Job ID:
Job date: 2018-04-19
End Date: 2018-06-18
Company : Brigham and Women’s Hospital Country : United States Role : Other
Job date: 2018-04-19
End Date: 2018-06-18
Company : Brigham and Women’s Hospital Country : United States Role : Other
Job Description:
The bioinformatician will play a central role in the management and analysis of single cell genomic data at the new Chromium 10X core facility at Brigham and Women’s Hospital. The core facility will run cutting edge experiments on single cell data, including but not limited to single cell RNA-seq, antibody oligo tagging for protein quantification, TCR and BCR sequencing for repertoire analysis, and multiplexed droplet experiments. The bioinformatician will have the opportunity to contribute scientifically to the implementation and testing novel algorithms, the development of specialized software and high throughput analysis pipelines, and the collaborative analysis of genomic and clinical data with senior scientists from Brigham and Women’s Hospital, Harvard Medical School, The Broad Institute, and the Dana Farber Cancer Institute. The bioinformatician will work closely with Dr. Soumya Raychaudhuri, senior scientists from the Harvard Medical School immunogenomics lab, as well as with outside collaborators. The bioinformatician will have access to computational resources from Partners Healthcare and the Broad Institute. Much of this role is flexible and can suit the talents and interests of capable scientists and engineers. PRINCIPAL DUTIES AND RESPONSIBILITIES: 1.Manage the storage, access, and dissemination of large amounts of data. 2.Develop robust computational pipelines for automated processing of single cell genomic data. 3.Implement and test novel algorithms from scientific literature. 4.Documentation of computational procedures and analyses for reproducible research. 5.Regularly communicate with lab members, collaborators, and technical staff from related core facilities. 6.In collaboration with senior scientific staff, initiate and foster scientific collaborations outside the lab. 7. All other duties as assigned. QUALIFICATIONS: Education:
Additional Info:
EEO Statement Brigham and Women’s Hospital is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, sexual orientation, protected veteran status, or on the basis of disability. Primary Location : MA-Boston-BWH Longwood Medical Area Work Locations : BWH Longwood Medical Area 75 Francis Street Boston 02115 Job : Business and Systems Analyst Organization : Brigham & Women's Hospital(BWH) Schedule : Full-time Standard Hours : 40 Shift : Day Job Employee Status : Regular Recruiting Department : BWH Department Of Medicine Job Posting : Apr 17, 2018[Click Here to Access the Original Job Post]
The bioinformatician will play a central role in the management and analysis of single cell genomic data at the new Chromium 10X core facility at Brigham and Women’s Hospital. The core facility will run cutting edge experiments on single cell data, including but not limited to single cell RNA-seq, antibody oligo tagging for protein quantification, TCR and BCR sequencing for repertoire analysis, and multiplexed droplet experiments. The bioinformatician will have the opportunity to contribute scientifically to the implementation and testing novel algorithms, the development of specialized software and high throughput analysis pipelines, and the collaborative analysis of genomic and clinical data with senior scientists from Brigham and Women’s Hospital, Harvard Medical School, The Broad Institute, and the Dana Farber Cancer Institute. The bioinformatician will work closely with Dr. Soumya Raychaudhuri, senior scientists from the Harvard Medical School immunogenomics lab, as well as with outside collaborators. The bioinformatician will have access to computational resources from Partners Healthcare and the Broad Institute. Much of this role is flexible and can suit the talents and interests of capable scientists and engineers. PRINCIPAL DUTIES AND RESPONSIBILITIES: 1.Manage the storage, access, and dissemination of large amounts of data. 2.Develop robust computational pipelines for automated processing of single cell genomic data. 3.Implement and test novel algorithms from scientific literature. 4.Documentation of computational procedures and analyses for reproducible research. 5.Regularly communicate with lab members, collaborators, and technical staff from related core facilities. 6.In collaboration with senior scientific staff, initiate and foster scientific collaborations outside the lab. 7. All other duties as assigned. QUALIFICATIONS: Education:
- MSc or PhD degree in appropriate technical, scientific, or engineering discipline (preferably bioinformatics, computational genomics, or computer science) preferred and at least 2-years experience in a data science driven field.
- Strong programming skills capable of conceiving, of implementing and optimizing programs operating on large data sets.
- Strong written and oral communication skills.
- Unix environment experience; experience with large data sets, database software experience.
- Proficiency in a programming language, such as Java, C/C++, or python and one or more mathematical languages, such as R or MATLAB.
- Experience with bioinformatics and transcriptomic analysis, particularly with single cell RNA-seq data.
- Experience working in an interdisciplinary environment and communicating technical ideas to a wide audience.
- Experience in machine learning and statistical modeling.
- Experience with software engineering and numerical programming.
- Advanced knowledge of biostatistics and statistical programming.
- Formal knowledge in Biology in general; genetics in particular.
- Problem solving and organizational ability; written and interpersonal and communication skills.
- Ability to work independently as well as collaboratively on research teams.
- Must be able to logically and effectively structure tasks and set priorities.
- Ability to identify potential problems and trouble-shoot solutions.
Requeriments :
Skills :
- Bioinformatics
- Biology
- Biostatistics
- Genetics
- Lunix/Unix
- Machine Learning
- Modeling
- Programing in C
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in Java
- Programming in Matlab
- Programming in R
- RNA-seq
- Software Design
- Statistics
- Transcriptomics
Areas :
Additional Info:
EEO Statement Brigham and Women’s Hospital is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, sexual orientation, protected veteran status, or on the basis of disability. Primary Location : MA-Boston-BWH Longwood Medical Area Work Locations : BWH Longwood Medical Area 75 Francis Street Boston 02115 Job : Business and Systems Analyst Organization : Brigham & Women's Hospital(BWH) Schedule : Full-time Standard Hours : 40 Shift : Day Job Employee Status : Regular Recruiting Department : BWH Department Of Medicine Job Posting : Apr 17, 2018[Click Here to Access the Original Job Post]