Computational Biologist/Bioinformatician

Job ID:
Job date: 2018-04-18
End Date: 2018-06-17

Company : Howard Hughes Medical Institute 

Country : United States 

Role : Other 


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Job Description:
We are seeking a talented, highly motivated individual with a background in Computational Biology/Bioinformatics to join the laboratory headed by Professor Frederick Alt in the Program in Cellular and Molecular Medicine (PCMM), Department of Genetics at Harvard Medical School, Boston. The Alt lab is world-renown for its research on genome instability and antibody maturation. The lab continues to develop and apply cutting-edge high-throughput techniques to address challenging questions regarding mechanisms of rearrangements in the 3D genome and on mechanisms underlying the generation and affinity maturation of antibody repertoires.

Candidates should have either a Master or PhD degree in a relevant quantitative science field (bioinformatics, computational science, physical science, etc.). A successful candidate should have experience in the analysis of large-scale “omic” data sets, particularly NGS data sets. Candidates also should have experience working on Linux-type servers and with programming languages (e.g. Python, Perl, R, etc.). A basic knowledge of statistics and biology is required. The position offers an opportunity to work with an engaged group of scientists and participate in research combining genomics and immunogenomics datasets. The ideal Ph.D. candidate will have a record of scientific rigor and creativity, a strong publication record in peer-reviewed scientific journals and the ability to work in teams. Excellent oral and written communication skills are required.

Summary of Responsibilities:

  • Lead in the development of new methods and algorithms/pipelines to analyze novel high-throughput sequencing techniques developed by the lab.
  • Lead in the analysis of next-generation sequencing data of immunogenomics, genomes, epigenomes, and transcriptomes derived from experimental specimens.
  • Implement new analytical tools to analyze “omic” data.
  • Work closely with laboratory scientists to analyze NGS data, provide expert consultation
  • Work in teams with other scientists to prepare publications and research documentation


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Additional Info:
Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world. Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit hhmi.org/careers to learn more about working at HHMI.

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