Senior Scientist – Guardant Health – Redwood City, CA

Job ID: 5731
Job date: 2016-07-08
End Date:

Company : Guardant Health 

Country :

Role : Research Scientist 


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Job Description:
ABOUT THE ROLE

To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Research Scientist to help test and validate novel technologies for rare variant studies with next-generation sequencing in a regulated environment. At Guardant, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.

As a Research Scientist in the Technology Development Team, you will work with members within the team and interface with multiple teams including process engineering, clinical operations, research operations, and bioinformatics. You will be hands on in the lab and be required to design, implement, and validate new technologies related to liquid biopsy sequencing assays for the early detection, treatment, and monitoring of all cancer types.

RESPONSIBILITIES

Be able to work in a team environment and independently to develop, test and validate technologies for rare variant studies with next-generation sequencing Think creatively and apply knowledge to design validation experiments and analyze data for NGS applications in oncology diagnostics Document product development requirements and validation results Be highly committed and deliver results in a fast-paced start-up environment DESIRED SKILLS & EXPERIENCE

Be able to work in a team environment and independently to develop, test and validate technologies for rare variant studies with next-generation sequencing Think creatively and apply knowledge to design validation experiments and analyze data for NGS applications in oncology diagnostics Document product development requirements and validation results Be highly committed and deliver results in a fast-paced start-up environment 5+ years of experience in genomics or molecular biology, preferably developing IVDs Experience with development under a FDA regulated environment (i.e. Design control) is a plus Experience optimizing a developing droplet digital PCR is a plus Comprehensive knowledge of sample preparation and sequencing technologies Strong background in molecular biology Experience in development or optimization of nucleic acid technologies with a strong preference related to sequencing-based genomic assays, preferably in regulated environments. Deep technical knowledge of NGS library preparation, target enrichment, and rigorous product development practices Experience with bioinformatics analysis of NGS data Excellent interdisciplinary communication skills required Good organization skills, and detailed orientated Self-driven and strong team player with proven track record EDUCATION

PhD in Molecular Biology, Genetics, Biochemistry or related field Strong preference given to local candidates ABOUT OUR COMPANY

Guardant Health develops breakthrough diagnostic technologies to improve cancer management. With Guardant360, we offer real-time, biopsy-free tumor sequencing that tracks tumor genomics in real-time and identifies associated treatment options. The recent introduction of groundbreaking analytical tools, including our Tumor Response Map and a mobile-enabled physician portal, further advance Guardant Health's momentum.

Guardant Health has raised almost $200M from OrbiMed, Sequoia Capital, Khosla Ventures, Lightspeed Venture Partners, and Formation8, and is led by a seasoned management team of thought leaders and successful serial entrepreneurs in next generation sequencing and rare cell diagnostics. They are advised by an oncologist-led medical steering committee from leading cancer centers.


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