Job Description:
To apply for this job Either Download, Save and Complete a copy of the application form using Microsoft Word Or Prepare a copy of your CV that contains all the information requested in the application form Submit your application document (single file in word or acrobat format) together with your Personal details, Referees and Equal Opportunities Monitoring data The Genome Analysis Centre The Genome Analysis Centre (TGAC) is a vibrant, contemporary research institute and registered charity, working in an area of rapid technological development and innovation. TGAC is strategically funded by the BBSRC to lead the development of a skill base in bioinformatics and a genomics technology platform for UK bioscience. The Institute is located on the Norwich Research Park, together with its partners: the John Innes Centre, the Institute of Food Research, The Sainsbury Laboratory, the University of East Anglia and the Norfolk and Norwich University Hospital. The research park has an excellent reputation for research in plant and microbial sciences, interdisciplinary environmental science and food, diet and health, to which TGAC contributes strengths in genomics and bioinformatics. Close links exist between the NRP partners and new opportunities for collaboration in exciting new initiatives are under development. The NRP recently received £26M of government investment to facilitate innovation and further develop infrastructure to attract science and technology companies to the Park to enhance the vibrant environment and realise economic impact from research investment. TGAC is a UK hub for innovative Bioinformatics through research, analysis and interpretation of multiple, complex data sets. It hosts one of the largest computing hardware facilities dedicated to life science research in Europe. This has been boosted recently by an e-Infrastructure grant to expand the data storage capacity to a multi-petabyte unit, deploying a high performance cluster and large-memory server enabling the allocation of processes requiring several terabytes of computing memory. TGAC’s state of the art DNA sequencing facility operates multiple complementary technologies for data generation that provide the foundation for analyses furthering our fundamental understanding of genomes and how they function. We aim to be at the forefront of technological advances and are developing and implementing technologies to generate and analyse new types of data. We also develop novel platforms to provide access to computational tools and processing capacity for multiple academic and industrial users and promoting applications of computational bioscience. TGAC has one fully owned subsidiary, Genome Enterprise Ltd (GEL) via which it offers genomic and bioinformatics services on a trading basis and works with commercial providers on a partnership basis. TGAC also receives specific funding to enable knowledge exchange programmes which are supported across the institute teams. Post Number 1002841 Job Title Platforms & Pipelines Bioinformatics Manager Closing Date 4 Jun 2015 Grade SC4 Starting Salary £42,720 - £50,800 Hours per week 37 Project Title Delivering the BBSRC National Capability in Genomics, providing access to state of the art genomics technologies for research groups. Months Duration Indefinite Main purpose of the job The Platforms and Pipelines (P&P) Group is responsible for delivering the BBSRC National Capability in Genomics, providing access to state of the art genomics technologies for research groups throughout the UK. The P&P Bioinformatics team performs two main functions: data analysis for diverse sequencing platforms and applications and providing bioinformatics support to both internal and external projects. The team are responsible for maintaining process management and tracking systems along with efficient processing and QC of sequence data. For many projects undertaken by TGAC the Institute’s role in data analysis is crucial and the NCG bioinformatics team are expected to provide expert support to both internal and external stakeholders. This will involve a wide variety of analysis including genome assembly, targeted re-sequencing, genotyping, transcriptomics, epigenetics and metagenomics in a range of non-model and model systems. The team leader will be required to oversee the growth of the bioinformatics portfolio of the P&P group as well as support the project management team in delivering expert assessment for project requirements and study design. Building relationships with Science Faculty groups to bring cutting edge tools, resources and analysis techniques to the P&P group will be an essential part of the role. Department Operations Group Details The Genome Analysis Centre is an institute supported by the BBSRC to ensure that biological science in the UK has access to a skill base in genomics technologies and bioinformatics to deliver programmes leading to improved food security, advances in industrial biotechnology and improved human health and wellbeing. The Institute is located on the Norwich Research Park (NRP), together with The Sainsbury Laboratory, the John Innes Centre, and the Institute of Food Research, the University of East Anglia and the Norfolk and Norwich University Hospital. The research park has an excellent reputation for research in plant and microbial sciences, interdisciplinary environmental science and food, diet and health. The NRP recently received £26M government investment for innovation and infrastructure to attract science and technology companies to establish a vibrant environment to realise economic impact from research investment. Capability in DNA sequencing and the integrated use of multiple sequencing technologies to further our fundamental understanding of genomes, and how they function, will be at the heart of our scientific programmes and the work that we undertake in collaboration with other research institutes, universities and industry throughout the UK, and internationally. TGAC actively explores and implements new applications of DNA sequencing technologies and has automated many of the routine laboratory steps to accelerate and ensure high reproducibility of sequence data. The work on data generation will complement TGAC’s growing strengths in bioinformatics analysis and interpretation of multiple, complex data sets and in developing novel platforms to provide access to computational tools and processing capacity for a variety of users. TGAC is a UK hub for innovative bioinformatics and genomics and their applications in a broad spectrum of bioscience. Our mission is to provide a flexible approach to the generation of data from biological systems Advert Text The Genome Analysis Centre (TGAC) has an exciting new role for a Bioinformatics Manager in the Platforms and Pipelines (P&P) group. The successful candidate will lead the P&P Bioinformatics team to drive high-quality data analysis for the BBSRC National Capability in Genomics (NCG), which provides access to state of the art genomics technologies for research groups throughout the UK. This role will oversee two key functions: the strategic development of a broad portfolio of bioinformatics data analyses to be delivered via the P&P Team, as well as delivering high quality primary data analysis and expert bioinformatics support to internal and external customers. The successful candidate will be expected to have a deep understanding of, and interest in, a wide variety of analysis including genome assembly, targeted re-sequencing, genotyping, transcriptomics, epigenetics and metagenomics in a range of non-model and model systems. TGAC is a vibrant, contemporary research institute and a UK hub for innovative Bioinformatics through research, analysis and interpretation of data sets. We hosts one of the largest computing hardware facilities dedicated to life science research in Europe and our aim is to ensure that biological science in the UK has access to a skill base in genomics and bioinformatics to deliver programmes leading to improved food security, advances in industrial biotechnology and improved human health and wellbeing. At TGAC we offer competitive salaries, excellent defined contribution pension scheme, life assurance, tailored learning and development and onsite sports facilities that are available to all staff and their guests. As a user of the disability symbol, we guarantee to interview all disabled applicants who meet the minimum essential criteria for this vacancy. Key relationships Internal: Reporting to the Head of Platforms and Pipelines (P&P), with close liaison with other P&P managers (Project Management and Operations), the Head of Scientific Computing (SC) and Business Development and Communications (BD&C) Groups within the Operations Divisions, as well as all of the Science Faculty. Managing: A team of 3 Bioinformaticians, with additional posts to be recruited. Interacting with: All TGAC staff, and wider collaborators. External: National Capability in Genomics customers and collaborators, industry partners and bioinformatics service and software companies, nationally and internationally. There will also be some interactions with partners on the Norwich Research Park and our shared corporate service provider (NBIP). Main Activities & Responsibilities Facilitating knowledge transfer from TGAC’s Science Faculty so that cutting edge tools and analysis techniques can be deployed as a service. Delivering expert advice on study design to ensure that projects have sufficient power for downstream analysis Providing specialist bioinformatics advice and assistance to stakeholders in troubleshooting bioinformatics analyses. Maintaining excellent current awareness of new analysis protocols and opportunities that can strengthen the P&P bioinformatics portfolio. Developing and extending automation for efficient QC monitoring and primary data processing from a diverse range of platforms (Currently Illumina HiSeq/MiSeq, PacBio, Ion Proton, Oxford Nanopore MinION, Opgen Argus, BioNanoGenomics Irys, but will expand in the future as new technology arises). Overseeing timely, accurate and high-quality completion of projects in collaboration with the P&P Project Management team. Maintain clear communications with those performing library construction and Sequencing to drive process improvement through QC monitoring. Gathering requirements for TGAC’s Software Development team to drive development of laboratory process support systems (MISO LIMS/Atlassian JIRA). Overseeing and performing analysis of genomic data. Cross-training team members to provide essential business continuity. Education & Qualifications Requirement Importance University degree in a relevant discipline (e.g. Computer Science, Software Engineer, bioinformatics). Essential PhD in a relevant discipline, e.g. Computer Science, Software Engineer, Bioinformatics, Biological sciences). Desirable Specialist Knowledge & Skills Requirement Importance Management skills – demonstrated through the management of a team or project. Essential Broad and deep knowledge of computational methods for high-throughput sequence analysis and interpretation. Essential Track record in the development of bioinformatics tools applied to analysis of genomics data. Desirable Demonstrable knowledge of programming languages and database management systems and SQL with a focus on the analysis of large datasets. Desirable Relevant Experience Requirement Importance Extensive experience in delivering bioinformatics as a service. Essential Experience of working in a production customer-focused environment. Essential Experienced manager (management of change, funding and financial sustainability). Essential Experience of working in a high throughput genomics environment with disciplined delivery of high quality data and analysis. Desirable Experience of working with HPC job submission. Desirable Interpersonal & Communication Skills Requirement Importance Demonstrable development of own skills and skills of others. Essential Demonstrable use of innovative approaches and continuous improvement. Essential Able to value others contributions and give others dignity and respect. Essential Good oral and written communications skills. Essential Able to lead and motivate an effective team, and a good team player. Essential Able to demonstrate confidentially in working with a range of customers and collaborators, including industrial partners. Essential Good problem solver, able to logically identify solutions to technical problems. Essential Able to see the bigger picture and contribute towards strategy discussions. Essential
Additional Info:
[Click Here to Access the Original Job Post]
To apply for this job Either Download, Save and Complete a copy of the application form using Microsoft Word Or Prepare a copy of your CV that contains all the information requested in the application form Submit your application document (single file in word or acrobat format) together with your Personal details, Referees and Equal Opportunities Monitoring data The Genome Analysis Centre The Genome Analysis Centre (TGAC) is a vibrant, contemporary research institute and registered charity, working in an area of rapid technological development and innovation. TGAC is strategically funded by the BBSRC to lead the development of a skill base in bioinformatics and a genomics technology platform for UK bioscience. The Institute is located on the Norwich Research Park, together with its partners: the John Innes Centre, the Institute of Food Research, The Sainsbury Laboratory, the University of East Anglia and the Norfolk and Norwich University Hospital. The research park has an excellent reputation for research in plant and microbial sciences, interdisciplinary environmental science and food, diet and health, to which TGAC contributes strengths in genomics and bioinformatics. Close links exist between the NRP partners and new opportunities for collaboration in exciting new initiatives are under development. The NRP recently received £26M of government investment to facilitate innovation and further develop infrastructure to attract science and technology companies to the Park to enhance the vibrant environment and realise economic impact from research investment. TGAC is a UK hub for innovative Bioinformatics through research, analysis and interpretation of multiple, complex data sets. It hosts one of the largest computing hardware facilities dedicated to life science research in Europe. This has been boosted recently by an e-Infrastructure grant to expand the data storage capacity to a multi-petabyte unit, deploying a high performance cluster and large-memory server enabling the allocation of processes requiring several terabytes of computing memory. TGAC’s state of the art DNA sequencing facility operates multiple complementary technologies for data generation that provide the foundation for analyses furthering our fundamental understanding of genomes and how they function. We aim to be at the forefront of technological advances and are developing and implementing technologies to generate and analyse new types of data. We also develop novel platforms to provide access to computational tools and processing capacity for multiple academic and industrial users and promoting applications of computational bioscience. TGAC has one fully owned subsidiary, Genome Enterprise Ltd (GEL) via which it offers genomic and bioinformatics services on a trading basis and works with commercial providers on a partnership basis. TGAC also receives specific funding to enable knowledge exchange programmes which are supported across the institute teams. Post Number 1002841 Job Title Platforms & Pipelines Bioinformatics Manager Closing Date 4 Jun 2015 Grade SC4 Starting Salary £42,720 - £50,800 Hours per week 37 Project Title Delivering the BBSRC National Capability in Genomics, providing access to state of the art genomics technologies for research groups. Months Duration Indefinite Main purpose of the job The Platforms and Pipelines (P&P) Group is responsible for delivering the BBSRC National Capability in Genomics, providing access to state of the art genomics technologies for research groups throughout the UK. The P&P Bioinformatics team performs two main functions: data analysis for diverse sequencing platforms and applications and providing bioinformatics support to both internal and external projects. The team are responsible for maintaining process management and tracking systems along with efficient processing and QC of sequence data. For many projects undertaken by TGAC the Institute’s role in data analysis is crucial and the NCG bioinformatics team are expected to provide expert support to both internal and external stakeholders. This will involve a wide variety of analysis including genome assembly, targeted re-sequencing, genotyping, transcriptomics, epigenetics and metagenomics in a range of non-model and model systems. The team leader will be required to oversee the growth of the bioinformatics portfolio of the P&P group as well as support the project management team in delivering expert assessment for project requirements and study design. Building relationships with Science Faculty groups to bring cutting edge tools, resources and analysis techniques to the P&P group will be an essential part of the role. Department Operations Group Details The Genome Analysis Centre is an institute supported by the BBSRC to ensure that biological science in the UK has access to a skill base in genomics technologies and bioinformatics to deliver programmes leading to improved food security, advances in industrial biotechnology and improved human health and wellbeing. The Institute is located on the Norwich Research Park (NRP), together with The Sainsbury Laboratory, the John Innes Centre, and the Institute of Food Research, the University of East Anglia and the Norfolk and Norwich University Hospital. The research park has an excellent reputation for research in plant and microbial sciences, interdisciplinary environmental science and food, diet and health. The NRP recently received £26M government investment for innovation and infrastructure to attract science and technology companies to establish a vibrant environment to realise economic impact from research investment. Capability in DNA sequencing and the integrated use of multiple sequencing technologies to further our fundamental understanding of genomes, and how they function, will be at the heart of our scientific programmes and the work that we undertake in collaboration with other research institutes, universities and industry throughout the UK, and internationally. TGAC actively explores and implements new applications of DNA sequencing technologies and has automated many of the routine laboratory steps to accelerate and ensure high reproducibility of sequence data. The work on data generation will complement TGAC’s growing strengths in bioinformatics analysis and interpretation of multiple, complex data sets and in developing novel platforms to provide access to computational tools and processing capacity for a variety of users. TGAC is a UK hub for innovative bioinformatics and genomics and their applications in a broad spectrum of bioscience. Our mission is to provide a flexible approach to the generation of data from biological systems Advert Text The Genome Analysis Centre (TGAC) has an exciting new role for a Bioinformatics Manager in the Platforms and Pipelines (P&P) group. The successful candidate will lead the P&P Bioinformatics team to drive high-quality data analysis for the BBSRC National Capability in Genomics (NCG), which provides access to state of the art genomics technologies for research groups throughout the UK. This role will oversee two key functions: the strategic development of a broad portfolio of bioinformatics data analyses to be delivered via the P&P Team, as well as delivering high quality primary data analysis and expert bioinformatics support to internal and external customers. The successful candidate will be expected to have a deep understanding of, and interest in, a wide variety of analysis including genome assembly, targeted re-sequencing, genotyping, transcriptomics, epigenetics and metagenomics in a range of non-model and model systems. TGAC is a vibrant, contemporary research institute and a UK hub for innovative Bioinformatics through research, analysis and interpretation of data sets. We hosts one of the largest computing hardware facilities dedicated to life science research in Europe and our aim is to ensure that biological science in the UK has access to a skill base in genomics and bioinformatics to deliver programmes leading to improved food security, advances in industrial biotechnology and improved human health and wellbeing. At TGAC we offer competitive salaries, excellent defined contribution pension scheme, life assurance, tailored learning and development and onsite sports facilities that are available to all staff and their guests. As a user of the disability symbol, we guarantee to interview all disabled applicants who meet the minimum essential criteria for this vacancy. Key relationships Internal: Reporting to the Head of Platforms and Pipelines (P&P), with close liaison with other P&P managers (Project Management and Operations), the Head of Scientific Computing (SC) and Business Development and Communications (BD&C) Groups within the Operations Divisions, as well as all of the Science Faculty. Managing: A team of 3 Bioinformaticians, with additional posts to be recruited. Interacting with: All TGAC staff, and wider collaborators. External: National Capability in Genomics customers and collaborators, industry partners and bioinformatics service and software companies, nationally and internationally. There will also be some interactions with partners on the Norwich Research Park and our shared corporate service provider (NBIP). Main Activities & Responsibilities Facilitating knowledge transfer from TGAC’s Science Faculty so that cutting edge tools and analysis techniques can be deployed as a service. Delivering expert advice on study design to ensure that projects have sufficient power for downstream analysis Providing specialist bioinformatics advice and assistance to stakeholders in troubleshooting bioinformatics analyses. Maintaining excellent current awareness of new analysis protocols and opportunities that can strengthen the P&P bioinformatics portfolio. Developing and extending automation for efficient QC monitoring and primary data processing from a diverse range of platforms (Currently Illumina HiSeq/MiSeq, PacBio, Ion Proton, Oxford Nanopore MinION, Opgen Argus, BioNanoGenomics Irys, but will expand in the future as new technology arises). Overseeing timely, accurate and high-quality completion of projects in collaboration with the P&P Project Management team. Maintain clear communications with those performing library construction and Sequencing to drive process improvement through QC monitoring. Gathering requirements for TGAC’s Software Development team to drive development of laboratory process support systems (MISO LIMS/Atlassian JIRA). Overseeing and performing analysis of genomic data. Cross-training team members to provide essential business continuity. Education & Qualifications Requirement Importance University degree in a relevant discipline (e.g. Computer Science, Software Engineer, bioinformatics). Essential PhD in a relevant discipline, e.g. Computer Science, Software Engineer, Bioinformatics, Biological sciences). Desirable Specialist Knowledge & Skills Requirement Importance Management skills – demonstrated through the management of a team or project. Essential Broad and deep knowledge of computational methods for high-throughput sequence analysis and interpretation. Essential Track record in the development of bioinformatics tools applied to analysis of genomics data. Desirable Demonstrable knowledge of programming languages and database management systems and SQL with a focus on the analysis of large datasets. Desirable Relevant Experience Requirement Importance Extensive experience in delivering bioinformatics as a service. Essential Experience of working in a production customer-focused environment. Essential Experienced manager (management of change, funding and financial sustainability). Essential Experience of working in a high throughput genomics environment with disciplined delivery of high quality data and analysis. Desirable Experience of working with HPC job submission. Desirable Interpersonal & Communication Skills Requirement Importance Demonstrable development of own skills and skills of others. Essential Demonstrable use of innovative approaches and continuous improvement. Essential Able to value others contributions and give others dignity and respect. Essential Good oral and written communications skills. Essential Able to lead and motivate an effective team, and a good team player. Essential Able to demonstrate confidentially in working with a range of customers and collaborators, including industrial partners. Essential Good problem solver, able to logically identify solutions to technical problems. Essential Able to see the bigger picture and contribute towards strategy discussions. Essential
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]