Bioinformatics Engineer

Posted on by Micaela Brun
Job ID: 2018-322
Job date: 2018-04-06
End Date:

Company : CRISPR Therapeutics 

Country :

Role : Technician 


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Job Description:
We are seeking a talented Bioinformatics Engineer to tackle challenging bioinformatics and computational biology problems and work collaboratively with research groups to build and maintain the tools, algorithms, and pipelines required to support the development of new, transformative CRISPR/Cas9-based gene editing therapies.

Responsibilities:

  • Balance evaluation, integration, and extension of existing bioinformatics and next generation sequencing (NGS) tools with the creation of new tools and algorithms as needed for varying project and problem contexts
  • Run analysis pipelines on data generated from novel CRISPR/Cas9 assays, and work with preclinical teams to deliver insights and recommendations to decision makers
  • Develop web tools for data analysis and integration in close interaction with biologists and with a strong focus on the researchers’ needs
  • Creatively troubleshoot issues, implement test cases, and fix bugs
  • Give accurate time estimates based on verbal and written specifications
  • Convert research prototype scripts into robust scientific software optimized for performance, scalability, and adherence to coding best practices
Minimum Qualifications :
  • Degree (B.S. with 2+ years of research experience or graduate degree) in quantitative or basic science (computational biology, bioinformatics, computer science, chemistry, physics, or mathematics preferred)
  • Ability to implement, debug, and maintain computational tools in common programming languages (Python, R, C++, and/or Java)
  • Experience in processing NGS data through bioinformatics pipelines and usage of common bioinformatics tools (e.g. BWA, BEDtools, GATK, IGV)
  • Proficiency with handling large-scale genomic data in a Linux and/or cloud environment (e.g. AWS)
  • Experience with version control software (e.g. Git)
  • Ability to work independently and successfully in a matrix environment, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively
  • Good communication skills including research report and paper writing, code documentation, and oral presentation
Preferred Qualifications:
  • Strong knowledge of Unix/Linux Operating Systems
  • Experience with DevOps tools (e.g. Docker, Jenkins, Puppet)
  • Experience writing automated functional and unit test scripts
  • Technical familiarity with database (e.g. MySQL, Oracle) design and query construction
  • Familiarity with molecular biology techniques, gene editing, and/or CRISPR/Cas9 biology
  • A high degree of energy, accuracy and attention to detail, and a passion for creating transformative gene-based medicines for patients with serious diseases
Competencies :
  • Approachability – Is easy to talk to, builds rapport well, and makes extra effort to put others at ease.
  • Listening – Practices active, patient listening. Has the ability to restate and consider a differing view, even when not in agreement.
  • Problem Solving – The ability to understand a situation, task or problem by breaking it down into smaller pieces using a systematic approach and to identify patterns and connections between situations that are not obviously related.
  • Creativity/Innovation - creating a boundary-less environment that fosters curiosity and taking risks, openness to new approaches, diversity of new thought, blank page creativity and opportunistic thinking.
  • Perseverance – Pursues tasks with energy, drive and initiative, even in the face of adversity.
  • Results Oriented – Drives issues to closure and gets the job done.
  • Communication and Teamwork – The ability to effectively express ideas in written and oral context. The ability to work co-operatively with others; the genuine desire to be a part of a team and contribute to organizational and team goals.

Requeriments :

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Additional Info:
If interested and qualified, please include Requisition # 2018-322 in the subject line when emailing resume to: careers@crisprtx.com .

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