Job ID: 3129
Job date: 2015-04-07
End Date:
Company : Johnson & Johnson Country : Role : Research Scientist
Job date: 2015-04-07
End Date:
Company : Johnson & Johnson Country : Role : Research Scientist
Job Description:
Senior Scientist, Computational Biology, Biomarkers-1971150324
Description
Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist position, located in Spring House, PA.
Janssen Research & Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive medicine.
Janssen Pharmaceuticals, Inc., a pharmaceutical company of Johnson & Johnson, provides medicines for an array of health concerns in several therapeutic areas, including: attention deficit hyperactivity disorder (ADHD), cardiovascular disease, general medicine (acid reflux disease, infectious diseases), mental health (bipolar I disorder, schizophrenia), neurologics (Alzheimer’s disease, epilepsy, migraine prevention and treatment), pain management, and women’s health. Our ultimate goal is to help people live healthy lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market – from patients to practitioners, from clinics to hospitals. For more about Janssen Pharmaceuticals, Inc., one of the Pharmaceutical Companies of Johnson & Johnson, visit www.janssenpharmaceuticalsinc.com.
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.
The Senior Scientist will work within the Systems Pharmacology & Biomarker (SP&B) department to develop and implement strategies to identify and validate novel biomarkers for investigational therapies in the application of disease understanding, response prediction, and patient stratification. The successful candidate will be highly motivated; be able to interface with internal (Discovery, Disease Integrated Biology and Clinical) and external partners; and be responsible for maintaining a state-of-the-art knowledge in computational biology methodologies to support biomarker initiatives. The position will require performing analysis of multidimensional high content data sets, integrating these data sets with clinical metadata, assessing novel correlations across multiple parameters to test biological hypotheses and identify novel biomarkers.
.
Qualifications
Ph.D. with at least 5 years of relevant experience OR a MS with at least 8 years of relevant industry experience is required
Qualified candidates must have relevant experience in Computational Biology, Immunology, Statistics, Network Pharmacology / Systems Biology, Bioinformatics or related field
Experience with high content data analysis, such as RNAseq, whole genome sequencing, microbiome and proteomic data is required
Familiarity with human translational research, clinical trial metadata, and experience with predictive models and diagnostics is expected
The candidate must have a current knowledge of the scientific literature and strong communication skills
Ability to perform data QC and interface with internal wet laboratory and external data generation providers and scientific collaborators to ensure quality and compliance with appropriate internal policies is a required
Strong statistical skills and experience with large datasets (gene expression, proteomic data, and NGS), predictive models and diagnostics, network analysis, and clinical trial data are required
Proficiency in standard analytical platforms (e.g., R, SAS, Matlab, Omicsoft ArrayStudio, as well as, gene set enrichment and pathway analysis software tools (e.g.GSEA/GSVA, Thomson-Reuters GeneGo, Ingenuity, Cytoscape, etc.) is required
Strong communication (written and oral presentation) and organization skills, and ability to handle multiple projects simultaneously are essential
Expertise in predictive algorithms and experience in biomarker discovery and/or co-diagnostic development for pharmaceutical applications is strongly preferred
Knowledge of rheumatoid arthritis, autoimmune disease, immunology, biomarker discovery and an understanding of relevant published literature is preferred
BE VITAL in your career, Be seen for the talent you bring to your work. Explore opportunities within the Johnson & Johnson Family of Companies
J2W: BIO
Primary Location: North America-United States-Pennsylvania-Spring House
Organization: Janssen Research & Development, LLC. (6084)
Job Function: Biology
Certain sites within the Johnson & Johnson Family of Companies participate in E-Verify as appropriate in accordance with Company guidelines and federal or state law. To learn more about the government sponsored program and to see a list of the sites that are currently enrolled, please click here.
Johnson and Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.
EEO is the Law
EEO is the Law GINA Supplement
Additional Info:
[Click Here to Access the Original Job Post]
Senior Scientist, Computational Biology, Biomarkers-1971150324
Description
Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist position, located in Spring House, PA.
Janssen Research & Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive medicine.
Janssen Pharmaceuticals, Inc., a pharmaceutical company of Johnson & Johnson, provides medicines for an array of health concerns in several therapeutic areas, including: attention deficit hyperactivity disorder (ADHD), cardiovascular disease, general medicine (acid reflux disease, infectious diseases), mental health (bipolar I disorder, schizophrenia), neurologics (Alzheimer’s disease, epilepsy, migraine prevention and treatment), pain management, and women’s health. Our ultimate goal is to help people live healthy lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market – from patients to practitioners, from clinics to hospitals. For more about Janssen Pharmaceuticals, Inc., one of the Pharmaceutical Companies of Johnson & Johnson, visit www.janssenpharmaceuticalsinc.com.
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.
The Senior Scientist will work within the Systems Pharmacology & Biomarker (SP&B) department to develop and implement strategies to identify and validate novel biomarkers for investigational therapies in the application of disease understanding, response prediction, and patient stratification. The successful candidate will be highly motivated; be able to interface with internal (Discovery, Disease Integrated Biology and Clinical) and external partners; and be responsible for maintaining a state-of-the-art knowledge in computational biology methodologies to support biomarker initiatives. The position will require performing analysis of multidimensional high content data sets, integrating these data sets with clinical metadata, assessing novel correlations across multiple parameters to test biological hypotheses and identify novel biomarkers.
.
Qualifications
Ph.D. with at least 5 years of relevant experience OR a MS with at least 8 years of relevant industry experience is required
Qualified candidates must have relevant experience in Computational Biology, Immunology, Statistics, Network Pharmacology / Systems Biology, Bioinformatics or related field
Experience with high content data analysis, such as RNAseq, whole genome sequencing, microbiome and proteomic data is required
Familiarity with human translational research, clinical trial metadata, and experience with predictive models and diagnostics is expected
The candidate must have a current knowledge of the scientific literature and strong communication skills
Ability to perform data QC and interface with internal wet laboratory and external data generation providers and scientific collaborators to ensure quality and compliance with appropriate internal policies is a required
Strong statistical skills and experience with large datasets (gene expression, proteomic data, and NGS), predictive models and diagnostics, network analysis, and clinical trial data are required
Proficiency in standard analytical platforms (e.g., R, SAS, Matlab, Omicsoft ArrayStudio, as well as, gene set enrichment and pathway analysis software tools (e.g.GSEA/GSVA, Thomson-Reuters GeneGo, Ingenuity, Cytoscape, etc.) is required
Strong communication (written and oral presentation) and organization skills, and ability to handle multiple projects simultaneously are essential
Expertise in predictive algorithms and experience in biomarker discovery and/or co-diagnostic development for pharmaceutical applications is strongly preferred
Knowledge of rheumatoid arthritis, autoimmune disease, immunology, biomarker discovery and an understanding of relevant published literature is preferred
BE VITAL in your career, Be seen for the talent you bring to your work. Explore opportunities within the Johnson & Johnson Family of Companies
J2W: BIO
Primary Location: North America-United States-Pennsylvania-Spring House
Organization: Janssen Research & Development, LLC. (6084)
Job Function: Biology
Certain sites within the Johnson & Johnson Family of Companies participate in E-Verify as appropriate in accordance with Company guidelines and federal or state law. To learn more about the government sponsored program and to see a list of the sites that are currently enrolled, please click here.
Johnson and Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.
EEO is the Law
EEO is the Law GINA Supplement
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]