Senior Bioinformatics Engineer

Job Description:
The Simons Foundation in New York City is seeking a Senior Bioinformatics Engineer to develop and support whole exome sequencing and genome sequencing data analysis pipelines in both research and operational modalities. This position will report to the director of data and analytics in the informatics group and will work with other engineers and analysts in the informatics group, as well as with clinical and basic research teams at the foundation.

Main Functions and Responsibilities:

• Design, develop and operate computational pipelines for next generation sequencing data.
• Work on both large-scale projects and small custom tasks that span a wide variety of analysis problems
• Develop new and/or improve upon existing algorithms for variant detection (SNPs and indels) and structural variant detection (CNVs, inversions and translocations) for clinical research purposes.
• Develop and maintain a knowledge base of variants and annotations discovered in processing of samples

Qualifications

Required:

• Doctoral degree in bioinformatics, computational sciences or related field.
• Over five years’ work experience in bioinformatics
• Experience with next-generation sequencing data
• Experience in Linux/Unix cluster environment
• Advanced programming skills in Python/Java
• Strong background in algorithm development, statistical methods, machine learning and distributed computing.
• Extensive knowledge of computational genomics and experience with high-throughput data analysis
• Outstanding personal initiative and the ability to work effectively as part of a team
• Excellent verbal and written communication skills

Desirable:

• Familiarity with C++, Perl, Matlab and R
• Familiarity with databases—relational and noSQL—cloud computing and web services

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Requeriments :

• Doctorate Degree

Skills :

• Bioinformatics
• Bioinformatics Databases
• Cloud Computing
• genomic
• Lunix/Unix
• Machine Learning
• Next Generation Sequencing
• NoSQL
• Programing in C++
• Programing in Python
• Programing Skills
• Programming in Java
• Programming in Matlab
• Programming in PERL
• Programming in R
• Statistics

Areas :

• Bioinformatics

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Additional Info:
The Simons Foundation is an Equal Opportunity Employer, M/F/D/V.

The Simons Foundation is a private foundation established in 1994 in New York City by Jim and Marilyn Simons. With an annual grants and programs budget of $300 million, the foundation’s mission is to advance the frontiers of research in mathematics and the basic sciences.

The foundation pursues its mission through its grant-making division, comprising programs in Mathematics & Physical Sciences, Life Sciences, Education & Outreach and autism research, and through its internal research division, the Flatiron Institute.

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