Senior Staff Scientist – Computational Biology – Host Microbiota Interactions : Cambridge, United Kingdom

Job ID: 627455
Job date: 2017-10-23
End Date:

Company : Wellcome Trust Sanger Institute 

Country :

Role : Research Scientist 


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Job Description:
We are seeking a talented, motivated and experienced computational biologist at the Wellcome Trust Sanger Institute, under the leadership of Dr Trevor Lawley. We are looking for an enthusiastic and skilled bioinformatician or computational biologist, to join the Host-Microbiota Interactions Lab (www.lawleylab.com). This is an exciting opportunity for the successful candidate to join a dynamic team investigating the role of the microbiota in human health and a variety of diseases, such as autoimmunity, infections and cancers, using genomics, microbiology and model organisms. There is a strong translational focus to the Lab with the goal of developing novel, microbiome based diagnostics and therapeutics.

The successful applicant will have expertise in the large-scale analyses of next-generation sequencing data to investigate the microbial communities contained on and within host organisms that are associated with health and disease. They will be part of a multidisciplinary, collaborative team and will be expected to work closely with existing team members to accomplish scientific objectives and proactively identify, establish and develop new collaborations and new projects.

You will have substantial opportunities for learning and development, working closely with informaticians, wet-lab biologists, Postdoctoral Fellows and PhD students across the Infection Genomics Programme.

Essential Skills:

• A Masters or PhD in Bioinformatics, Genomics, Microbiology (or similar)

• Demonstrated experience in programming/scripting using Python or Perl

• Proficiency in Linux/Unix operating systems

• Experience in next generation sequencing and the analysis of sequencing data

• Excellent communication, organisational and problem-solving skills.

• Team player with ability to effectively prioritise, multi-task and work independently

• Ability to review, synthesise, and present scientific data and methods. Good writing and verbal communication skills.

• Enthusiasm, commitment and attention to detail

Ideal Skills:

• Demonstrated track record of analysing and interpreting large datasets and delivering complex scientific projects through to publication.

• Knowledge of metagenomics and microbiota analysis

• Strong understanding of Microbial Genomics and Phylogeny

• Broad knowledge of functional or metabolic analysis of microbial genomes

• Experience in the use and/or design of relational databases (e.g. MySQL)

• Detailed knowledge of statistical and/or machine learning methods appropriate for biological research

• Demonstrated experience in software development, documentation and code management


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Additional Info:
The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.

Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application.

Closing date for applications: 19th November 2017 , however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.

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