Job ID: 620547
Job date: 2017-07-28
End Date:
Company : Charite - Universitatsmedizin Berlin Country : Role : Other
Job date: 2017-07-28
End Date:
Company : Charite - Universitatsmedizin Berlin Country : Role : Other
Job Description:
The Charité Center 17 for Gynecology, Perinatal, Pediatric and Juvenile Medicine with Perinatal Center and Human Genetics, Department of Pediatric Oncology and Hematology of the Charité Berlin is seeking a Computational Biologist / Bioinformatician We are looking for a computational biologist / bioinformatician to develop and apply new analytical approaches for the study of neuroblastoma genomics. This research position is integrated into the two research consortia SYSMED-NB (funded by the BMBF) and the CRG04 TERMINATE-NB (funded by the Berlin Institute of Health (BIH)) and is embedded into an interdisciplinary team of clinicians, biologists, biotechnologists and bioinformaticians and into the dynamic intellectual environment of the Charité and the BIH. The successful applicant will 1) set up analytical pipelines for diagnostic targeted resequencing, 2) plan and perform analyses within neuroblastoma research projects, 3) structure and manage high-throughput data 4) support existing collaborations with other bioinformatics groups (e.g. Nils Blüthgen, Uwe Ohler, Altuna Akalin, Dieter Beule). In collaboration with these groups, the applicant will be able to pursue his/her own bioinformatics research projects. Prerequisites of the candidate: The ideal candidate has a Master's (MSc) or PhD degree in computer science, computational biology, bioinformatics, statistics or any other quantitative discipline and proven experience in the analysis of next-generation sequencing data. Moreover, the candidate should have excellent programming skills for data analysis, preferably in R, and be familiar with Bash scripting and one other scripting language such as Perl/Python. In-depth knowledge of applied multivariate statistics and data visualization techniques are also required. An advanced knowledge of tumor biology and a publication track record of genomics-based oncology research are highly desirable. Excellent communication and project management skills as well as the motivation for a long-time commitment in our department are a requirement.
Additional Info:
The Charité is one of the largest university hospitals in Europe. All of our clinical care, research and teaching is delivered by physicians and researchers of the highest international standard. Charité proudly lays claim to more than half of all German Nobel Prize winners in Physiology or Medicine, including Emil von Behring, Robert Koch, and Paul Ehrlich. Charité is internationally renowned for its excellence in teaching and training. Charité – Universitätsmedizin Berlin represents a single medical faculty, which serves both Humboldt Universtität zu Berlin and Freie Universität Berlin. Charité extends over four campuses, and has close to 100 different Departments and Institutes, which make up a total of 17 different Charité Centers. Having marked its 300-year anniversary in 2010, Charité is now one of the largest employers in Berlin, employing 13,100 staff (or 16,800 if including its subsidiaries), and with a total annual turnover of €1.5 billion The Pediatric Oncology Reseach Institute of the Department of Pediatric Hematology, Oncology and SCT (Director: Prof. Dr. A. Eggert) at the Charité – University Medicine Berlin is a recently founded multidisciplinary research institute closely affiliated to the Helmholtz Institute, Max Delbrück Center (MDC) for Molecular Medicine and the Berlin Institute of Health (BIH). The main focus of all research programs is to improve cure rates of malignant childhood diseases by combining basic, translational and clinical research. The goals of the research group of Prof. Dr. Johannes H. Schulte are improved understanding of tumor biology and development of new therapeutic options for neuroblastoma, a highly devastating childhood cancer. Investigating primary and relapse tumors as well as tumor model systems, we seek to identify key factors of tumor pathogenesis, tumor progression and tumor evolution. Of special interest is the role of epigenetics and non-coding RNAs in these processes. The research strategy of our interdisciplinary team includes multi-omics and wet lab approaches. Concepts identified in high-throughput analyses are validated in vitro and in vivo. To this end, we use cell culture model systems, patient-derived tumor xenografts and genetically engineered mouse models. Furthermore, we participate in major European Systems Biology Consortia for generating and analyzing high-throughput sequencing data. Job conditions: The job is open from 1st of August 2017. Salary will be according to the Charité internal tariff TV-C E13 with regular working time of 39 h per week. The initial contract will be until 31st of July, 2019 with the option of extension depending on extramural funding resources. The Charité – Universitätsmedizin Berlin is an equal opportunity employer and supports gender equality. Persons with disabilities will be preferred if equally qualified. The Charité cannot reimburse any incurring travel expenses. Please, submit your application by email, including all documents (cover letter describing your interests, CV, and 2-3 letters of recommendation) by August 13, 2017, to Prof. Johannes Schulte and Dr. Jörn Tödling at the Charité Children's Hospital (johannes.schulte@charite.de and joern.toedling@charite.de) and indicate the registration number, DM.127.17. Please do not exceed a file size of 5MB and supply documents as pdfs. Please be advised that we cannot return any paper documents.[Click Here to Access the Original Job Post]
The Charité Center 17 for Gynecology, Perinatal, Pediatric and Juvenile Medicine with Perinatal Center and Human Genetics, Department of Pediatric Oncology and Hematology of the Charité Berlin is seeking a Computational Biologist / Bioinformatician We are looking for a computational biologist / bioinformatician to develop and apply new analytical approaches for the study of neuroblastoma genomics. This research position is integrated into the two research consortia SYSMED-NB (funded by the BMBF) and the CRG04 TERMINATE-NB (funded by the Berlin Institute of Health (BIH)) and is embedded into an interdisciplinary team of clinicians, biologists, biotechnologists and bioinformaticians and into the dynamic intellectual environment of the Charité and the BIH. The successful applicant will 1) set up analytical pipelines for diagnostic targeted resequencing, 2) plan and perform analyses within neuroblastoma research projects, 3) structure and manage high-throughput data 4) support existing collaborations with other bioinformatics groups (e.g. Nils Blüthgen, Uwe Ohler, Altuna Akalin, Dieter Beule). In collaboration with these groups, the applicant will be able to pursue his/her own bioinformatics research projects. Prerequisites of the candidate: The ideal candidate has a Master's (MSc) or PhD degree in computer science, computational biology, bioinformatics, statistics or any other quantitative discipline and proven experience in the analysis of next-generation sequencing data. Moreover, the candidate should have excellent programming skills for data analysis, preferably in R, and be familiar with Bash scripting and one other scripting language such as Perl/Python. In-depth knowledge of applied multivariate statistics and data visualization techniques are also required. An advanced knowledge of tumor biology and a publication track record of genomics-based oncology research are highly desirable. Excellent communication and project management skills as well as the motivation for a long-time commitment in our department are a requirement.
Requeriments :
- M.Sc. or higher Degree in Bioinformatics
- M.Sc. or higher Degree in computational biology
- M.Sc. or higher Degree in Computer Science
- M.Sc. or higher Degree in Statistics
Skills :
- Biology
- Cancer Genomics
- Next Generation Sequencing
- Programing in Python
- Programing Skills
- Programming in PERL
- Programming in R
- Statistics
Areas :
Additional Info:
The Charité is one of the largest university hospitals in Europe. All of our clinical care, research and teaching is delivered by physicians and researchers of the highest international standard. Charité proudly lays claim to more than half of all German Nobel Prize winners in Physiology or Medicine, including Emil von Behring, Robert Koch, and Paul Ehrlich. Charité is internationally renowned for its excellence in teaching and training. Charité – Universitätsmedizin Berlin represents a single medical faculty, which serves both Humboldt Universtität zu Berlin and Freie Universität Berlin. Charité extends over four campuses, and has close to 100 different Departments and Institutes, which make up a total of 17 different Charité Centers. Having marked its 300-year anniversary in 2010, Charité is now one of the largest employers in Berlin, employing 13,100 staff (or 16,800 if including its subsidiaries), and with a total annual turnover of €1.5 billion The Pediatric Oncology Reseach Institute of the Department of Pediatric Hematology, Oncology and SCT (Director: Prof. Dr. A. Eggert) at the Charité – University Medicine Berlin is a recently founded multidisciplinary research institute closely affiliated to the Helmholtz Institute, Max Delbrück Center (MDC) for Molecular Medicine and the Berlin Institute of Health (BIH). The main focus of all research programs is to improve cure rates of malignant childhood diseases by combining basic, translational and clinical research. The goals of the research group of Prof. Dr. Johannes H. Schulte are improved understanding of tumor biology and development of new therapeutic options for neuroblastoma, a highly devastating childhood cancer. Investigating primary and relapse tumors as well as tumor model systems, we seek to identify key factors of tumor pathogenesis, tumor progression and tumor evolution. Of special interest is the role of epigenetics and non-coding RNAs in these processes. The research strategy of our interdisciplinary team includes multi-omics and wet lab approaches. Concepts identified in high-throughput analyses are validated in vitro and in vivo. To this end, we use cell culture model systems, patient-derived tumor xenografts and genetically engineered mouse models. Furthermore, we participate in major European Systems Biology Consortia for generating and analyzing high-throughput sequencing data. Job conditions: The job is open from 1st of August 2017. Salary will be according to the Charité internal tariff TV-C E13 with regular working time of 39 h per week. The initial contract will be until 31st of July, 2019 with the option of extension depending on extramural funding resources. The Charité – Universitätsmedizin Berlin is an equal opportunity employer and supports gender equality. Persons with disabilities will be preferred if equally qualified. The Charité cannot reimburse any incurring travel expenses. Please, submit your application by email, including all documents (cover letter describing your interests, CV, and 2-3 letters of recommendation) by August 13, 2017, to Prof. Johannes Schulte and Dr. Jörn Tödling at the Charité Children's Hospital (johannes.schulte@charite.de and joern.toedling@charite.de) and indicate the registration number, DM.127.17. Please do not exceed a file size of 5MB and supply documents as pdfs. Please be advised that we cannot return any paper documents.[Click Here to Access the Original Job Post]