Job ID: 254958094
Job date: 2016-12-29
End Date:
Company : Intrexon Corporation Country : Role : Research Scientist
Job date: 2016-12-29
End Date:
Company : Intrexon Corporation Country : Role : Research Scientist
Job Description:
The Senior BioInformatics Scientist – NGS Data Analysis (level determined by candidate experience) will develop complex analysis pipelines in areas such as genome assembly, RNA-seq and expression analysis, metabolomics, proteomics, and variant analysis. Work will span areas that include microbial and yeast work through Human health and agricultural biotechnology. This individual will help connect bench scientists with existing internal systems by developing new interfaces, analyses, and methods. Candidates must have experience developing robust software and dealing with deployment, versioning, and system maintenance issues. There will be opportunity to innovate with both data processing infrastructure and analytic method development. Ability to interpret the data into specific, actionable tasks, and tie results back to biological outcomes and literature will be well used. Knowledge of foundational biological principles is necessary, and background in microbial physiology and/or yeast genomics is strongly desired. Knowledge in other areas such as Human health, genome editing, and agricultural biotechnology may also be useful. The exact level of this position and development vs scientific focus will be determined based on the candidate. DUTIES AND RESPONSIBILITIES: -Collaborate to integrate sequencing and other omics analyses with existing database applications, sample handling workflow, and analysis infrastructure. -Analyze and interpret resulting omics data, relevant literature, associated data such as fermentation results, and communicate results clearly to biologists. Help design new experiments as needed. -Develop analysis pipelines for genomic and RNA-Seq data from Next-Generation Sequencing experiments. -Annotate and analyze genomes and generate biological hypotheses. -Develop and/or adopt omics integration and machine learning techniques. EDUCATION AND EXPERIENCE: -PhD, MS or equivalent experience in Computer Science, Molecular Biology or a related discipline. -Minimum of three (3)+ years experience and strong interdisciplinary background and ability to interact collaboratively with bench scientists. -Experience in pipeline development and one or more of genome assembly, rna-seq analysis, variant analysis, metabolomics, proteomics. -Strong Python software development skills. -Experience with REST APIs a plus. -Knowledge of databases (SQL, noSQL, graph etc.) and database design needed, Oracle DB experience desired. -Experience in high-throughput data analysis, visualization (ActivityBase, Spotfire, Tableau, R, etc.) and interpretation. -Experience with Javascript, CSS, and at least one web development framework desired. -Algorithm development experience, basic knowledge of statistics required. -Experience with machine learning, statistical method development is a plus. -Functional knowledge of biological principles including gene structure, gene regulation, and functional annotation. -Knowledge of CRISPR, TALEN, and other modern genome editing technologies is a plus. DESIRED KEY COMPETENCIES: -Ability to understand and execute on the company’s mission and values. -Maintain a high degree of ethical standard and trustworthiness. -Capable of fostering change in an organization. -Deals with conflict in a direct, positive manner. -Ability to think and adapt to a rapidly changing environment. -Able to reach rational conclusions through complex processing of information. -Fosters innovation through creative solutions. -Successful at communicating in both oral and written forms. -Fosters constructive dialogue and feelings toward the company, coworkers, and tasks being managed. -Well organized and capable of clear communication through technology (i.e. Outlook, PowerPoint, and other programs used to create and distribute reports and key information). -Effective organization and implementation of group projects. -Up-to-date knowledge on industry current events. -Maintain a high degree of accuracy and attention to detail. -Energized by accomplishments and excellence in the workplace. -Capable of high performance in independent work as well as in team setting.
Additional Info:
Intrexon Corporation (NYSE: XON) is Powering the Bioindustrial Revolution with Better DNA™ to create biologically-based products that improve the quality of life and the health of the planet. The Company’s integrated technology suite provides its partners across diverse markets with industrial-scale design and development of complex biological systems delivering unprecedented control, quality, function, and performance of living cells. We call our synthetic biology approach Better DNA®, and we invite you to discover more at www.dna.com or follow @Intrexon on Twitter.[Click Here to Access the Original Job Post]
The Senior BioInformatics Scientist – NGS Data Analysis (level determined by candidate experience) will develop complex analysis pipelines in areas such as genome assembly, RNA-seq and expression analysis, metabolomics, proteomics, and variant analysis. Work will span areas that include microbial and yeast work through Human health and agricultural biotechnology. This individual will help connect bench scientists with existing internal systems by developing new interfaces, analyses, and methods. Candidates must have experience developing robust software and dealing with deployment, versioning, and system maintenance issues. There will be opportunity to innovate with both data processing infrastructure and analytic method development. Ability to interpret the data into specific, actionable tasks, and tie results back to biological outcomes and literature will be well used. Knowledge of foundational biological principles is necessary, and background in microbial physiology and/or yeast genomics is strongly desired. Knowledge in other areas such as Human health, genome editing, and agricultural biotechnology may also be useful. The exact level of this position and development vs scientific focus will be determined based on the candidate. DUTIES AND RESPONSIBILITIES: -Collaborate to integrate sequencing and other omics analyses with existing database applications, sample handling workflow, and analysis infrastructure. -Analyze and interpret resulting omics data, relevant literature, associated data such as fermentation results, and communicate results clearly to biologists. Help design new experiments as needed. -Develop analysis pipelines for genomic and RNA-Seq data from Next-Generation Sequencing experiments. -Annotate and analyze genomes and generate biological hypotheses. -Develop and/or adopt omics integration and machine learning techniques. EDUCATION AND EXPERIENCE: -PhD, MS or equivalent experience in Computer Science, Molecular Biology or a related discipline. -Minimum of three (3)+ years experience and strong interdisciplinary background and ability to interact collaboratively with bench scientists. -Experience in pipeline development and one or more of genome assembly, rna-seq analysis, variant analysis, metabolomics, proteomics. -Strong Python software development skills. -Experience with REST APIs a plus. -Knowledge of databases (SQL, noSQL, graph etc.) and database design needed, Oracle DB experience desired. -Experience in high-throughput data analysis, visualization (ActivityBase, Spotfire, Tableau, R, etc.) and interpretation. -Experience with Javascript, CSS, and at least one web development framework desired. -Algorithm development experience, basic knowledge of statistics required. -Experience with machine learning, statistical method development is a plus. -Functional knowledge of biological principles including gene structure, gene regulation, and functional annotation. -Knowledge of CRISPR, TALEN, and other modern genome editing technologies is a plus. DESIRED KEY COMPETENCIES: -Ability to understand and execute on the company’s mission and values. -Maintain a high degree of ethical standard and trustworthiness. -Capable of fostering change in an organization. -Deals with conflict in a direct, positive manner. -Ability to think and adapt to a rapidly changing environment. -Able to reach rational conclusions through complex processing of information. -Fosters innovation through creative solutions. -Successful at communicating in both oral and written forms. -Fosters constructive dialogue and feelings toward the company, coworkers, and tasks being managed. -Well organized and capable of clear communication through technology (i.e. Outlook, PowerPoint, and other programs used to create and distribute reports and key information). -Effective organization and implementation of group projects. -Up-to-date knowledge on industry current events. -Maintain a high degree of accuracy and attention to detail. -Energized by accomplishments and excellence in the workplace. -Capable of high performance in independent work as well as in team setting.
Requeriments :
Skills :
- Biology
- Database design
- Genome Assembly
- genomic
- JavaScript
- Machine Learning
- Microbial Biology
- Next Generation Sequencing
- NoSQL
- Programing in Python
- RNA-seq
- Software Design
- SQL
- Statistics
Areas :
Additional Info:
Intrexon Corporation (NYSE: XON) is Powering the Bioindustrial Revolution with Better DNA™ to create biologically-based products that improve the quality of life and the health of the planet. The Company’s integrated technology suite provides its partners across diverse markets with industrial-scale design and development of complex biological systems delivering unprecedented control, quality, function, and performance of living cells. We call our synthetic biology approach Better DNA®, and we invite you to discover more at www.dna.com or follow @Intrexon on Twitter.[Click Here to Access the Original Job Post]