Job ID: 5237
Job date: 2016-03-11
End Date:
Company : Moderna Therapeutics Inc. Country : Role : Research Scientist
Job date: 2016-03-11
End Date:
Company : Moderna Therapeutics Inc. Country : Role : Research Scientist
Job Description:
Valera, a Moderna venture, is seeking an exceptionally talented and highly motivated Computational Biologist with a broad skill base to work as part of a highly collaborative, multi-disciplinary, and fast-paced team. Valera’s mission is to develop mRNA vaccines and therapeutics for infectious diseases. The successful applicant will deploy his/her extensive expertise in protein modelling to develop novel antigens or therapeutics proteins that can be successfully encoded via Moderna’s technology
Responsibilities
* Using computational biology tools, structural data and/or relevant homologous-protein models, design and/or optimize antigens to elicit the desired immunological responses for novel vaccines, working closely with protein engineering and immunology colleagues
* Using computational biology tools, structural data and/or relevant homology models, design and/or optimize novel protein therapeutics/antibodies to elicit the desired PK/PD, once expressed via Moderna’s mRNA technology
* Mine relevant publicly available and commercial protein and nucleotide sequence databases
* Develop and apply new computational biology methods and data processing to further enhance the ability to design antigens/proteins
* Serve as a technical expert in computational biology within the organization and provide support to multiple projects and programs
* Identify, manage and contribute to external collaborations relevant to computational biology
* Communicate findings internally and externally
Minimum Qualifications
* Ph.D. with 3+ years of experience or M.S. with 6+ years of experience in Computational Biology or related field
* Technical proficiency required in:
- State of the art chemical biology tools and methods
- Commonly used commercial and open source software packages
- High performance computing in a distributed/cloud environment, e.g. AWS
* Proven ability to draw robust conclusions from complex datasets, and present them in a clear and understandable way
* An established record of innovative research achievements in bioinformatics reported in top-tier journals and patent applications
* Strong written and oral communication skills, comfort with senior management interactions
* Positive team building and teamwork skills: innate ability to influence, lead and inspire people, within function and beyond functional/company boundaries
Preferred Qualifications
* Experience of antigen design and optimization for the development of vaccines
* Experience of protein/antibody engineering
* Strong foundation in molecular biology
* The ideal candidate will have deep scientific and technical expertise in the following:
- Protein Structure Modeling and Analysis
- Sequence searching, alignment, and analysis
- Motif discovery, sequence mining
- Biological databases of sequence and functional data, e.g. pdb, EMBL, GenBank, Entrez, UniProt, RefSeq, miRBase, ENCODE, Roadmap, etc.
Competencies
* Commitment to excellence and innovation
* Flexibility; adaptability to frequent change
* Scientific rigor
* Self-starter with a “can do” attitude
* Results oriented; ability to manage performance
* Effective communication, both written and verbal
* Personal and shared accountability
* Scientific and people leadership skills Job Information Position Type: Scientist Start Date: ASAP Duration: Full Time Status: openContact InformationModerna Therapeutics
Valera
http://www.modernatx.com How To Apply:visit the online job posting at Modernatx.com:
https://modernatx.wd1.myworkdayjobs.com/en-US/M_tx/job/320-Bent-Street---Cambridge---USA---MA/Scientist-Sr-Scientist--Computational-Biology_R0000030
Additional Info:
[Click Here to Access the Original Job Post]
ISCB Job Board
Scientist/Sr. Scientist, Computational BiologyModerna TherapeuticsValeraUSA-MA-Cambridge Position SummaryValera, a Moderna venture, is seeking an exceptionally talented and highly motivated Computational Biologist with a broad skill base to work as part of a highly collaborative, multi-disciplinary, and fast-paced team. Valera’s mission is to develop mRNA vaccines and therapeutics for infectious diseases. The successful applicant will deploy his/her extensive expertise in protein modelling to develop novel antigens or therapeutics proteins that can be successfully encoded via Moderna’s technology
Responsibilities
* Using computational biology tools, structural data and/or relevant homologous-protein models, design and/or optimize antigens to elicit the desired immunological responses for novel vaccines, working closely with protein engineering and immunology colleagues
* Using computational biology tools, structural data and/or relevant homology models, design and/or optimize novel protein therapeutics/antibodies to elicit the desired PK/PD, once expressed via Moderna’s mRNA technology
* Mine relevant publicly available and commercial protein and nucleotide sequence databases
* Develop and apply new computational biology methods and data processing to further enhance the ability to design antigens/proteins
* Serve as a technical expert in computational biology within the organization and provide support to multiple projects and programs
* Identify, manage and contribute to external collaborations relevant to computational biology
* Communicate findings internally and externally
Minimum Qualifications
* Ph.D. with 3+ years of experience or M.S. with 6+ years of experience in Computational Biology or related field
* Technical proficiency required in:
- State of the art chemical biology tools and methods
- Commonly used commercial and open source software packages
- High performance computing in a distributed/cloud environment, e.g. AWS
* Proven ability to draw robust conclusions from complex datasets, and present them in a clear and understandable way
* An established record of innovative research achievements in bioinformatics reported in top-tier journals and patent applications
* Strong written and oral communication skills, comfort with senior management interactions
* Positive team building and teamwork skills: innate ability to influence, lead and inspire people, within function and beyond functional/company boundaries
Preferred Qualifications
* Experience of antigen design and optimization for the development of vaccines
* Experience of protein/antibody engineering
* Strong foundation in molecular biology
* The ideal candidate will have deep scientific and technical expertise in the following:
- Protein Structure Modeling and Analysis
- Sequence searching, alignment, and analysis
- Motif discovery, sequence mining
- Biological databases of sequence and functional data, e.g. pdb, EMBL, GenBank, Entrez, UniProt, RefSeq, miRBase, ENCODE, Roadmap, etc.
Competencies
* Commitment to excellence and innovation
* Flexibility; adaptability to frequent change
* Scientific rigor
* Self-starter with a “can do” attitude
* Results oriented; ability to manage performance
* Effective communication, both written and verbal
* Personal and shared accountability
* Scientific and people leadership skills Job Information Position Type: Scientist Start Date: ASAP Duration: Full Time Status: openContact InformationModerna Therapeutics
Valera
http://www.modernatx.com How To Apply:visit the online job posting at Modernatx.com:
https://modernatx.wd1.myworkdayjobs.com/en-US/M_tx/job/320-Bent-Street---Cambridge---USA---MA/Scientist-Sr-Scientist--Computational-Biology_R0000030
Requeriments :
Skills :
Areas :
Additional Info:
[Click Here to Access the Original Job Post]