Bioinformatics Scientist I

Job Description:
Support the development of new diagnostic products in a fast-pace R&D environment. Play an important role in building up data analysis capacities for microbiome projects, identifying and prioritizing biomarker candidates for various diseases, and assembling biological insights and crucial knowledge for decision making.

ESSENTIAL DUTIES AND RESPONSIBILITIES

• Develop or implement data analysis pipelines for microbiome projects.
• Carry out bioinformatics tasks such as sequence analysis, prediction of RNA secondary structures, design of primers and probes for qPCR, identification of toxin genes and antibiotic resistance gene cassettes, etc.
• Implement state of the art and develop novel methodologies of systems biology in support of developing new diagnostic products.
• Mine literature, public and proprietary databases for biomarker candidates and prioritize their importance based on pathway analysis and/or data integration.
• Analyze both clinical and experimental data for the development and the validation of multiplex biomarker panels.
• Integrate biomarker data of heterogeneous sources for biological and clinical insights.
• Develop various database to host data from diverse technical platforms.
• Other duties may be assigned.

QUALIFICATIONS/EDUCATION AND EXPERIENCE

• Ph.D. degree with 2 years (or MS degree with 5+ years) of working experience in industry in the field of systems biology, bioinformatics, computational biology, or equivalent.
• Solid computational skills and deep understanding of biochemistry, microbiology and/or molecular biology.
• Extensive experience in next-generation sequencing, systems biology and analysis of large scale OMICS datasets.
• Proficient in one statistical language (R, MatLab or SAS) AND one script language (such as PERL or Python).
• Experience in prediction of RNA secondary structures, sequence analysis, primer and probe design for qPCR, and identification of toxin genes and antibiotic resistance gene cassettes is preferred.
• Experience in the field of microbiome is preferred.
• Proficient in relational databases (SQL or Oracle) is a big plus.
• Experience in developing scripts for mining literature and public databases is a big plus.
• Excellent communication skills, including solid presentation and writing skills.

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Requeriments :

• M.Sc. or higher Degree in Bioinformatics
• M.Sc. or higher Degree in computational biology

Skills :

• Biochemistry
• Microbiology
• molecular biology
• Next Generation Sequencing
• Programing in Python
• Programming in Matlab
• Programming in PERL
• Programming in R
• Programming in SAS
• SQL
• Systems Biology

Areas :

• Bioinformatics

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Additional Info:

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