Sr. Scientist, Next Generation Sequencing : Cambridge, MA, United States

Job Description:
Sr. Scientist, Next Generation Sequencing Position Summary Moderna is seeking an exceptionally talented and highly motivated research scientist with experience in next-generation sequencing (NGS) technologies to lead a highly collaborative, multi-disciplinary, and fast-paced team within the Platform Analytics group. The primary focus for this position is to leverage NGS platforms to analyze a broad range of RNA and DNA samples using various methods. The successful candidate will work with multiple groups across the company to develop and implement state-of-the-art methods using NGS technology.

Responsibilities

• Design and perform complex RNA/DNA sequencing applications, including sample preparation, sequencer library creation, library quantification, and sequencer operation on the Illumina platform
• Increase NGS performance and capacity including: improving data quality, troubleshooting failures, ensuring instrument performance, and reducing the cost of sequencing processes
• Establish and coordinate closely with the Bioinformatics team in to develop appropriate hypotheses and data analysis pipelines and deliver robust, integrated analyses of the NGS data
• Interact regularly and collaborate with cross-functional groups to troubleshoot and resolve complex technical problems impacting the quantity and quality of samples and data
• Maintain up-to-date expertise in the expanding landscape of NGS-based applications and technologies and provide subject matter expertise for groups across the company
• Work collaboratively across all disciplines within the company in order to deliver data against aggressive timelines
• Maintain a clean and safe laboratory work area and ensure compliance to safety policies

Minimum Qualifications

• Ph.D. in life science (Biology, Biochemistry, Molecular Biology, Genetics, or related science) with 2+ years of experience in an industrial setting
• Hands on ? experience utilizing Illumina next generation sequencing platforms and familiarity with issues related to sequence quality and assembly
• Demonstrated experience with multiple RNAseq applications such as: RNAseq, miRNA-seq, RACE, ribosomal profiling, PAR-clip, etc.
• Expertise in a variety of molecular biology methods related to NGS sample prep including ligation, reverse-transcription, and PCR
• Demonstrated ability to perform basic analysis of NGS data files using a command line, high-performance compute environment

Preferred Qualifications

• Experience with both technical project management and direct management of employees and their performance
• Demonstrated expertise in RNA biology and processes impacting mRNAs
• Ability to use and/or modify custom written computer scripts written in Python coding language
• Familiarity with sequence alignment tools such as Bowtie, Cufflinks, and TopHat

Competencies

• Commitment to excellence and innovation
• Effective time management, organization, and planning skills.
• Detail-oriented with strong writing and record-keeping skills.
• Flexibility; adaptability to frequent change
• Scientific rigor
• Self-starter with a can do ? attitude
• Results oriented; ability to manage performance
• Effective communication, both written and verbal
• Personal and shared accountability

Requeriments :

• Doctorate Degree

Skills :

• Bioinformatics
• Next Generation Sequencing
• RNA-seq

Areas :

• Bioinformatics
• Computational Biology

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