Job Requirements: M.Sc. or higher Degree in Bioinformatics
Saint Louis University, a Catholic, Jesuit institution dedicated to student learning, research, health care, and service is seeking applicants for a tenure-track Assistant Professor position in the Department of Biology. All applications must be made online via the Apply through website button (req #F20150192) and should include a cover letter, curriculum vitae, a research statement, and a statement of teaching experience and philosophy. In addition, please have three letters of reference sent by mail to Dr. Robert Wood, Department of Biology, Saint Louis University, 3507 Laclede Avenue, St. Louis, MO, 63103-2010 or by email to watkinst@slu.edu. Applications received by December 15, 2015 are assured full consideration and the search will continue until suitable candidates are identified. Additional information on the BCB program or Department of Biology can be found at http://bioinformatics.slu.edu and http://bio.slu.edu. [More]
The Vrije Universiteit Brussel (VUB), in collaboration with the Universiteit Gent (UG), is seeking candidates for a postdoctoral position in structural bioinformatics. The research project will investigate how sequence-based predictions of protein characteristics can be fully exploited on a large statistical scale to better understand their experimentally observed behavior, especially in relation to folding events, protein stability and post-translational modifications. It connects structural bioinformatics (Wim Vranken at the Structural Biology Brussels (SBB), VUB), machine learning (Tom Lenaerts at the Artificial Intelligence group (AI), VUB) and proteomics (Lennart Martens at the Computational Omics and Systems Biology Group, UG). The successful candidate will be mainly located at the (IB)2 Interuniversity Institute of Bioinformatics in Brussels (http://ibsquare.be), an institute that brings together the science, engineering and medical faculties of VUB and the Université Libre de Bruxelles (ULB) in a collaborative and open atmosphere. The focus of the (IB)2 is on interdisciplinary research, with expertise in machine learning, big data, rare diseases, oligenic disorders, network analysis, genome analysis, metagenomics and structural bioinformatics. Research context: The interactions and function of proteins are determined by their dynamics and conformations. Proteins can adopt context-dependent and interchanging conformations, as illustrated by allosteric changes induced by binding events or by post-translational modifications. Local sequence-based interactions between amino acids have a large influence on these preferential conformations, even when long-range stabilizing interactions are present. In this project, we investigate the influence of such local interactions on the behavior of proteins, from folded to intrinsically disordered. These analyses are possible through novel and unique tools and databases developed by our groups, such as DynaMine (http://dynamine.ibsquare.be), Start2Fold (http://start2fold.eu) and PepShell (http://compomics.github.io/projects/pepshell.html). The successful candidate will gather further relevant experimental data from public databases and literature and connect these data to results from sequence- and structure-based predictions in order to construct innovative computational approaches that can guide new experimental work in protein folding, stability and post-translational modifications. Offer: A full time postdoctoral position for the duration of 3 years funded by the Research Foundation – Flanders (FWO), pending a review after the first 6 months. [More]
The Helmholtz Zentrum München in Munich, Germany, is member of one of the leading research associations in Europe - the Helmholtz Association of German Research Centers. The aim of our research is to proactively detect health risks involving humans and the environment, decoding the mechanisms of pathogenesis and developing concepts for prevention and therapy. Idiopathic pulmonary fibrosis is characterized by altered cell composition and homeostasis leading to loss of function (Fernandez et al, Lancet 2012;380:680-88). To find anti-fibrotic strategies understanding cellular processes of disease development is crucial. Recently, we started this by identifying dynamics of biological processes and networks on the proteomic level (Schiller et al, Molecular Systems Biology 2015;11:819). Based on our recent works on the analysis of single cell transcriptomics to correct for latent confounders such as cell cycle (Buettner et al, Nature Biotechnology 2015;33:155-160) and to visualize developmental processes (Haghverdi et al, Bioinformatics 2015; 31:2989-2998), we want to model and analyze the transcriptional heterogeneity linked to disease pathomechanisms and disease classification by single-cell analysis. The Institute of Computational Biology (ICB) offers in cooperation with the Institute for Lung Biology and Disease (Comprehensive Pneumology Center, CPC) a position at the earliest possible date for a PostDoc in Single-cell Bioinformatics/ Computational Biology (2015/2935) Job Description: - single-cell-analysis - quantitative description and modeling of disease-related networks - modeling and analysis of heterogeneous gene expression Our Offer: - Working in an innovative, well-equipped and scientifically stimulating surrounding - Further training opportunities - Initial short-term employment contract for two years with a standard public service salary (TV EntgO Bund EG 13) [More]
PhD scientist for our protein engineering group. Additional postdoctoral and/or industry experience is a plus. This key contributor will use Xencor’s proprietary computational protein design technologies to develop antibody-based protein therapeutics. [More]
Bioinformatics expert to join the Global Biotherapeutic Technologies organization at Pfizer. The successful candidate will join a small team of computational biochemists and software engineers located in Cambridge, Massachusetts developing and using a broad array of computational tools to support cutting edge approaches for early stage biotherapeutic discovery. [More]
Bioinformatics scientist to support Nurix’s mission of targeting E3 ubiquitin ligases in the areas of oncology and immunology. The successful candidate will have a broad bioinformatics experience base with a good working knowledge of cancer genomics and pathway biology. This individual will work closely with our drug discovery project scientists and informatics group to build Nurix’s internal bioinformatics capabilities and address project needs. [More]
Bioinformatician to join the Ensembl Genomes Team at the European Bioinformatics Institute (EMBL-EBI) located on the Wellcome Genome Campus near Cambridge in the UK. The successful applicant will work on the VectorBase project, which focuses on invertebrate species that transmit diseases to humans and animals. [More]
Working with Dr Kathryn Elmer you will make a leading contribution to a project focusing on the genomics of major evolutionary transitions working within the Evolutionary Analysis group of IBAHCM. Further details available through http://elmerlab.blogspot.co.uk; see Opportunities Informal inquiries to the PI are welcome in advance. [More]
Computational Biologist to join the team of Toby Gibson. The post holder will have a dual role both as interface with experimental researchers with bioinformatics issues and to develop bioinformatics training courses targeted at beginner and intermediate levels. [More]
Scientific Curator to work on improving gene annotation for clinical reporting in the Vertebrate Genomics team at the European Bioinformatics Institute (EMBL-EBI) located at the Wellcome Genome Campus near Cambridge in the UK. [More]