Job ID: 10900
Job date: 2017-02-25
End Date:
Company : Takeda Pharmaceuticals Country : Role : Research Scientist
Job date: 2017-02-25
End Date:
Company : Takeda Pharmaceuticals Country : Role : Research Scientist
Job Description:
Based in Cambridge, MA, the role is a computational biologist who will apply computational solutions for integrative analysis of Omics data in the ongoing efforts to make contributions in (1) gaining mechanistic insights into the effect of drug treatment, (2) target and biomarker discovery, (3) indication and patient population selection and (4) building clinical development strategy. ACCOUNTABILITIES: -Acts as an expert consultant and scientific resource for others in the organization based on extensive knowledge from within own discipline -Collaborates with others, and acts as scientific resource for an aspect of a program. -Contributes to team problem resolution and objective setting. Interprets complex biological information to perform tasks to reduce and consolidate output from various databases. -Prepares data for utilization by other scientists. -Is responsible for the analysis of both pre-clinical and clinical data sets including RNA-Seq, Exome and Whole Genome Sequencing, single cell sequencing and high throughput proteomics to nominate novel drug targets, enable patient enrichment strategies, and prioritize combination therapies. -Monitors and queries new data from both internal and public databases to satisfy quality control criteria. -Writes reports, initiates and reviews documentation. Conducts scientific presentations for internal/external audiences. -Contributes to the authorship of scientific manuscripts, frequently as principal author. -Contributes strategic scientific guidance to company patent efforts. Qualifications EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS: -PhD in Bioinformatics, Computational Biology with a minimum of 5 years experience or equivalent. -Demonstrated experience with large-scale Omics and highthoughput data analysis, network analysis, and meta-analyses. Familiar with public domain data sources. -Experience in algorithm generation and/or computational method implementation. -Strong scientific understanding of molecular biology and genomics. Working knowledge with bioinformatics studies of Immunogenomics, is highly desirable. -Proven track record of driving a significant scientific or technological project to success. -Solid understanding of fundamental Systems Biology concepts. Strong data analysis and troubleshooting skills. -Mastery of unix/linux, and fluency in at least one programming language (e.g., Phython, Perl, Java, C / C++). -Strong knowledge in statistical software and language (e.g., R, SAS, matlab). -Familiarity with parallel computing, database (e.g., SQL) and Amazon Web Services. -Ability to think strategically, and work effectively in a matrix organization -Excellent communication, presentation, and interpersonal skills. TRAVEL REQUIREMENTS: Requires approximately <10% or more travel, including international.
Additional Info:
More than 30,000 Takeda employees working in more than 70 countries are committed to improving quality of life for patients, who remain at the center of everything we do. Takeda Pharmaceutical Company Limited is a global, research and development-driven organization working internally and with external partners to translate science into life-changing medicines. Takeda focuses on the core therapeutic areas of oncology, gastroenterology, central nervous system and providing vaccines that address the most important infectious diseases. Novel products, especially in oncology and gastroenterology, as well as our presence in emerging markets, fuel our growth. Takeda Pharmaceuticals U.S.A., Inc. ranks among the top 15 pharmaceutical companies in the United States. Our larger U.S. offices are in Cambridge, MA, Deerfield, IL, and San Diego, CA. Research & Development employees in our Cambridge location focus on oncology, gastroenterology, immunomodulation, biologics, translational research, and external innovation. In March 2016, we opened our newest space at 300 Massachusetts Avenue, featuring 230,000 square feet of state-of-the-art office and lab space. While Takeda is enjoying tremendous growth as an emerging global leader in the pharmaceutical industry, we remain ever mindful of our commitment to serve people worldwide by striving toward better health through leading innovation in medicine. In short, we are a passionate team doing important work that impacts patients’ lives. If you are driven to create better health and a brighter future, join us! we are driven to improve people's lives www.takedajobs.com Takeda is an EEO employer of minorities, women, disabled, protected veterans, and considers qualified applicants with criminal histories in accordance with applicable laws. For more information, visithttp://www.takeda.us/careers/EEO_Policy_Statement.aspx No Phone Calls or Recruiters Please. [Click Here to Access the Original Job Post]
Based in Cambridge, MA, the role is a computational biologist who will apply computational solutions for integrative analysis of Omics data in the ongoing efforts to make contributions in (1) gaining mechanistic insights into the effect of drug treatment, (2) target and biomarker discovery, (3) indication and patient population selection and (4) building clinical development strategy. ACCOUNTABILITIES: -Acts as an expert consultant and scientific resource for others in the organization based on extensive knowledge from within own discipline -Collaborates with others, and acts as scientific resource for an aspect of a program. -Contributes to team problem resolution and objective setting. Interprets complex biological information to perform tasks to reduce and consolidate output from various databases. -Prepares data for utilization by other scientists. -Is responsible for the analysis of both pre-clinical and clinical data sets including RNA-Seq, Exome and Whole Genome Sequencing, single cell sequencing and high throughput proteomics to nominate novel drug targets, enable patient enrichment strategies, and prioritize combination therapies. -Monitors and queries new data from both internal and public databases to satisfy quality control criteria. -Writes reports, initiates and reviews documentation. Conducts scientific presentations for internal/external audiences. -Contributes to the authorship of scientific manuscripts, frequently as principal author. -Contributes strategic scientific guidance to company patent efforts. Qualifications EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS: -PhD in Bioinformatics, Computational Biology with a minimum of 5 years experience or equivalent. -Demonstrated experience with large-scale Omics and highthoughput data analysis, network analysis, and meta-analyses. Familiar with public domain data sources. -Experience in algorithm generation and/or computational method implementation. -Strong scientific understanding of molecular biology and genomics. Working knowledge with bioinformatics studies of Immunogenomics, is highly desirable. -Proven track record of driving a significant scientific or technological project to success. -Solid understanding of fundamental Systems Biology concepts. Strong data analysis and troubleshooting skills. -Mastery of unix/linux, and fluency in at least one programming language (e.g., Phython, Perl, Java, C / C++). -Strong knowledge in statistical software and language (e.g., R, SAS, matlab). -Familiarity with parallel computing, database (e.g., SQL) and Amazon Web Services. -Ability to think strategically, and work effectively in a matrix organization -Excellent communication, presentation, and interpersonal skills. TRAVEL REQUIREMENTS: Requires approximately <10% or more travel, including international.
Requeriments :
Skills :
- Biomarker Discovery
- genomic
- Lunix/Unix
- molecular biology
- Parallel Computing
- Programing in C
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in Java
- Programming in Matlab
- Programming in PERL
- Programming in SAS
- RNA-seq
- SQL
- Systems Biology
Areas :
Additional Info:
More than 30,000 Takeda employees working in more than 70 countries are committed to improving quality of life for patients, who remain at the center of everything we do. Takeda Pharmaceutical Company Limited is a global, research and development-driven organization working internally and with external partners to translate science into life-changing medicines. Takeda focuses on the core therapeutic areas of oncology, gastroenterology, central nervous system and providing vaccines that address the most important infectious diseases. Novel products, especially in oncology and gastroenterology, as well as our presence in emerging markets, fuel our growth. Takeda Pharmaceuticals U.S.A., Inc. ranks among the top 15 pharmaceutical companies in the United States. Our larger U.S. offices are in Cambridge, MA, Deerfield, IL, and San Diego, CA. Research & Development employees in our Cambridge location focus on oncology, gastroenterology, immunomodulation, biologics, translational research, and external innovation. In March 2016, we opened our newest space at 300 Massachusetts Avenue, featuring 230,000 square feet of state-of-the-art office and lab space. While Takeda is enjoying tremendous growth as an emerging global leader in the pharmaceutical industry, we remain ever mindful of our commitment to serve people worldwide by striving toward better health through leading innovation in medicine. In short, we are a passionate team doing important work that impacts patients’ lives. If you are driven to create better health and a brighter future, join us! we are driven to improve people's lives www.takedajobs.com Takeda is an EEO employer of minorities, women, disabled, protected veterans, and considers qualified applicants with criminal histories in accordance with applicable laws. For more information, visithttp://www.takeda.us/careers/EEO_Policy_Statement.aspx No Phone Calls or Recruiters Please. [Click Here to Access the Original Job Post]