Job Requirements: M.Sc. or higher Degree in Bioinformatics
Imperial College London Imperial BRC Genomics Facility Division of Diabetes, Endocrinology and Metabolism Department of Medicine Head of Imperial BRC Genomics Facility Salary range: £43,980 – £53,160, per annum Full-time, fixed-term until 31 March 2017 in the first instance Hammersmith Campus Applications are invited for a skilled and motivated scientist to head the NIHR Imperial BRC Genomics Facility on the Hammersmith Campus of Imperial College. The Facility provides state-of-the-art laboratory and computational support for translational research that harnesses genome information to advance disease diagnostics, prognosis and treatment. The facility provides access to the latest next-generation sequencing (NGS) platforms including the Illumina HiSeq 2500 and Illumina MiSeq. It is responsible for the management and processing of NGS data and carries out bioinformatics analysis of large-scale genomic data sets. It develops and maintains computational pipelines for NGS data processing and analysis utilising cutting edge bioinformatics tools and high-performance computing resources. The Head of Imperial BRC Genomics Facility will be responsible for managing the Imperial BRC Genomics Facility which offers integrated laboratory and informatics support for translational next-generation sequencing projects to clinicians and scientist across Imperial College. The post holder will coordinate the laboratory, genome sequencing and data analysis services including the required IT and data management infrastructure. He/she will oversee the implementation of SOPs, processes and policies that will ensure the smooth running of the facility and the delivery of state of the art support for genomics research projects. He/she will ensure that adequate analysis pipelines for large-scale genomic data are in place and oversee the bioinformatics support offered by the Facility. The post holder will provide expert advice on the design and implementation of translational genomics projects to investigators, raise awareness of new genome technologies and play a key role in strategic decision making regarding genomics support across the Faculty and College. He/she will oversee the administration and finances of the Facility and is expected to identify sources of grant funding and work with the academic team to secure grants in related areas of research. The post holder will develop their own research themes within the remit of genomics and publish novel research findings in peer reviewed journals appropriate to the area of research. The post holder will be expected to provide coordinated training of investigators who work with genomics data. Additionally, the appointee will contribute to Masters programmes, support PhD supervision, engage with short course development and delivery, and to appropriate undergraduate programmes. The College cannot normally apply for a Certificate of Sponsorship for this post under Tier 2 of the UK Border Agency’s Points Based System. Any candidate, who is considering applying for this position and requires sponsorship, must ensure that they are able to obtain permission to work in the UK through an appropriate immigration route. [More]
Location: Heidelberg, Germany Staff Category: Staff Member Contract Duration: 3 years Grading: 4, 5 or 6, depending on experience and qualifications Closing Date: 10 April 2016 Reference Number: HD_00832 Job Description The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy). EMBL is seeking a highly motivated bioinformatics engineer to work in the group of Prof. Matthias Hentze. The research focuses on the discovery of novel RNA-binding proteins and identifying their role in health and disease. The group uses new next-generation sequencing and mass-spectrometry-based technologies to identify and functionally characterize RNA-binding protein targets. The successful applicant will be involved in the computational analysis and interpretation of these data. She/he will create workflows based on existing tools and further develop analysis methodologies in order to translate novel data types into biological discoveries. The successful candidate will be the bioinformatics keystone of a research team, collaborating closely with experimentalists that produce large amounts of data. This position is tightly embedded in the overall research of the lab and will make crucial contributions to the scientific outcomes. The position provides a unique opportunity to acquire practical data science skills that are in high demand and to develop a career in cutting edge bioinformatics services and infrastructures. The position will be supported by a senior bioinformatics postdoc in the lab and will be complemented by an excellent network of bioinformaticians as well as computational and scientific facilities at EMBL. [More]
Two postdoctoral positions are available at the new Clinical Bioinformatics lab at Imagine Institute for Genetic diseases, headed by Dr. Antonio Rausell. Job description Imagine is an interdisciplinary research center focused on human genetic diseases located at the Necker Hospital campus in the heart of Paris. Imagine is affiliated with the Université Paris Descartes (Sorbonne Paris Cité), the INSERM French National Institute for Medical Research and the Paris Public Hospitals Group (Assistance Publique-Hôpitaux de Paris). Imagine has recently launched a new research Laboratory in Clinical Bioinformatics under the direction of Dr. Antonio Rausell. The laboratory develops statistical methods and bioinformatics pipelines with a clinical focus on the following two main research lines: 1) Computational assessment and prioritization of human rare genetic variants with a potential clinical impact and application to disease-specific sequencing projects. Both coding and non-coding variants will be considered. The work will integrate large-scale genome/exome sequencing, transcriptomes (RNA-seq), high-throughput proteomics (mass spectrometry), immune phenotyping and clinical datasets both from public and in-house sources. Development of predictive tools will include machine-learning techniques such as Bayesian classifiers and SVMs. The goal is implementing software to help decision-making at the clinic. 2) Statistical analyses of high-dimensional single-cell data of human cells (mainly single-cell RNA-seq) with a focus on immune disorders and susceptibility to infectious diseases. Computational methods will be developed to cope with different noise sources and complex experimental designs: e.g. multiple conditions/stimuli and time points, simultaneous analyses of host and intracellular pathogens and several read-outs from the same cells, e.g.: genome and transcriptome, transcriptome and proteome, etc. The goal is the identification of cell markers with clinical value for diagnosis and treatment. In this context, the Clinical Bioinformatics lab is hiring two postdocs with complementary expertise in order to i) take the lead in one of the two previous research lines, ii) being able to assist the other line with specific skills if needed, and iii) set up the suite of common data and pipelines to build the core’s lab. As someone said before: “we hire smart people so they can tell us what to do”. [More]
Imperial BRC Genomics Facility Investigative Medicine Section Division of Diabetes, Endocrinology and Metabolism Department of Medicine LEAD BIOINFORMATICIAN Salary range: £43,980- £53,160 per annum Full-time, fixed-term until 31 March 2017 Hammersmith Campus Applications are invited for a skilled and motivated Lead Bioinformatician to join the NIHR Imperial BRC Genomics Facility on the Hammersmith Campus. The Facility provides state-of-the-art laboratory and computational support for translational research that harnesses genome information to advance disease diagnostics, prognosis and treatment. The Facility provides access to the latest next-generation sequencing (NGS) platforms including the Illumina HiSeq and MiSeq. It is responsible for the management and processing of NGS data and carries out bioinformatics analysis of large-scale genomic data sets. It develops and maintains computational workflows for NGS data processing and analysis utilising cutting edge bioinformatics tools and high-performance computing resources. The post is funded by the Imperial Biomedical Research Centre (BRC) to support the investigation of the genetic basis of common and rare human diseases using state-of-the-art genome technologies. The successful applicant will lead the bioinformatics support within the Facility and work with clinicians and scientists from groups across the Faculty of Medicine and the BRC Genomics Facility to analyse large-scale genomic datasets predominantly obtained by NGS based approaches such as whole-genome and exome re-sequencing, RNA-seq and ChIP-seq. The post holder will carry out the analysis of next-generation sequencing data and supervise the work of junior bioinformaticians in the Facility. Activities will include quality control and mapping of NGS data for variant detection, transcription profiling or epigenetic modification detection; integration of genomic datasets with public and commercial biomedical data sources for annotation and interpretation; development, maintenance and optimisation of analysis pipelines and procedures. The ability to make strategic contributions to experimental design and assist clinicians and scientists with data interpretation are key requirements of the post. The ideal candidate will have a degree in a biomedical science and an equivalent qualification and proven track record in bioinformatics or a closely related discipline. Applicants must have a sound understanding of the application of genome technologies and bioinformatics in the context of genomics and genetics and practical experience with the processing and analysis of large genomic, preferably next-generation sequencing datasets. The ability to communicate effectively in a multi-disciplinary research environment is essential. Experience of staff supervision will be advantageous. Informal enquiries are welcome and can be made to Professor Jorge Ferrer (tel: +44 (0)20 759 40968, email: jorge.ferrer@imperial.ac.uk). For more information on the Imperial BRC Genomics Facility please visit http://www.imperial.ac.uk/genomicsfacility. The College cannot normally apply for a Certificate of Sponsorship for this post under Tier 2 of the UK Border Agency’s Points Based System. Any candidate, who is considering applying for this position and requires sponsorship, must ensure that they are able to obtain permission to work in the UK through an appropriate immigration route. Our preferred method of application is online via our website via the Apply through website button (please select “Job Search” then enter the job title or vacancy reference number into “Keywords”). Please complete and upload an application form as directed quoting reference number HM2016037. Alternatively, if you are unable to apply online, please email m.badiani@imperial.ac.uk to request an application form. Closing date: 10 March 2016 (Midnight GMT). Imperial Managers lead by example. Committed to equality and valuing diversity. We are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Two Ticks Employer and are working in partnership with GIRES to promote respect for trans people. [More]
Faculty of Medicine School of Public Health Department of Epidemiology and Biostatistics MED BIO Fellow in Molecular Epidemiology / Biostatistics Salary range: £33,860 to £42,830 p.a. MED-BIO is a recent major MRC funded medical informatics initiative led by Imperial College London. The aim of this programme is to bring together patient/cohort data, new omics technologies, computing and other resources, with dedicated infrastructure in data management, integration, analysis and visualisation, to enable major advances in understanding the aetiopathogenesis of chronic human diseases, and the gene-environment-microbiome interactions that underpin them. As part of the MED-BIO programme, we are seeking to appoint a talented fellow in molecular epidemiology / biostatistics to support this ambitious programme of work. Appointments will be based on research excellence and track records, equally though we will look to appoint individuals with a background in epidemiology, statistics, bioinformatics or a related quantitative discipline, who wish to apply their expertise to understanding the aetiology, pathogenesis, pathways and mechanisms of chronic human disease. The appointee will have the opportunity to spend up to 1 year in a second research centre or UK industrial centre. Successful candidates are expected to develop their own competitive independent research programmes, submit to major funders a coherent competitive proposal, and to support their research programme and the next stage of their career development in either a senior fellowship or substantive post. A rigorous and thorough selection procedure akin to MRC Strategic Skills - Biomedical Informatics Fellowship scheme will be adopted. Applicants should hold a PhD or equivalent in epidemiology, bioinformatics, biostatistics, statistical genomics, machine learning or related quantitative disciplines The post is full time for a fixed term of 60 months. The fellowship programme will be based at Imperial College London. [More]
TBD + benefits: University of NC Chapel Hill, A. Sancar Lab: Postdoc positions are available in the laboratory of Aziz Sancar at the University of North Carolina at Chapel Hill to study whole genome analysis of DNA damage and nucleotide excision repair. Chapel Hill, North Carolina (US) [More]
DOE Salary ranges from $44,900 to $54,100 per annum plus benefits (this is shown in the ad): National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK), National Institutes of Health (NIH): We are utilizing genomic tools (whole genome sequence data, methylation data, large-scale association analyses) to identify and characterize novel genes that cause type 2 diabetes and obesity in human populations. Phoenix, Arizona [More]
Salary is based on candidate experience: Trustees of Boston College: Two NIH funded postdoctoral positions in microbial systems biology and antibiotic resistance are available in the van Opijnen lab at the Biology Department at Boston College. Boston, Massachusetts (US) [More]
The Genome, Environment and Microbiome (GEM) Community of Excellence (www.buffalo.edu/gem) at the University at Buffalo (UB) is seeking a highly motivated postdoctoral-level bioinformatics research scientist with a background in microbiome analysis. [More]
Commensurate with Experience: TTU Center for Biotechnology and Genomics: The Center for Biotechnology and Genomics (CBG), a multidisciplinary center at Texas Tech University (TTU), seeks a non-tenure-track faculty member with expertise in bioinformatics to join dynamic interdisciplinary programs at TTU Lubbock, Texas [More]