Job Company: Ragon Institute of MGH, MIT and Harvard

One position is open for full time bioinformatics specialist in Yu’s group at Ragon Institute of MGH, MIT and Harvard. The candidate will assist in research on high-throughput data analysis, including but not limited to Microarray, RNAseq, Flow Cytometry and Protein Omics, for pathogenesis and viral persistent during HIV-1 infection. Knowledge gained from these analyses will support biologists to guide the design of more effective vaccines and treatments against various infectious pathogens including HIV and Influenza. [More]

Job Title:        Postdoctoral Fellow to study viral evolution and broadly neutralizing antibody responses in HIV infection  Salary Plan:   NIH and institutional funding Lab:    Allen               Direct Supervisor: Todd Allen Employing Hospital and Department:        Ragon Institute of MGH, MIT, and Harvard Minimum degree and field of knowledge: PhD, MD Years experience required:  0 – 2 years experience Summary: The Ragon Institute of MGH, MIT and Harvard located in Kendall Square in Cambridge, MA has an opening in the Allen laboratory (http://www.ragoninstitute.org/portfolio-item/allen-lab/) for a highly motivated postdoctoral fellow to study the role of HIV sequence evolution in the development of broadly neutralizing antibodies. This position requires a Ph.D. or an M.D. with a background in humoral immunity, evolutionary biology, and/or bioinformatics. Research will focus on elucidating the role that viral evolution and escape from humoral immune responses plays in the development and maturation of broadly neutralizing antibodies to HIV. Efforts will include application of next generation sequencing (NGS) technologies to address these questions and development of advanced comparative genomic tools for the analysis of large viral genomic NGS datasets. Goals are to understand the role of HIV sequence evolution in the development of broadly neutralizing antibodies and apply this knowledge to design the effective components of an HIV vaccine. State-of-the-art facilities are available within an exceptionally energetic research setting. Job Duties: Under the direction of the principal investigator the applicant independently carries out daily activities of the laboratory. Performs molecular biology and cell-based assays utilizing standard techniques (DNA/RNA extraction and analysis, standard and quantitative PCR, site-directed mutagenesis, neutralization assays, ELISAs) Next-generation Illumina library construction and sequencing Bioinformatic analysis of conventional bulk and next-generation sequence data Develop advanced comparative genomic tools for the analysis of large viral genomic NGS datasets Detailed documentation of the experimental work  [More]

The candidate should be highly trained and have substantial experience in genomics, bioinformatics, computational biology, human population genetics,... From Indeed - 15 Jan 2016 19:11:42 GMT - View all Cambridge jobs [More]