validate signatures to enable precision medicine.

ESSENTIAL FUNCTIONS:

• Drive publication writing for biomarker data including: abstracts, posters, white papers, & publications
• Manage multiple translational research biomarker project initiatives across multiple disease states
• Work closely with data scientist, biostatisticians to improve and augment biomarker data tactics and strategies
• Serve as lead in tumor biomarker discovery, cancer immunology projects to establish predictive biomarker hypotheses, including indication selection, sample accrual and biomarker selection strategy
• Provide strategic insight and guidance in biomarker strategies by contributing novel approaches and incorporating new technological capabilities
• Track predictive biomarker strategy progress through assay development, data analysis to data presentation, applying Precision Medicine resources and technologies as needed
• Establish alignment for predictive biomarker and patient selection strategies to ensure successful translation from preclinical project to clinical development
• Guide biomarker discovery research project to generate data that justify and/or inform the collection and analysis of clinical specimens
• Effectively support collaborative research projects with external KOLs
• Develop and assist in documentation of novel IP related to biomarker discoveries
• Perform data analysis as needed

ADDITIONAL DUTIES:

May perform additional duties as assigned or directed by management from time to time

EDUCATION/EXPERIENCE REQUIRED:

• Ph.D. in molecular, cellular biology, computational biology, bioinformatics, or related discipline.
• Domain knowledge in one or more solid tumor types; including understanding of patient management, disease progression, therapeutic standard of care required
• 3+ years working experience in tumor biomarker discovery and oncology diagnostic assay development
• Strong acumen in biomarker and clinical statistics
• Experience with data mining techniques (data preparation and warehousing, data storage and visualization)
• Demonstrated experience with data management and statistical packages (i.e. KNIME, R, etc.)

REQUIRED SKILLS:

• Strong scientific and technical writing skills
• Strong presentation skills
• Strong analytical and problem solving skills
• Strong statistical and bioinformatics acumen
• Strong collaboration and team skills
• Clear and transparent data strategy and communication
• Self-starter, capability to identify and resolve problems independently
• Experience working with pharma and/or KOLs

REQUIRED COMPETENCIES:

-Performance Orientation – Is driven by personal performance; achieves all objectives detailed in scorecards and comfortable with quantifiable assessments.

-Impact Orientation – Performs to stated objectives and driven to make an impact on company goals and patients’ lives.

-Competitive – Dedicated to a competitive spirit that supports the Epic Sciences’ goal to be the premier CTC technology in the industry.

-Sense of Urgency – Has the speed and agility dedicated to the company’s goals and performance. -Ability to Handle Pressure and Ambiguity – Comfortable with the pressure to be the best and the ability maintain composure and focus in situations of ambiguity and uncertainty.

-Confidence - Confident in one’s skills and abilities; pursues everything with energy; demonstrates the drive and a need to finish especially in the face of resistance or setbacks.

PHYSICAL DEMANDS:

• The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
• While performing the duties of this job, the employee is regularly required to talk or hear. The employee is frequently required to sit. The employee is occasionally required to stand; walk; use hands to finger, handle, or feel and reach with hands and arms.
• The employee must occasionally lift and/or move up to 10 pounds.
• Specific vision abilities required by this job include close vision, distance vision, color vision, peripheral vision, depth perception and ability to adjust focus.
• Standing for long periods of time.
• Transition from standing and sitting often.

WORK ENVIRONMENT:

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

-General office environment. Daily exposure to PCs and networks.

-May move heavy equipment and boxes.

-While performing the duties of this job, the employee is regularly exposed to fumes or airborne particles; toxic or caustic chemicals and risk of electrical shock. The employee is frequently exposed to risk of radiation and vibration. The employee is occasionally working near moving mechanical parts; extreme cold (non-weather) and extreme heat (non-weather).

-The noise level in the work environment is usually moderate.

Disclaimer:

The above statements are intended to describe the general nature and level of work performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of personnel so classified.

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Requeriments :

• Doctorate Degree

Skills :

• Bioinformatics
• Biomarker Discovery
• Data Mining
• Statistics

Areas :

• Bioinformatics

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Additional Info:
Epic Sciences, Inc. is developing novel diagnostics to personalize and advance the treatment and management of cancer. Epic’s mission is to enable the rapid and non-invasive detection of genetic and molecular changes in cancer throughout a patient’s journey. The company was founded on a powerful platform to identify and characterize rare cells, including circulating tumor cells (CTCs). Our technology helps match patients to targeted therapies and monitor for drug resistance, so that the best treatment path can be chosen at every clinical decision point. Today, we partner with leading pharmaceutical companies and major cancer centers around the world. Epic’s goal is to commercialize our technology to increase the success rate of cancer drugs in clinical trials and improve patient outcomes by providing physicians real-time information to guide treatment choices.

Epic Sciences is an Equal Opportunity Employer and committed to the principle of diversity

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