Job Description:
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish National Cancer Institute (NCI) research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers KEY ROLES/RESPONSIBILITIES The Scientist – Computational Chemist will:
Additional Info:
Leidos Overview: Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos will consider qualified applicants with criminal histories for employment in accordance with relevant Laws. Leidos is an Equal Opportunity Employer.[Click Here to Access the Original Job Post]
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish National Cancer Institute (NCI) research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers KEY ROLES/RESPONSIBILITIES The Scientist – Computational Chemist will:
- Work in support of the FNL/NCI RAS Initiative and work closely with a highly collaborative multidisciplinary team of chemists, biochemists, structural and cell biologists, to develop and optimize agents for use as RAS inhibitors
- Perform structure-based computer aided drug design and analysis for RAS as a target
- Provide computational support during hit validation studies
- Conduct hit-to-lead computational chemistry efforts around those targets/screens that yield advancable hits
Qualifications:
BASIC QUALIFICATIONS To be considered for this position, you must minimally meet the knowledge, skills and abilities listed below:- Possession of a PhD in a field related to computational chemistry, bioinformatics, pharmaceutical sciences, or in a related discipline from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) appropriate to biomedical research (Additional qualifying experience may be substituted for the required education).
- Foreign degrees must be evaluated for U.S. equivalency
- No work experience is required for appointment at this level
- Must be able to obtain and maintain a security clearance
- Expertise in X-ray crystallography
- Experience with biophysical techniques like isothermal calorimetry, surface plasmon resonance
- Experience in bioinformatics
- Strong publication record
- Expertise in structure based drug design (SBDD), quantitative structure-activity relationship studies (QSAR), pharmacophore based drug design, two-dimensional and three-dimensional structure based screening
- Must be highly collaborative, self-motivated and team oriented
- Must have excellent oral and written communication skills
- Ability to efficiently manage workload over multiple projects
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Additional Info:
Leidos Overview: Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos will consider qualified applicants with criminal histories for employment in accordance with relevant Laws. Leidos is an Equal Opportunity Employer.[Click Here to Access the Original Job Post]