Job Description:
Alexion is seeking a talented Senior Data Scientist who is well-versed in analyzing bioinformatics and other kinds of data, including NGS, EMR and other rare disease-related structured and unstructured datasets, and will provide support to all programs and phases in R&D. The position will be a member of the Data Science, Genomics, and Bioinformatics team that are focused on target identification/validation, patient identification/segmentation, genomics/genetics interpretation, creating/navigating disease landscapes, and integrating data across multiple domains including R&D data, clinical trials and health data, patient data, and business intelligence data. The position requires close interaction with scientific teams to generate and test data-driven hypotheses, involving advanced experimental data and working on R&D projects that will make a real difference for patients with rare diseases. The candidate should have a solid foundation in mathematics, statistics, software development and genetics, a strong work ethic, and strong communication and collaborative skills. The successful candidate will have strong programming and statistical skills, a deep understanding of life-sciences databases and search engines, algorithm development, machine learning, visualization tools, and the ability to quickly create research-grade programs and scripts. Principal Responsibilities:
Additional Info:
Boston, MA, United States No Selection Some opportunities happen only once in a lifetime – like a job where you have the extraordinary opportunity to change lives. At Alexion, such opportunities arise through our unwavering mission to serve patients and families affected by rare diseases. These patients are our guiding star, and we act with integrity, urgency, and discipline because we know their lives are at stake. Alexion is a multinational biopharmaceutical company with approximately 2,500 dedicated employees serving patients in more than 50 countries through the innovation, development, and commercialization of life-changing therapies. As the global leader in complement biology, Alexion developed and commercializes the first and only approved complement inhibitor to treat patients with paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG). In addition, Alexion has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D). Our research efforts focus on novel molecules and targets in the complement cascade, and our development efforts focus on our core therapeutic areas of hematology, nephrology, neurology, and metabolic disorders. Alexion’s aspiration is to be the most rewarding place to work, where people are empowered to make a difference and where diversity of backgrounds and ideas is encouraged. We are looking for talented individuals who share our passion and commitment to change the lives of patients with rare diseases. We hope you will consider joining our team. As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Alexion, please visit www.alexion.com. Alexion is an Equal Opportunity /Affirmative action employer[Click Here to Access the Original Job Post]
Alexion is seeking a talented Senior Data Scientist who is well-versed in analyzing bioinformatics and other kinds of data, including NGS, EMR and other rare disease-related structured and unstructured datasets, and will provide support to all programs and phases in R&D. The position will be a member of the Data Science, Genomics, and Bioinformatics team that are focused on target identification/validation, patient identification/segmentation, genomics/genetics interpretation, creating/navigating disease landscapes, and integrating data across multiple domains including R&D data, clinical trials and health data, patient data, and business intelligence data. The position requires close interaction with scientific teams to generate and test data-driven hypotheses, involving advanced experimental data and working on R&D projects that will make a real difference for patients with rare diseases. The candidate should have a solid foundation in mathematics, statistics, software development and genetics, a strong work ethic, and strong communication and collaborative skills. The successful candidate will have strong programming and statistical skills, a deep understanding of life-sciences databases and search engines, algorithm development, machine learning, visualization tools, and the ability to quickly create research-grade programs and scripts. Principal Responsibilities:
- Design and Implement novel machine learning workflows and algorithms on unstructured, disparate data sets
- Develop software tools and scripts at scale to support data analysis and interpretation pipelines.
- Present and discuss findings with project teams, support iterative solutions development and scientific research.
- Integrate and summarize large-scale data and information across multiple scientific, translational, and clinical domains.
- Communicates effectively with team members, experts and regulatory authorities.
- Proven experience in software development such as Java, Python, C/C++, etc.
- Expert knowledge of statistical analysis packages like R, Matlab or Mathematica
- Expert knowledge in probabilistic modeling and simulation
- Expert knowledge of database architecture and design in both SQL and NoSQL varieties
- Experience managing large-scale genomic data and familiarity with public genomic datasets like ExAC, 1000 Genomes, ClinVar, etc.
- Proficient in state of the art data science and machine learning methods and tools
- The qualified applicant must also be flexible, well-organized, and have the ability to work well under pressure.
- Excellent communication and presentation skills with specific experience in cross functional collaborations.
- Problem solving and creativity skills.
Requeriments :
Skills :
- Bioinformatics
- Database design
- Genetics
- genomic
- Machine Learning
- Mathematics
- Modeling
- Next Generation Sequencing
- NoSQL
- Programing in C
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in Java
- Programming in Matlab
- Programming in R
- Software Design
- SQL
- Statistics
Areas :
Additional Info:
Boston, MA, United States No Selection Some opportunities happen only once in a lifetime – like a job where you have the extraordinary opportunity to change lives. At Alexion, such opportunities arise through our unwavering mission to serve patients and families affected by rare diseases. These patients are our guiding star, and we act with integrity, urgency, and discipline because we know their lives are at stake. Alexion is a multinational biopharmaceutical company with approximately 2,500 dedicated employees serving patients in more than 50 countries through the innovation, development, and commercialization of life-changing therapies. As the global leader in complement biology, Alexion developed and commercializes the first and only approved complement inhibitor to treat patients with paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG). In addition, Alexion has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D). Our research efforts focus on novel molecules and targets in the complement cascade, and our development efforts focus on our core therapeutic areas of hematology, nephrology, neurology, and metabolic disorders. Alexion’s aspiration is to be the most rewarding place to work, where people are empowered to make a difference and where diversity of backgrounds and ideas is encouraged. We are looking for talented individuals who share our passion and commitment to change the lives of patients with rare diseases. We hope you will consider joining our team. As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Alexion, please visit www.alexion.com. Alexion is an Equal Opportunity /Affirmative action employer[Click Here to Access the Original Job Post]