Job Description:
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader to develop and market advanced therapies that address some of the world’s most complex and serious diseases. In 2013, AbbVie employs approximately 21,000 people worldwide and markets medicines in more than 170 countries.
We seek a highly motivated scientist in Structural Bioinformatics with a proven track record of accomplishment to further develop our cutting-edge dual/multi-specific and other “fit-for-purpose” antibody technologies. This individual will develop/modify/run software tools required for analysis of protein aggregation/stability and conformational characterization.
He/she will work with cross-disciplinary teams both internally and externally for protein design, engineering, characterization, and formulation study, and for improving protein design quality and enhancing capacity/through put of current in silico tools. The candidate is expected to coordinate and make substantial contributions to the conceptualization/theorization, execution and communication of protein design and engineering projects.
Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Qualifications
Basic:
•Requirements for this position include a PhD or equivalent experience plus post-doctoral training in Computational Chemistry/Biology/Physics, or alternatively in Biological Sciences with relevant experience in protein computational analysis, or Structural Bioinformatics.
•The incumbent should have significant experience in protein therapeutics and have a thorough understanding of molecular and structural basis for protein stability and solubility, and domain/domain interaction, is familiar with cutting-edge toolsfor protein structural biology study.
•Well-qualified candidates will have extensive research experience using computational and/or statistical approaches to address biological problems, including bioinformatics and/or sequence/structure prediction.
•Applicants should be well-versed in biology, yet proficient in computer science and mathematics.
•It is expected that the applicant will have demonstrated a sustained record of productivity and impactful scientific contributions as determined by publications in high-impact journals.
•The ideal candidate will have a background combining computational with some wet lab research.
•Programming expertise and experience writing new software are highly valued.
•Research experience with antibodies and multi-specific biologics is preferred but not essential.
•Strong inter-personal and communication skills are needed for this role.
•Highly motivated candidates with a passion for innovation are particularly encouraged to apply.
Significant Work Activities and Conditions Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day), Continuous standing for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Job Classification
: Experienced
Job
: RESEARCH AND DEVELOPMENT
Primary Location
: USA-Massachusetts-Worcester
Organization
: GPRD-Pharma R&D
Schedule
: Full-time
Shift: Day
Travel
: Yes, 10 % of the Time
Additional Info:
[Click Here to Access the Original Job Post]
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader to develop and market advanced therapies that address some of the world’s most complex and serious diseases. In 2013, AbbVie employs approximately 21,000 people worldwide and markets medicines in more than 170 countries.
We seek a highly motivated scientist in Structural Bioinformatics with a proven track record of accomplishment to further develop our cutting-edge dual/multi-specific and other “fit-for-purpose” antibody technologies. This individual will develop/modify/run software tools required for analysis of protein aggregation/stability and conformational characterization.
He/she will work with cross-disciplinary teams both internally and externally for protein design, engineering, characterization, and formulation study, and for improving protein design quality and enhancing capacity/through put of current in silico tools. The candidate is expected to coordinate and make substantial contributions to the conceptualization/theorization, execution and communication of protein design and engineering projects.
Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Qualifications
Basic:
•Requirements for this position include a PhD or equivalent experience plus post-doctoral training in Computational Chemistry/Biology/Physics, or alternatively in Biological Sciences with relevant experience in protein computational analysis, or Structural Bioinformatics.
•The incumbent should have significant experience in protein therapeutics and have a thorough understanding of molecular and structural basis for protein stability and solubility, and domain/domain interaction, is familiar with cutting-edge toolsfor protein structural biology study.
•Well-qualified candidates will have extensive research experience using computational and/or statistical approaches to address biological problems, including bioinformatics and/or sequence/structure prediction.
•Applicants should be well-versed in biology, yet proficient in computer science and mathematics.
•It is expected that the applicant will have demonstrated a sustained record of productivity and impactful scientific contributions as determined by publications in high-impact journals.
•The ideal candidate will have a background combining computational with some wet lab research.
•Programming expertise and experience writing new software are highly valued.
•Research experience with antibodies and multi-specific biologics is preferred but not essential.
•Strong inter-personal and communication skills are needed for this role.
•Highly motivated candidates with a passion for innovation are particularly encouraged to apply.
Significant Work Activities and Conditions Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day), Continuous standing for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Job Classification
: Experienced
Job
: RESEARCH AND DEVELOPMENT
Primary Location
: USA-Massachusetts-Worcester
Organization
: GPRD-Pharma R&D
Schedule
: Full-time
Shift: Day
Travel
: Yes, 10 % of the Time
Requeriments :
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]