Job ID: 19884
Job date: 2017-01-18
End Date:
Company : The Rockefeller University Country : Role : Research Scientist
Job date: 2017-01-18
End Date:
Company : The Rockefeller University Country : Role : Research Scientist
Job Description:
Working closely with a team of molecular biologists, biochemists and behavior specialists, the Bioinformatics Specialist will collaborate and analyze data for those producing RNA and DNA sequencing data. Will perform sequence alignment, differential expression for RNA-seq, peak search for epigenomic data, pathway analysis, and various statistical analysis, potentially also combining with publically available human data both genomic and genetic. The Bioinformatics Specialist will work with senior lab members and provide tailored analysis that will best suit their project's needs. Will pursue unique research in the fields of systems biology, neurodegeneration (e.g. Alzheimer's disease and Parkinson's disease) and other brain related disorders such as major depression. Job Requirements: Master's degree required; Ph.D. preferred. Educational emphasis in bioinformatics preferred. Must have detailed knowledge of current bioinformatics tools, working knowledge of molecular biology (preferably neurobiology), and familiarity with gene expression data analysis, preferably with RNA-seq and/or ChIPseq data analysis. Proficiency in Linux scripting, programming skills in a major language, and ability to handle large datasets required. Excellent communication and interpersonal skills are necessary.
Additional Info:
The Laboratory of Molecular and Cellular Neuroscience studies the molecular defects responsible for neurological and psychiatric disorders including Alzheimer's disease, major depressive disorder, Parkinson's disease, and obsessive compulsive disorder, as well as the molecular mechanisms by which neuro- and psychoactive drugs produce their pharmacological actions in these disorders. Research from the laboratory has demonstrated that most neurotransmitters and neuromodulators achieve their actions and interactions on post-synaptic neurons through a process called "slow synaptic transmission." This process involves activation of highly complex signal transduction cascades. For the last 10 years, the group has applied this knowledge and developed a state-of-the-art methodologies (eg. BacTRAP), to the study of the molecular pathways behind various neurological and psychiatric disorders.[Click Here to Access the Original Job Post]
Working closely with a team of molecular biologists, biochemists and behavior specialists, the Bioinformatics Specialist will collaborate and analyze data for those producing RNA and DNA sequencing data. Will perform sequence alignment, differential expression for RNA-seq, peak search for epigenomic data, pathway analysis, and various statistical analysis, potentially also combining with publically available human data both genomic and genetic. The Bioinformatics Specialist will work with senior lab members and provide tailored analysis that will best suit their project's needs. Will pursue unique research in the fields of systems biology, neurodegeneration (e.g. Alzheimer's disease and Parkinson's disease) and other brain related disorders such as major depression. Job Requirements: Master's degree required; Ph.D. preferred. Educational emphasis in bioinformatics preferred. Must have detailed knowledge of current bioinformatics tools, working knowledge of molecular biology (preferably neurobiology), and familiarity with gene expression data analysis, preferably with RNA-seq and/or ChIPseq data analysis. Proficiency in Linux scripting, programming skills in a major language, and ability to handle large datasets required. Excellent communication and interpersonal skills are necessary.
Requeriments :
Skills :
- Bioinformatics
- DNA sequencing
- Genetics
- Lunix/Unix
- molecular biology
- Programing Skills
- RNA-seq
- Statistics
- Systems Biology
Areas :
Additional Info:
The Laboratory of Molecular and Cellular Neuroscience studies the molecular defects responsible for neurological and psychiatric disorders including Alzheimer's disease, major depressive disorder, Parkinson's disease, and obsessive compulsive disorder, as well as the molecular mechanisms by which neuro- and psychoactive drugs produce their pharmacological actions in these disorders. Research from the laboratory has demonstrated that most neurotransmitters and neuromodulators achieve their actions and interactions on post-synaptic neurons through a process called "slow synaptic transmission." This process involves activation of highly complex signal transduction cascades. For the last 10 years, the group has applied this knowledge and developed a state-of-the-art methodologies (eg. BacTRAP), to the study of the molecular pathways behind various neurological and psychiatric disorders.[Click Here to Access the Original Job Post]