Job Area: Computational Biology
MD Anderson is known for providing cancer patients with exceptional care, which includes early access to innovative new treatments through clinical trials. The Institute for Applied Cancer Science (IACS) is a new hybrid model that uniquely combines the drug discovery capabilities of the biopharmaceutical industry and the extensive knowledge of biology found in academia with the expertise of MD Anderson's top clinicians. IACS has the singular goal of rapidly developing novel, effective and safe therapeutics that improve patient health. IACS executes programs with the highest probability of clinical success in a rigorous, goal-oriented, data-driven manner. [More]
We are seeking a Postdoctoral Scientist in Inflammation to join Professor Alison Simmons’ research group. The goal of this project is to characterise pathogenic lesions in Crohn’s disease at a global molecular level to highlight biological pathways that are over or underactive within human intestinal subsets in Crohn’s. The Postdoctoral Fellowship is being funded and performed in close collaboration with Celgene, and will involve short secondments within Celgene labs to for the postholder to develop skills linked to work in industry. In Oxford the Postdoctoral Scientist will work in collaboration with members of the Target Discovery Institute and Wellcome Trust Centre for Human Genetics, Oxford. [More]
We are seeking two Postdoctoral Scientists to join Professor Chris Newbold’s Molecular Parasitology research group to work on the understanding of immunity and pathogenesis in malaria. The role will involve work on the control of expression of these multi-gene families, their function and the immune response to them using extensive sequence data that has been compiled. [More]
A postdoc position funded by an ERC Consolidator grant is available in theVan Attikum laboratory at the Leiden University Medical Center (LUMC; Leiden, the Netherlands). As a postdoc you will study how chromatin remodeling enzymes counteract DNA strand breaks and replication stress in order to prevent genomic instability in human cells. The research will encompass a cross-disciplinary approach that combines novel and cutting-edge genomics with bioinformatics, genetics, biochemistry and high-resolution microscopy. [More]
We are looking for a dynamic leader in computational biology to join EMBL-EBI as Head of Research. EMBL-EBI is one of the world’s leading bioinformatics institutes with around 600 staff with a focus on both computational biology research and bioinformatics service delivery. Research at EMBL-EBI comprises 8-10 dedicated research groups along with 4 further teams who combine research activities and service delivery. As Head of Research you will provide leadership for the entire EBI research portfolio – similar to a Head of Department in a University setting but without teaching and with minimal administration commitments. You will also run your own research group. This is an exciting opportunity for a successful scientist with high calibre leadership skills to provide strategic direction for EMBL-EBI’s research and have substantial influence in the broader European computational biology research area. [More]
The Senior Bioinformatics Engineers an exceptional candidate who has both deep bioinformatics experience and extensive software architecture experience. We operate at the crossroads of cancer genomics, software, and data science and are looking for that rare individual who has experience and passion for all three. Our platforms are focused on mining of cancer genomic data sets, understanding resistance to targeted therapy, matching genomic profiles to clinical trials, and identifying exceptional responders to targeted therapy. Technical and scientific challenges for the platform include data mining and visualization of large-scale cancer genomic data sets, extracting information from natural language text and building web-based data analytics platforms. [More]
The division 'Proteomics of Stem Cells and Cancer' is looking for a postdoc to strengthen its research in the area of cancer proteomics. Our division (headed by Prof. Jeroen Krijgsveld) is funded by the Excellence Cluster CellNetworks and is part both of the DKFZ and the Medical Faculty of Heidelberg University. We are housed in a fully newly equipped laboratory including state-of-the-art mass spectrometry (e.g. Orbitrap QE-HF and Fusion), and we collaborate with many groups on campus, in Heidelberg, and internationally. Our main research interest is to develop proteomic tools that help us to understand how the proteome is dynamically regulated in time and space, and how this underlies properties related to malignancy in cancer and to pluripotency in stem cells. Our current research focuses on the role of secretory proteins, protein interactions in chromatin, and proteins that interact with RNA. The postdoc position is available to work in the area of quantitative cancer proteomics, focusing on protein expression profiling and integration with NGS, or its intersection with chromatin biology and signal transduction, depending on the interest and expertise of the candidate. [More]
Moderna is seeking an exceptionally talented and highly motivated research scientist with experience in next-generation sequencing (NGS) technologies to lead a highly collaborative, multi-disciplinary, and fast-paced team within the Platform Analytics group. The primary focus for this position is to leverage NGS platforms to analyze a broad range of RNA and DNA samples using various methods. The successful candidate will work with multiple groups across the company to develop and implement state-of-the-art methods using NGS technology. [More]
Cellular differentiation refers to acquisition of specific cell-fates during development. It has become evident that this process involves genomewide reprogramming of epigenetic modifications such as histone marks resulting in transcriptional changes that drives cell-fate. Building on our expertise in epigenomics and gene regulation, we aim to investigate function of certain novel chromatin regulators and transcription factors in mediating epigenome and transcriptome reprogramming during lineage commitment and terminal differentiation. [More]
As part of our continued investment in the School of Biological Sciences (BIO) at UEA, we seek to recruit 4 talented, ambitious and dynamic lecturers. These appointments will add to thriving research areas withinBIO, and foster interdisciplinary collaborative work across the Faculty of Science, the Faculty of Health and our partner institutes on the Norwich Research Park. Successful candidates will be expected to develop an internationally competitive research programme that complements existing research strengths within the School. The specific research areas for this particular post include regulatory small RNAs, developmental biology and evolution. We particularly welcome applications from investigators with experience in analysing next-generation sequencing data (transcriptome, genome or epigenome sequencing). [More]