Job ID: 7226BR
Job date: 2017-02-22
End Date:
Company : Illumina, Inc Country : Role : Research Scientist
Job date: 2017-02-22
End Date:
Company : Illumina, Inc Country : Role : Research Scientist
Job Description:
We are seeking an exceptional individual to join our team in developing analysis tools that will be used by researchers and clinicians worldwide. These tools will be incorporated in Illumina’s expanding oncology portfolio and used in high visibility projects such as the 100,000 Genomes Project. Responsibilities: -Creation of novel sequence analysis workflows (i.e. read alignment, variant calling, and variant annotation) to support both research and clinical products. -Design, prototype, and implement computational algorithms that utilize both statistical and machine learning approaches. -Software optimization at the design, algorithm, and source code level. -Identify opportunities to improve the bioinformatics user experience and implement solutions. -Collaborate with internal project teams and with external organizations. -Contribute to the bioinformatics open source community. Requirements: -Strong background in developing software with multiple languages and multiple platforms. Experience with C#, C++, Java, and Go is highly advantageous. -Personal initiative and ability to work effectively as part of a team. -Familiarity with applying statistical approaches to algorithm development. -Superior written and verbal communication skills. -Basic knowledge of genomics, genetics, and sequencing technologies. Preferences: -Familiarity with agile software development processes (e.g. scrum). -Hands-on experience with sequence analysis tools such as samtools and GATK. -Experience with sequencing data analysis. -Experience with cloud computing, parallel computing, and big data. -Familiarity with genomic annotation databases (e.g. RefSeq, Ensembl, dbSNP, DGV, dbVAR, ClinVar, COSMIC, and ExAC). -Experience with using version control systems such as git and TFS. Education: Master’s degree or PhD in bioinformatics, biology, engineering, physical sciences, computer science, mathematics, statistics, or equivalent.
Additional Info:
Why is one person more likely to develop a disease—like cancer, diabetes or Parkinson’s—than someone else? Why would one person respond differently to treatment than another? What is the most effective treatment for each patient? Illumina’s technologies are helping researchers and clinicians around the world to answer these questions and others, on a scale not even possible a few years ago. Our team specializes in developing tools and workflows to analyze somatic mutations found in tumor and normal tissue samples. One of the many challenges in this area involve analyzing archived FFPE samples that often present problematic sequence artifacts. We devise methods to counteract these sources of error and to continually expand the limits of detection for our tools. Our team is actively developing variant annotation tools that are both more accurate than existing tools, but also orders of magnitude faster. We aspire to bridge the gap between variant discovery and providing actionable information for research and clinical use. When you join the high-performing team at Illumina, your work takes on new meaning. Our growth, our positive culture, and the impact our products are having in the world ignite a passion that drives our people forward. And together, we accomplish beyond expectations. All About Us: Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as the global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture and other emerging segments. lllumina has experienced phenomenal growth from $10 million in revenues in 2002 to approximately $2.2 billion in 2015. Forbes named Illumina #1 on the 2009 list of 25 Fastest-Growing Technology Companies in the United States, the second time over a three year period that Forbes ranked Illumina #1 on its list of rapidly growing technology companies. Illumina was also named #1 smartest company in the world as part of MIT’s 2014 Technology Review. As of February 2016, the company had a $21 billion market capitalization. EOE / Minorities / Females / Veterans / Disabled EOE/Minorities/Females/Vet/Disability[Click Here to Access the Original Job Post]
We are seeking an exceptional individual to join our team in developing analysis tools that will be used by researchers and clinicians worldwide. These tools will be incorporated in Illumina’s expanding oncology portfolio and used in high visibility projects such as the 100,000 Genomes Project. Responsibilities: -Creation of novel sequence analysis workflows (i.e. read alignment, variant calling, and variant annotation) to support both research and clinical products. -Design, prototype, and implement computational algorithms that utilize both statistical and machine learning approaches. -Software optimization at the design, algorithm, and source code level. -Identify opportunities to improve the bioinformatics user experience and implement solutions. -Collaborate with internal project teams and with external organizations. -Contribute to the bioinformatics open source community. Requirements: -Strong background in developing software with multiple languages and multiple platforms. Experience with C#, C++, Java, and Go is highly advantageous. -Personal initiative and ability to work effectively as part of a team. -Familiarity with applying statistical approaches to algorithm development. -Superior written and verbal communication skills. -Basic knowledge of genomics, genetics, and sequencing technologies. Preferences: -Familiarity with agile software development processes (e.g. scrum). -Hands-on experience with sequence analysis tools such as samtools and GATK. -Experience with sequencing data analysis. -Experience with cloud computing, parallel computing, and big data. -Familiarity with genomic annotation databases (e.g. RefSeq, Ensembl, dbSNP, DGV, dbVAR, ClinVar, COSMIC, and ExAC). -Experience with using version control systems such as git and TFS. Education: Master’s degree or PhD in bioinformatics, biology, engineering, physical sciences, computer science, mathematics, statistics, or equivalent.
Requeriments :
- M.Sc. or higher Degree in Bioinformatics
- M.Sc. or higher Degree in Computer Science
- M.Sc. or higher Degree in Statistics
- Master's Degree in Engineering
Skills :
- Genetics
- genomic
- Machine Learning
- Next Generation Sequencing
- Parallel Computing
- Programing in C++
- Programming in C#
- Programming in Java
- Software Design
- Statistics
Areas :
Additional Info:
Why is one person more likely to develop a disease—like cancer, diabetes or Parkinson’s—than someone else? Why would one person respond differently to treatment than another? What is the most effective treatment for each patient? Illumina’s technologies are helping researchers and clinicians around the world to answer these questions and others, on a scale not even possible a few years ago. Our team specializes in developing tools and workflows to analyze somatic mutations found in tumor and normal tissue samples. One of the many challenges in this area involve analyzing archived FFPE samples that often present problematic sequence artifacts. We devise methods to counteract these sources of error and to continually expand the limits of detection for our tools. Our team is actively developing variant annotation tools that are both more accurate than existing tools, but also orders of magnitude faster. We aspire to bridge the gap between variant discovery and providing actionable information for research and clinical use. When you join the high-performing team at Illumina, your work takes on new meaning. Our growth, our positive culture, and the impact our products are having in the world ignite a passion that drives our people forward. And together, we accomplish beyond expectations. All About Us: Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as the global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture and other emerging segments. lllumina has experienced phenomenal growth from $10 million in revenues in 2002 to approximately $2.2 billion in 2015. Forbes named Illumina #1 on the 2009 list of 25 Fastest-Growing Technology Companies in the United States, the second time over a three year period that Forbes ranked Illumina #1 on its list of rapidly growing technology companies. Illumina was also named #1 smartest company in the world as part of MIT’s 2014 Technology Review. As of February 2016, the company had a $21 billion market capitalization. EOE / Minorities / Females / Veterans / Disabled EOE/Minorities/Females/Vet/Disability[Click Here to Access the Original Job Post]