Post Doctoral Fellow – “computational genomics/systems biology”

Job ID: 8295
Job date: 2017-12-26
End Date:

Company : St. Jude Children's Research Hospital 

Country :

Role : Postdoc 


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Job Description:
A postdoctoral fellow position is open in the Tan research group in the Departments of Pediatrics and Biomedical and Health Informatics (DBHI) at the Children’s Hospital of Philadelphia (CHOP) http://tanlab4generegulation.org. Dr. Tan is an associate professor of Pediatrics and Biomedical and Health Informatics.

CHOP postdoctoral fellows receive mentored training in a rich scientific environment that includes both CHOP and University of Pennsylvania research communities. CHOP is an interdisciplinary institution dedicated to conducting basic, clinical and translational research with a particular focus on conditions that affect children.

The candidate will work on developing computational algorithms for cancer regulatory genomics and epigenomics. Specific projects in these two laboratories will be defined by the candidate (and based on the candidates expertise) and with input from Dr. Tan and our close collaborators at the Center for Childhood Cancer Research CHOP and Abramson Cancer Center at the University of Pennsylvania.

The desired candidate must have a terminal degree (PhD) in computational biology, computer science, statistics, mathematics or related field with a strong understanding of biology. The postdoctoral fellow will be responsible for development of novel computational algorithms and integrative analysis of high-dimensional datasets, focused on generating insights into how mutations in regulatory DNA sequences contribute to oncogenesis. The postdoc experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the research group. Postdocs will be expected to participate in project planning, bioinformatics recording and interpretation/evaluation of data, and communication of results.

Postdoctoral fellows will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. Postdoctoral fellows also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

Required Education and Experience:

The postdoctoral fellow (postdoc) will have a terminal degree PhD, MD, DVM, etc. and will, under the direction/guidance of a mentor (principal investigator), assume responsibility for a specific, on-going research project. The postdoc experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group.

Postdocs will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results. Postdocs will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. Postdoctoral fellows also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing.

EDUCATION AND EXPERIENCE:

•PhD in computational biology, computational science, statistics, or mathematics, engineering, genomics/genetics or related fields

•UNIX/LINUX and high performance computing experience

•Exhibited knowledge of statistics and probability important to bioinformatics research

•Proficiency in R or similar commonly used statistical languages

•Basic proficiency with Python, Perl, or other languages

•Strong understanding of cancer molecular biology and genetics

•Exhibited knowledge of biological network analysis

•Values research integrity and collaborative research

•Strong research skills

•Effective problem solving/critical thinking skills

•Ability to work independently and with a strong work ethic

•High level of motivation

•Excellent communication/interpersonal skills

•Ability to exercise discretion and judgment

SKILLS AND ABILITIES:

  • Strong research skills
  • Effective problem solving/critical thinking skills
  • Ability to work independently
  • Ability to exercise discretion and judgment
  • Value for research integrity and collaborative research
  • High level of motivation
  • Good communication skills
  • Strong interpersonal skills


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Additional Info:
The Tan research group is interdisciplinary and highly collaborative, utilizing both computational and experimental approaches to study gene regulation. We have pioneered multiple computational algorithms for regulatory genomics, epigenomics, and network biology.

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans. Please contact our hiring official with any referrals or questions.

CHOP Careers Contact

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146

Phone: 866-820-9288

Email:TalentAcquisition@email.chop.edu

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