Job ID: PI100741494
Job date: 2018-01-05
End Date:
Company : Foundation Medicine Country : Role : Research Scientist
Job date: 2018-01-05
End Date:
Company : Foundation Medicine Country : Role : Research Scientist
Job Description:
The Clinical Bioinformatics Scientist will be responsible for analysis and delivery of NGS sequence data in a high-complexity clinical diagnostic laboratory to clinicians, pharmaceutical partners, and academic collaborators. In addition, the position will be responsible for collecting and presenting quality metrics and reviewing variant reports. The successful candidate will possess a high level of professional maturity, an ability to consistently meet tight deadlines under pressure, exquisite attention to detail and an obsession with quality. Responsibilites:
Additional Info:
Job Location: Penzberg, Germany Overview: In 2015, Roche and Cambridge, MA-based Foundation Medicine announced a broad, strategic collaboration in the field of molecular information for oncology. The collaboration is a multi-part agreement that includes an R&D collaboration, a U.S. educational support collaboration, and an ex-U.S. commercial collaboration, among other aspects. Roche also invested $250 million into Foundation Medicine and, as part of a stock purchase, became a majority shareholder in Foundation Medicine. We believe this strategic collaboration accelerates and strengthens our respective leadership positions delivering molecular information solutions globally and advancing precision medicine in oncology. As part of the commercial collaboration, Foundation Medicine is building and plans to operate a molecular information, next generation sequencing facility in Penzberg, Germany. This laboratory will serve as Foundation Medicine's strategic hub for commercial growth in several countries in Europe. As such, Foundation Medicine is actively recruiting for the following positions at its Penzberg, Germany site: Foundation Medicine is dedicated to helping bring personalized cancer medicine into routine clinical practice. Harnessing advanced technology, Foundation Medicine is developing clinical laboratory tests that will broadly capture the most relevant tumor genomic and other molecular information in a single test, and connect it with relevant scientific and medical knowledge to help oncologists determine the right treatment for each patient. Note: This offering is not located within Roche Diagnostics GmbH or other Roche-entities. This position will be filled at Foundation Medicine, Inc. and FMI Germany GmbH. By submitting your application documents you acknowledge your personal data being transferred to Foundation Medicine, Inc. and FMI Germany GmbH in order to process your application. Contact: Dr. Thomas Wieland Mail: twieland@foundationmedicine.com PI100741494[Click Here to Access the Original Job Post]
The Clinical Bioinformatics Scientist will be responsible for analysis and delivery of NGS sequence data in a high-complexity clinical diagnostic laboratory to clinicians, pharmaceutical partners, and academic collaborators. In addition, the position will be responsible for collecting and presenting quality metrics and reviewing variant reports. The successful candidate will possess a high level of professional maturity, an ability to consistently meet tight deadlines under pressure, exquisite attention to detail and an obsession with quality. Responsibilites:
- Assume responsibility for developing annotated genomic profiles of somatic aberrations based on massively-parallel sequencing (NGS) data, in the context of studies of cancer-patient samples.
- Review genomic variant calls using proprietary and publicly available tools (e.g. IGV) in collaboration with the scientific team.
- Provide test results according to SOP with the best possible quality within defined turn-around times.
- Collaborate with technical teams in specifying requirements for tools to enhance workflow efficiency and robustness.
- Development, analysis and testing of advanced computational methods to enhance FM's clinical diagnostic platform with an emphasis on rigorously validated results and robust procedures to bring methods to the operational level.
- Delivery of novel biomarker signatures based on NGS to pharmaceutical partners and academic collaborators, with an emphasis on accuracy and timeliness.
- Development and validation of clinical diagnostic assays for pharmaceutical partners based on massively parallel sequencing (NGS) data.
- Assisting with drafting and completing manuscripts for publication; manage data analysis and interpretation of study results throughout manuscript publication process from draft through submission and acceptance.
- MS in Bioinformatics.
- Experience with bioinformatics tools and databases (NCBI, UCSC Genome Browser, IGV).
- Working knowledge of cancer genetics and experience with Next-Generation Sequencing (NGS).
- Scripting ability in Python or Perl.
- Familiar with UNIX environment and use of clusters to parallelize the execution of computational methods.
- Strong organizational skills in order to maintain a high level of productivity, innovation and setting priorities in order to complete assignments in a timely manner.
- Fluency in English is required
Requeriments :
Skills :
- Bioinformatics
- Bioinformatics Databases
- Genetics
- Lunix/Unix
- Next Generation Sequencing
- Programing in Python
- Programming in PERL
Areas :
Additional Info:
Job Location: Penzberg, Germany Overview: In 2015, Roche and Cambridge, MA-based Foundation Medicine announced a broad, strategic collaboration in the field of molecular information for oncology. The collaboration is a multi-part agreement that includes an R&D collaboration, a U.S. educational support collaboration, and an ex-U.S. commercial collaboration, among other aspects. Roche also invested $250 million into Foundation Medicine and, as part of a stock purchase, became a majority shareholder in Foundation Medicine. We believe this strategic collaboration accelerates and strengthens our respective leadership positions delivering molecular information solutions globally and advancing precision medicine in oncology. As part of the commercial collaboration, Foundation Medicine is building and plans to operate a molecular information, next generation sequencing facility in Penzberg, Germany. This laboratory will serve as Foundation Medicine's strategic hub for commercial growth in several countries in Europe. As such, Foundation Medicine is actively recruiting for the following positions at its Penzberg, Germany site: Foundation Medicine is dedicated to helping bring personalized cancer medicine into routine clinical practice. Harnessing advanced technology, Foundation Medicine is developing clinical laboratory tests that will broadly capture the most relevant tumor genomic and other molecular information in a single test, and connect it with relevant scientific and medical knowledge to help oncologists determine the right treatment for each patient. Note: This offering is not located within Roche Diagnostics GmbH or other Roche-entities. This position will be filled at Foundation Medicine, Inc. and FMI Germany GmbH. By submitting your application documents you acknowledge your personal data being transferred to Foundation Medicine, Inc. and FMI Germany GmbH in order to process your application. Contact: Dr. Thomas Wieland Mail: twieland@foundationmedicine.com PI100741494[Click Here to Access the Original Job Post]