Machine Learning/Biological systems modeling

Job ID:
Job date: 2018-03-17
End Date:

Company : Finch Therapeutics 

Country :

Role : Other 


[Click Here to Access the Original Job Post]

Job Description:
We are searching for passionate teammates eager to support this mission.

As a member of our Data Science team, your mission is to develop tools and intuition to predict successful microbial therapies. You will design and implement statistical learning and modeling tools, and new feature construction methodology, to extract biological meaning from low-sample high-feature microbial data from human clinical samples. You will further our microbial drug development platform by mining microbial datasets, developing our machine learning platform, and working closely with both bench scientists and clinicians to brainstorm and test functional hypotheses about microbial community dynamics, pathology, and therapy.

Responsibilities will include but are not limited to:

  • Adapt machine learning and statistical modeling techniques to low sample, heterogenous data types to effectively identify microbial drivers of pathology and therapy.
  • Propose new biological hypotheses for microbial drivers of host phenotype, based on high throughput molecular data, design in silico and in vitro tests of these hypotheses.
  • Use machine learning effectively and develop new analysis strategies for large biological datasets (e.g. 16S, metagenomics)
  • Work closely with bench scientists to design and analyze microbial function and phenotype experiments
  • Work with clinicians to help design and analyze clinical trials (particularly of microbial therapeutics)
  • Communicate analysis results with a variety of audiences including clinicians, bench scientists, industry executives, and academic researchers, especially with effective graphical output.
  • Work effectively as part of a multifunctional team in support of a commercially viable therapeutics discovery platform
Qualifications:
  • PhD in computational biology, computer engineering, statistics, or related field
  • Expert in machine learning and statistical modeling, especially of biological systems, exemplified by a record of innovating in this field.
  • Proven ability to utilize feature construction and data transformations to uncover signal in biological datasets
  • Demonstrated ability to innovate with wide data (features > samples)
  • Facility with big data visualization, especially with R or python matplotlib
  • Ability to work independently
  • Eager to work collaboratively in a team and to both give and receive feedback to support professional development for self and others
  • Ability to perform complex analyses in a time sensitive fashion
  • Strong organizational and communications skills
Additional Desired Skills & Experience (not required):
  • Experience with microbial ecology or evolution, metagenomics, genomics or GWAS
  • Familiarity with cloud computing, in particular AWS EC2, CFN
  • Expertise in immunology
  • Previous experience developing database architecture


Requeriments :

Skills :

Areas :


Additional Info:
About Finch Therapeutics :

Finch Therapeutics is unlocking the therapeutic potential of the microbiome via our human-first drug discovery platform. We support clinical studies that intentionally manipulate the microbiome to investigate causality in diseases that are otherwise poorly understood, then leverage this clinical data to focus our in vitro and in vivo efforts on cocktails of microbes that have already demonstrated safety and efficacy in humans. Using high-throughput molecular data these human and ex-vivo experiments, we identify specific strains that drive clinical phenotypes and responses to microbial therapies. Our team values transparency, integrity, humility, and collaboration, and we intend to have fun while maximizing our ability to make an impact on patients’ lives.

At Finch Therapeutics, you can expect to engage deeply in the core of our mission. You will grow with a dynamic, rapidly expanding organization, and have an opportunity to contribute to cutting edge research that will truly impact patients’ lives. We offer a competitive starting salary, plus healthcare and other benefits. As we grow, there will be opportunities for promotion and professional development.

This is a full-time, exempt position with a comprehensive benefits package.

This is an entry-level position, reporting to the Director of Data Science.

Application Instructions:

The start date for this position is flexible. To apply, please go to http://finchtherapeutics.com/jobs to submit your cover letter and resume. Promising candidates will be contacted to further evaluate their fit for this role and our organization.

Authorization to work in the US is required. No visa sponsorship is possible.

[Click Here to Access the Original Job Post]