Job Description:
We are seeking a talented and motivated computational biologist/bioinformatician with expertise in biomarker discovery to join our research team. The successful candidate will contribute to target validation, biomarker discovery, and mechanism-of-action studies. Demonstrated expertise in modern data analysis techniques applied to -omics technologies is a critical component of the successful applicant. Other aspects of the role include technology innovation and implementation of analytical methodologies for the characterization of discovery-stage therapeutic candidates. Education: MS or PhD in Bioinformatics, Computational Biology, Computer Science, or Systems Biology with 3 - 5 years of relevant experience in an academic or industry setting (new PhD grads are encouraged to apply) Qualifications:
Additional Info:
$110,000 - $140,000 a year Company Overview Trovagene is a precision medicine biotechnology company developing oncology therapeutics for improved cancer care by leveraging our proprietary Precision Cancer Monitoring® (PCM) technology and experience in tumor genomics. Our broad intellectual property and proprietary technology allow us to measure circulating tumor DNA (ctDNA) in urine and blood to identify and quantify clinically actionable markers for predicting patient response to cancer therapies. We offer our PCM technology at our CLIA/CAP-accredited laboratory and plan to continue to vertically integrate our PCM technology with the development of precision cancer therapeutics. We believe our ctDNA PCM technology and expertise in liquid biopsy testing provides a unique advantage for the development of precision cancer therapeutics.[Click Here to Access the Original Job Post]
We are seeking a talented and motivated computational biologist/bioinformatician with expertise in biomarker discovery to join our research team. The successful candidate will contribute to target validation, biomarker discovery, and mechanism-of-action studies. Demonstrated expertise in modern data analysis techniques applied to -omics technologies is a critical component of the successful applicant. Other aspects of the role include technology innovation and implementation of analytical methodologies for the characterization of discovery-stage therapeutic candidates. Education: MS or PhD in Bioinformatics, Computational Biology, Computer Science, or Systems Biology with 3 - 5 years of relevant experience in an academic or industry setting (new PhD grads are encouraged to apply) Qualifications:
- Background in developing and implementing pipelines for analyzing high-throughput “omics” datasets (such as genomics, transcriptomics or proteomics)
- Pre-clinical or clinical theauraputic development experience is desirable
- Experience with oncology biomarker discovery highly desirable
- Demonstrated experience in data curation, data mining and an ability to interrogate, interpret, and visualize large genomic datasets
- Identifies molecular features from genomics datasets that correlate with clinical outcomes.
- Previous analysis experience with short read NGS data, variant detection methods, variant annotation and QC metrics.
- Proficiency with a high-level scripting language (e.g. Python, R, Perl) required Experience working in linux and cloud environments (AWS preferred)
- Strong background in implementing statistical learning methods (e.g. regularized regression, PCA, logistic regression, classification techniques, clustering etc.)
- Strong background in standard inferential statistics, including, robust techniques and survival modeling
- Prior experience working with large-scale genetics and genomics datasets (Big Data)
- Familiarity and experience with NCBI, RefSeq, Ensembl, TCGA, Cosmic, UCSC, ClinVar, DECIPHER, ENCODE, 1000 Genomes
Requeriments :
- M.Sc. or higher Degree in Bioinformatics
- M.Sc. or higher Degree in computational biology
- M.Sc. or higher Degree in Computer Science
Skills :
- Biomarker Discovery
- Data Mining
- Genetics
- genomic
- Lunix/Unix
- Modeling
- Next Generation Sequencing
- Programing in Python
- Programming in PERL
- Programming in R
- Statistics
Areas :
Additional Info:
$110,000 - $140,000 a year Company Overview Trovagene is a precision medicine biotechnology company developing oncology therapeutics for improved cancer care by leveraging our proprietary Precision Cancer Monitoring® (PCM) technology and experience in tumor genomics. Our broad intellectual property and proprietary technology allow us to measure circulating tumor DNA (ctDNA) in urine and blood to identify and quantify clinically actionable markers for predicting patient response to cancer therapies. We offer our PCM technology at our CLIA/CAP-accredited laboratory and plan to continue to vertically integrate our PCM technology with the development of precision cancer therapeutics. We believe our ctDNA PCM technology and expertise in liquid biopsy testing provides a unique advantage for the development of precision cancer therapeutics.[Click Here to Access the Original Job Post]