PDF Salary range: £30655 to £38428 per annum plus excellent benefits.: Wellcome Trust Sanger Institute: We are looking for a highly motivated Single Cell RNA-seq bioinformatics Postdoctoral Fellows who will develop their career by contributing to our study and joining the Brazma/Marioni/Teichmann groups. Cambridge, Cambridgeshire (GB)  [More]

Originally posted on 2015-12-04

£32,600 - £38,896 per annum Allowances: £2,323 London Living Allowance : King's College London: The postholder will develop a platform that will let researchers easily use and share genetic, clinical and lifestyle information that has already been collected, and add new information as it is produced. London (Central), London (Greater) (GB)  [More]

Originally posted on 2015-11-26

DOE: Dana-Farber Cancer Institute : 26954 Boston, Massachusetts (US)  [More]

Originally posted on 2015-10-20

DOE: University of Central Florida: We are building a new Genomics and Bioinformatics Cluster by the fall of 2017 and we seek to hire a cluster lead to start in the fall of 2016 at the level of either Associate or Full Professor. Orlando, Florida, United States, 32827  [More]

Originally posted on 2015-11-16

The Sharjah Institute for Medical Research (SIMR), a newly established biomedical research center with state of the art research facilities, is seeking to hire highly motivated and outstanding research scientists in a number of areas including experimental pathology/toxicology, bioinformatics, and immunology.   Candidates should have extensive evidence-based experience in the construction and handling of natural and genetically-modified animal models, computational and systems biology, microarray technology, sequencing and next generation sequencing, and/or gene expression profiling.   The UOS offers generous benefit packages including tax free competitive salary commensurate with candidate qualifications and experience, furnished accommodations, fully-paid house utilities, annual roundtrip tickets, children educational allowance, and family health insurance.   For more information please contact Prof. Taleb AlTel (taltal@sharjah.ac.ae), director of the Research Institute for Medical and Health Sciences (RIMHS). To submit your application, please click on the  [More]

Originally posted on 2015-12-08

Saint Louis University, a Catholic, Jesuit institution dedicated to student learning, research, health care, and service is seeking applicants for a tenure-track Assistant Professor position in the Department of Biology.   All applications must be made online via the Apply through website button (req #F20150192) and should include a cover letter, curriculum vitae, a research statement, and a statement of teaching experience and philosophy. In addition, please have three letters of reference sent by mail to Dr. Robert Wood, Department of Biology, Saint Louis University, 3507 Laclede Avenue, St. Louis, MO, 63103-2010 or by email to watkinst@slu.edu. Applications received by December 15, 2015 are assured full consideration and the search will continue until suitable candidates are identified. Additional information on the BCB program or Department of Biology can be found at http://bioinformatics.slu.edu and http://bio.slu.edu.  [More]

Originally posted on 2015-12-09

The Vrije Universiteit Brussel (VUB), in collaboration with the Universiteit Gent (UG), is seeking candidates for a postdoctoral position in structural bioinformatics. The research project will investigate how sequence-based predictions of protein characteristics can be fully exploited on a large statistical scale to better understand their experimentally observed behavior, especially in relation to folding events, protein stability and post-translational modifications. It connects structural bioinformatics (Wim Vranken at the Structural Biology Brussels (SBB), VUB), machine learning (Tom Lenaerts at the Artificial Intelligence group (AI), VUB) and proteomics (Lennart Martens at the Computational Omics and Systems Biology Group, UG). The successful candidate will be mainly located at the (IB)2 Interuniversity Institute of Bioinformatics in Brussels (http://ibsquare.be), an institute that brings together the science, engineering and medical faculties of VUB and the Université Libre de Bruxelles (ULB) in a collaborative and open atmosphere. The focus of the (IB)2 is on interdisciplinary research, with expertise in machine learning, big data, rare diseases, oligenic disorders, network analysis, genome analysis, metagenomics and structural bioinformatics. Research context: The interactions and function of proteins are determined by their dynamics and conformations. Proteins can adopt context-dependent and interchanging conformations, as illustrated by allosteric changes induced by binding events or by post-translational modifications. Local sequence-based interactions between amino acids have a large influence on these preferential conformations, even when long-range stabilizing interactions are present. In this project, we investigate the influence of such local interactions on the behavior of proteins, from folded to intrinsically disordered. These analyses are possible through novel and unique tools and databases developed by our groups, such as DynaMine (http://dynamine.ibsquare.be), Start2Fold (http://start2fold.eu) and PepShell (http://compomics.github.io/projects/pepshell.html). The successful candidate will gather further relevant experimental data from public databases and literature and connect these data to results from sequence- and structure-based predictions in order to construct innovative computational approaches that can guide new experimental work in protein folding, stability and post-translational modifications. Offer: A full time postdoctoral position for the duration of 3 years funded by the Research Foundation – Flanders (FWO), pending a review after the first 6 months.      [More]

Originally posted on 2015-12-09

The Helmholtz Zentrum München in Munich, Germany, is member of one of the leading research associations in Europe - the Helmholtz Association of German Research Centers. The aim of our research is to proactively detect health risks involving humans and the environment, decoding the mechanisms of pathogenesis and developing concepts for prevention and therapy.  Idiopathic pulmonary fibrosis is characterized by altered cell composition and homeostasis leading to loss of function (Fernandez et al, Lancet 2012;380:680-88). To find anti-fibrotic strategies understanding cellular processes of disease development is crucial. Recently, we started this by identifying dynamics of biological processes and networks on the proteomic level (Schiller et al, Molecular Systems Biology 2015;11:819). Based on our recent works on the analysis of single cell transcriptomics to correct for latent confounders such as cell cycle (Buettner et al, Nature Biotechnology 2015;33:155-160) and to visualize developmental processes (Haghverdi et al, Bioinformatics 2015; 31:2989-2998), we want to model and analyze the transcriptional heterogeneity linked to disease pathomechanisms and disease classification by single-cell analysis.  The Institute of Computational Biology (ICB) offers in cooperation with the Institute for Lung Biology and Disease (Comprehensive Pneumology Center, CPC) a position at the earliest possible date for a  PostDoc in Single-cell Bioinformatics/ Computational Biology (2015/2935)   Job Description: - single-cell-analysis - quantitative description and modeling of disease-related networks - modeling and analysis of heterogeneous gene expression Our Offer: - Working in an innovative, well-equipped and scientifically stimulating   surrounding - Further training opportunities - Initial short-term employment contract for two years with a standard public   service salary (TV EntgO Bund EG 13)  [More]

Originally posted on 2015-12-09
2015-12-09  -  Structural Biologist/Protein Engineer Xencor  -    -  

PhD scientist for our protein engineering group. Additional postdoctoral and/or industry experience is a plus. This key contributor will use Xencor’s proprietary computational protein design technologies to develop antibody-based protein therapeutics.  [More]

Originally posted on 2015-12-10

Bioinformatics expert to join the Global Biotherapeutic Technologies organization at Pfizer. The successful candidate will join a small team of computational biochemists and software engineers located in Cambridge, Massachusetts developing and using a broad array of computational tools to support cutting edge approaches for early stage biotherapeutic discovery.  [More]

Originally posted on 2015-12-08