PhD student position in single biomolecule detection

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Job date: 2014-12-11
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Company : Chalmers University of Technology 

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Role : Student 


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Job Description:

Information about the division and the research
Rapid conceptual developments and progress in nanofabrication technologies, computational electromagnetics and optical measurement methodologies have brought optics and photonics firmly into the realm of nanoscience. Nanophotonics now encompass subfields of extremely high current interest – plasmonics, optical nanoscopy, metamaterials, to name a few. The methods and concepts developed in nanophotonics have a very broad applicability and may provide solutions to challenges as diverse as single molecule medical diagnostics, quantum optics for tomorrow’s telecom networks and environmentally friendly fuels from solar energy harvesting. The Bionanophotonics group at Chalmers is engaged in fundamental and applied nanophotonics studies at the international research frontier. The group is truly international (currently 10 nationalities represented) and consists of MSc and PhD students, post docs and senior scientists. We do experiments, theory and computer simulations and we are hevy users of Chalmers nanofabrication facility.

Because of a phenomenon called localized surface plasmon resonance (LSPR), metal nanoparticles are special in that their optical properties, in particular their colour, not only depend on the particles own properties but also on the properties of the particles immediate surrounding. This means that a plasmonic nanoparticle exhibit a slight colour change (= shift in the plasmon resonance wavelength) if molecules attach to its surface, a phenomenon that can be utilized for development of ultrasensitive biosensing methodologies focused at, for example, medical diagnostics. We have been doing nanoplasmonic biosensing experiments for many years and now want to push the methodology to the ultimate limit, that is to measure the colour shift of single nanoparticles induced by single bio(macro)molecules. We are also interested to use optical forces, so-called laser tweezers, to trap and manipulate single nanoparticles for different sensing experiments. We are currently setting up new dedicated microspectroscopy and laser tweezers systems with performance beyond state-of-the-art. The PhD project focuses on developing, evaluating and expanding the single molecule LSPR technique and/or optical tweezers technologies in the context of biomedical analysis.

Major responsibilities
The goal with a PhD-position is to develop general research proficiency and a high competence within your specific research area. As a PhD-student, you will primarily conduct research, often together with other researchers and PhD students. You will also follow PhD courses, be involved in teaching activities, and participate in international conferences and networks. You are expected to write a licentiate thesis within 2-3 years and defend your doctoral thesis within 4-5 years. The total time period for the position is limited to four years full time, or five years with 20% teaching load.

Position summary
Full-time temporary employment. The employment is composed of a maximum full-time four-year doctoral programme and a maximum one year of department duties, including teaching, equivalent to a maximum of 20 % of the total working time. The employment is thus limited to a total of five years. The employment is tied to successful progress of doctoral studies, evaluated at one and three years.

Qualifications
To qualify as a PhD student, you must have a master's degree in a relevant field such as MSc in chemistry, biochemistry, biophysics, physics, nanoscience or equivalent and a broad knowledge of biochemistry, physical chemistry and analytical chemistry. Excellent skills in writing and talking English is mandatory.

Meritorius educational qualifications are basic courses in physics, in particular optics. Experience in optical spectroscopy, optical microscopy, and clean room work and good knowledge in Swedish is an advantage.

Applicants who do not have English or a Scandinavian language as their mother tongue need to have passed an English language test, for example TOEFL 550 (paper-based)/TOEFL 213 (computer-based), prior to admission.

For more information and how to apply:

http://www.chalmers.se/en/about-chalmers/vacancies/?rmpage=job&rmjob=2674…


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