Job Company: Imperial College London
Applications are invited for a Research Associate position to join the Structural Bioinformatics Group, within the Department of Life Sciences based at the South Kensington Campus. The post is part of a joint UK (funded by the BBSRC) and USA (funded by the NSF) grant. Our colleagues in the USA are the group of Prof Vakser (university of Kansas) who will be using our predicted structures as the basis to predict structures for protein complexes. [More]
The Centre’s Early Career Fellowship Programme provides a unique opportunity for early-career scientists working in the broad area of environment and health to develop their own competitive, independent research programmes in a supportive, multi-disciplinary environment. The fellowship programme is designed as a platform to apply for subsequent intermediate fellowships and similar career progressing schemes. [More]
The post-holder will take a leading role in developing a statistical framework to link surveillance data with other data sources and produce spatially explicit estimates of risk of outbreak spread. The statistical framework will then be tested and validated against historical data. The workflow will be implemented in an open-source, modular package which in the long run will be used for real-time analyses to inform stake-holders and policy makers. [More]
Applications are invited for a Bioinformatics Software Developer to join the Structural Bioinformatics Group, at the South Kensington Campus. Working as a member of a small team developing the software for the PhyreRisk portal you will provide a dynamic web portal to deliver to the community a resource relating human genetic variation, disease, protein structure and biological pathways. [More]
Applications are invited for a skilled and motivated Bioinformatics Programmer to join the Imperial BRC Genomics Facility on the Hammersmith Campus of Imperial College London. You will implement, maintain and operate data management and processing pipelines for next-generation sequencing data generated by the facility. You will work closely with other bioinformaticians in the facility and with staff at the Imperial High Performance Computing Service and Data Centre. [More]
Imperial College London Imperial BRC Genomics Facility Division of Diabetes, Endocrinology and Metabolism Department of Medicine Head of Imperial BRC Genomics Facility Salary range: £43,980 – £53,160, per annum Full-time, fixed-term until 31 March 2017 in the first instance Hammersmith Campus Applications are invited for a skilled and motivated scientist to head the NIHR Imperial BRC Genomics Facility on the Hammersmith Campus of Imperial College. The Facility provides state-of-the-art laboratory and computational support for translational research that harnesses genome information to advance disease diagnostics, prognosis and treatment. The facility provides access to the latest next-generation sequencing (NGS) platforms including the Illumina HiSeq 2500 and Illumina MiSeq. It is responsible for the management and processing of NGS data and carries out bioinformatics analysis of large-scale genomic data sets. It develops and maintains computational pipelines for NGS data processing and analysis utilising cutting edge bioinformatics tools and high-performance computing resources. The Head of Imperial BRC Genomics Facility will be responsible for managing the Imperial BRC Genomics Facility which offers integrated laboratory and informatics support for translational next-generation sequencing projects to clinicians and scientist across Imperial College. The post holder will coordinate the laboratory, genome sequencing and data analysis services including the required IT and data management infrastructure. He/she will oversee the implementation of SOPs, processes and policies that will ensure the smooth running of the facility and the delivery of state of the art support for genomics research projects. He/she will ensure that adequate analysis pipelines for large-scale genomic data are in place and oversee the bioinformatics support offered by the Facility. The post holder will provide expert advice on the design and implementation of translational genomics projects to investigators, raise awareness of new genome technologies and play a key role in strategic decision making regarding genomics support across the Faculty and College. He/she will oversee the administration and finances of the Facility and is expected to identify sources of grant funding and work with the academic team to secure grants in related areas of research. The post holder will develop their own research themes within the remit of genomics and publish novel research findings in peer reviewed journals appropriate to the area of research. The post holder will be expected to provide coordinated training of investigators who work with genomics data. Additionally, the appointee will contribute to Masters programmes, support PhD supervision, engage with short course development and delivery, and to appropriate undergraduate programmes. The College cannot normally apply for a Certificate of Sponsorship for this post under Tier 2 of the UK Border Agency’s Points Based System. Any candidate, who is considering applying for this position and requires sponsorship, must ensure that they are able to obtain permission to work in the UK through an appropriate immigration route. [More]
Imperial BRC Genomics Facility Investigative Medicine Section Division of Diabetes, Endocrinology and Metabolism Department of Medicine LEAD BIOINFORMATICIAN Salary range: £43,980- £53,160 per annum Full-time, fixed-term until 31 March 2017 Hammersmith Campus Applications are invited for a skilled and motivated Lead Bioinformatician to join the NIHR Imperial BRC Genomics Facility on the Hammersmith Campus. The Facility provides state-of-the-art laboratory and computational support for translational research that harnesses genome information to advance disease diagnostics, prognosis and treatment. The Facility provides access to the latest next-generation sequencing (NGS) platforms including the Illumina HiSeq and MiSeq. It is responsible for the management and processing of NGS data and carries out bioinformatics analysis of large-scale genomic data sets. It develops and maintains computational workflows for NGS data processing and analysis utilising cutting edge bioinformatics tools and high-performance computing resources. The post is funded by the Imperial Biomedical Research Centre (BRC) to support the investigation of the genetic basis of common and rare human diseases using state-of-the-art genome technologies. The successful applicant will lead the bioinformatics support within the Facility and work with clinicians and scientists from groups across the Faculty of Medicine and the BRC Genomics Facility to analyse large-scale genomic datasets predominantly obtained by NGS based approaches such as whole-genome and exome re-sequencing, RNA-seq and ChIP-seq. The post holder will carry out the analysis of next-generation sequencing data and supervise the work of junior bioinformaticians in the Facility. Activities will include quality control and mapping of NGS data for variant detection, transcription profiling or epigenetic modification detection; integration of genomic datasets with public and commercial biomedical data sources for annotation and interpretation; development, maintenance and optimisation of analysis pipelines and procedures. The ability to make strategic contributions to experimental design and assist clinicians and scientists with data interpretation are key requirements of the post. The ideal candidate will have a degree in a biomedical science and an equivalent qualification and proven track record in bioinformatics or a closely related discipline. Applicants must have a sound understanding of the application of genome technologies and bioinformatics in the context of genomics and genetics and practical experience with the processing and analysis of large genomic, preferably next-generation sequencing datasets. The ability to communicate effectively in a multi-disciplinary research environment is essential. Experience of staff supervision will be advantageous. Informal enquiries are welcome and can be made to Professor Jorge Ferrer (tel: +44 (0)20 759 40968, email: jorge.ferrer@imperial.ac.uk). For more information on the Imperial BRC Genomics Facility please visit http://www.imperial.ac.uk/genomicsfacility. The College cannot normally apply for a Certificate of Sponsorship for this post under Tier 2 of the UK Border Agency’s Points Based System. Any candidate, who is considering applying for this position and requires sponsorship, must ensure that they are able to obtain permission to work in the UK through an appropriate immigration route. Our preferred method of application is online via our website via the Apply through website button (please select “Job Search” then enter the job title or vacancy reference number into “Keywords”). Please complete and upload an application form as directed quoting reference number HM2016037. Alternatively, if you are unable to apply online, please email m.badiani@imperial.ac.uk to request an application form. Closing date: 10 March 2016 (Midnight GMT). Imperial Managers lead by example. Committed to equality and valuing diversity. We are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Two Ticks Employer and are working in partnership with GIRES to promote respect for trans people. [More]
Faculty of Medicine School of Public Health Department of Epidemiology and Biostatistics MED BIO Fellow in Molecular Epidemiology / Biostatistics Salary range: £33,860 to £42,830 p.a. MED-BIO is a recent major MRC funded medical informatics initiative led by Imperial College London. The aim of this programme is to bring together patient/cohort data, new omics technologies, computing and other resources, with dedicated infrastructure in data management, integration, analysis and visualisation, to enable major advances in understanding the aetiopathogenesis of chronic human diseases, and the gene-environment-microbiome interactions that underpin them. As part of the MED-BIO programme, we are seeking to appoint a talented fellow in molecular epidemiology / biostatistics to support this ambitious programme of work. Appointments will be based on research excellence and track records, equally though we will look to appoint individuals with a background in epidemiology, statistics, bioinformatics or a related quantitative discipline, who wish to apply their expertise to understanding the aetiology, pathogenesis, pathways and mechanisms of chronic human disease. The appointee will have the opportunity to spend up to 1 year in a second research centre or UK industrial centre. Successful candidates are expected to develop their own competitive independent research programmes, submit to major funders a coherent competitive proposal, and to support their research programme and the next stage of their career development in either a senior fellowship or substantive post. A rigorous and thorough selection procedure akin to MRC Strategic Skills - Biomedical Informatics Fellowship scheme will be adopted. Applicants should hold a PhD or equivalent in epidemiology, bioinformatics, biostatistics, statistical genomics, machine learning or related quantitative disciplines The post is full time for a fixed term of 60 months. The fellowship programme will be based at Imperial College London. [More]
The Institute for Translational Medicine and Therapeutics (ITMAT) within the NIHR Imperial Biomedical Research Centre (BRC) supports the acceleration of fundamental discoveries into improvements in human health and economic benefit. ITMAT includes platforms in genomic sequencing, metabolic phenotyping, bioresources, imaging technologies and health informatics [More]
Imperial College London - Department of Infectious Disease EpidemiologySalary: Not specified [More]