Job ID:
Job date: 2018-05-14
End Date: 2018-07-13
Company : TESARO Inc Country : United States Role : Research Scientist
Job date: 2018-05-14
End Date: 2018-07-13
Company : TESARO Inc Country : United States Role : Research Scientist
Job Description:
The Senior Scientist, Computational Biology will provide experienced organizational, technological and scientific leadership in the application of state of the art computational biology and bioinformatics approaches in drug and biomarker development. A crucial component will be the establishment of a high quality and collaborative expertise in data mining, text mining, data analysis, data visualization, computer programming, and computational biology applied across the TESARO portfolio. Responsibilities:
Additional Info:
TESARO is an oncology-focused biopharmaceutical company dedicated to improving the lives of patients with cancer. Our team of passionate associates develops and will commercialize safer and more effective supportive care agents and therapeutics. We take our responsibility to patients seriously. TESARO is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Primary Location: US-MA-Waltham Work Locations: US-Waltham 1000 Winter St Waltham 02451 Job: Research & Development Organization: TESARO US BU Schedule: Full-time Employee Status: Regular Job Type: Standard Job Level: Manager without Direct Reports Job Posting: Apr 18, 2018, 1:41:36 PM[Click Here to Access the Original Job Post]
The Senior Scientist, Computational Biology will provide experienced organizational, technological and scientific leadership in the application of state of the art computational biology and bioinformatics approaches in drug and biomarker development. A crucial component will be the establishment of a high quality and collaborative expertise in data mining, text mining, data analysis, data visualization, computer programming, and computational biology applied across the TESARO portfolio. Responsibilities:
- Access, analyze and integrate publicly available oncogenomic information to enable preclinical experimental design for research teams.
- Work with external resources to generate and analyze tumor genome / transcriptome profiling data for pre-clinical models; integrate with internal and external large scale non-clinical and clinical data sets to understand mechanism of compound response, aimed to inform additional patient selection / enrichment marker development, additional indications, and rational combination strategies.
- Interact effectively with project teams across the portfolio. Develop and manage informatics platform to integrate external and internally acquired data in a format amenable to use by scientists from research, translational and medical development group across the portfolio in the organization.
- Provide support in advanced new asset diligence from cancer informatics perspectives: integrate cancer genomic data to help evaluating new targets and agents.
- PhD degree or equivalent computational / statistical experience / training with 3+ years of applied experience in Pharma/Biotech or academic setting; oncology and oncogenomics preferred
- A high level of integrity and desire to find new medicines that bring benefit to patients; a strong intellectual curiosity and desire to understand and solve problems
- Proven ability to collaborate and influence across multi-disciplinary teams of internal colleagues and interact with external experts in academic institutions as well as CROs
- Experience in large scale, multi-dimensional genomic (including but not limited to NGS) data analysis, integration and management
- Proficient in data visualization and communication with multi-disciplinary team
- Ability to adapt and apply leading algorithms from academic and industry
- Creative and practical use of systems biology methods in gene/target discovery, interpretation of cellular processes, and biomarker discovery.
Requeriments :
Skills :
- Biomarker Discovery
- Data Mining
- genomic
- Next Generation Sequencing
- Programing Skills
- Statistics
- Systems Biology
Areas :
Additional Info:
TESARO is an oncology-focused biopharmaceutical company dedicated to improving the lives of patients with cancer. Our team of passionate associates develops and will commercialize safer and more effective supportive care agents and therapeutics. We take our responsibility to patients seriously. TESARO is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Primary Location: US-MA-Waltham Work Locations: US-Waltham 1000 Winter St Waltham 02451 Job: Research & Development Organization: TESARO US BU Schedule: Full-time Employee Status: Regular Job Type: Standard Job Level: Manager without Direct Reports Job Posting: Apr 18, 2018, 1:41:36 PM[Click Here to Access the Original Job Post]