Job Description:
Senior Scientist in Computational Biology Siemens Healthcare Laboratory R&D Berkeley, CA This Senior Scientist in Computational Biology will report to the Head of R&D and Technology for the Siemens Healthcare Laboratory in Berkeley, CA. The Computational Biologist will be primarily responsible for designing, implementing and validating new and improved data analysis pipelines for Next Generation Sequencing. Additional responsibilities include development of data and statistical analysis methods for studies of molecular tests and immunoassays in the context of selection or monitoring of patients treated with targeted therapies. The position is within Siemens Healthcare Laboratory R&D, which provides our pharmaceutical industry partners and molecular services customers with decades of institutional expertise in development and implementation of diagnostic assays. Computational Biology is a core capability that enables the effective use of our tests for research, as clinical trial assays, and as Laboratory Developed Tests. The successful candidate will support a broad range of project teams, coordinate activities with colleagues at other Siemens R&D sites, and may oversee the work of several other Siemens data scientists or contractors. Responsibilities:
Additional Info:
Division Description: Siemens is a global technology powerhouse that has stood for engineering excellence, innovation, quality, reliability and internationality for more than 165 years. As a global technology company, Siemens is rigorously leveraging the advantages that this setup provides. To tap business opportunities in both new and established markets, the Company is organized in nine Divisions: Power and Gas, Wind Power and Renewables, Energy Management, Building Technologies, Mobility, Digital Factory, Process Industries and Drives, Healthineers and Financial Services. With 45,000 employees Siemens Healthineers is one of the world’s largest suppliers of technology to the healthcare industry and a leader in medical imaging, laboratory diagnostics and healthcare IT. All supported by a comprehensive portfolio of clinical consulting, training, and services available across the globe and tailored to customers’ needs. So that more people can have a life that is longer, richer, and more filled with happiness. For more information, please visit: http://www.usa.siemens.com/healthineers Equal Employment Opportunity Statement : Siemens is an Equal Opportunity and Affirmative Action Employer encouraging diversity in the workplace. All qualified applicants will receive consideration for employment without regard to their race, color, creed, religion, national origin, citizenship status, ancestry, sex, age, physical or mental disability, marital status, family responsibilities, pregnancy, genetic information, sexual orientation, gender expression, gender identity, transgender, sex stereotyping, protected veteran or military status, and other categories protected by federal, state or local law. EEO is the Law : Applicants and employees are protected under Federal law from discrimination. Pay Transparency Non-Discrimination Provision : Siemens follows Executive Order 11246, including the Pay Transparency Nondiscrimination Provision[Click Here to Access the Original Job Post]
Senior Scientist in Computational Biology Siemens Healthcare Laboratory R&D Berkeley, CA This Senior Scientist in Computational Biology will report to the Head of R&D and Technology for the Siemens Healthcare Laboratory in Berkeley, CA. The Computational Biologist will be primarily responsible for designing, implementing and validating new and improved data analysis pipelines for Next Generation Sequencing. Additional responsibilities include development of data and statistical analysis methods for studies of molecular tests and immunoassays in the context of selection or monitoring of patients treated with targeted therapies. The position is within Siemens Healthcare Laboratory R&D, which provides our pharmaceutical industry partners and molecular services customers with decades of institutional expertise in development and implementation of diagnostic assays. Computational Biology is a core capability that enables the effective use of our tests for research, as clinical trial assays, and as Laboratory Developed Tests. The successful candidate will support a broad range of project teams, coordinate activities with colleagues at other Siemens R&D sites, and may oversee the work of several other Siemens data scientists or contractors. Responsibilities:
- Implementation and maintenance of data analysis pipelines and analytical tools that enable comprehensive genetic tumor profiling
- Development and improvement of algorithms to identify chromosomal copy number changes and other actionable genomic alterations in tumor DNA derived from clinical specimens such as FFPE, fresh frozen tissue or blood samples
- Processing and interpretation of large data sets generated by our NGS teams, including development and implementation of analytical tools for troubleshooting
- Development of methods and software tools to support large-scale bioinformatics analysis
- Documentation and testing of newly developed algorithms
- MS or PhD in Computational Biology, Bioinformatics, Computer Science, or other related scientific disciplines is expected, although a BS with extensive work experience may be considered
- Experience in NGS data processing and evaluation
- Experience with bioinformatics tools and databases
- Knowledge of cancer genetics and biology
- Knowledge of programming and scripting languages such as R, C++ and Python
- Effective English skills both verbal and written
- Ability to work in a team
- Experience in working with regulated software is a plus
- Additional knowledge of molecular virology, immunology, cardiovascular disease, neurology, or other medical fields of application for advanced computational biology methods
- Additional expertise in applications of biostatistics related to evaluation and selection of biomarkers for companion diagnostics development
Requeriments :
- M.Sc. or higher Degree in Bioinformatics
- M.Sc. or higher Degree in computational biology
- M.Sc. or higher Degree in Computer Science
- Technical Bachelor
Skills :
- Bioinformatics
- Bioinformatics Databases
- Biology
- Biomarker Discovery
- Biostatistics
- Cancer biology
- Computational Biology
- Genetics
- immunology
- Next Generation Sequencing
- Programing in C++
- Programing in Python
- Programing Skills
- Programming in R
- Statistics
Areas :
Additional Info:
Division Description: Siemens is a global technology powerhouse that has stood for engineering excellence, innovation, quality, reliability and internationality for more than 165 years. As a global technology company, Siemens is rigorously leveraging the advantages that this setup provides. To tap business opportunities in both new and established markets, the Company is organized in nine Divisions: Power and Gas, Wind Power and Renewables, Energy Management, Building Technologies, Mobility, Digital Factory, Process Industries and Drives, Healthineers and Financial Services. With 45,000 employees Siemens Healthineers is one of the world’s largest suppliers of technology to the healthcare industry and a leader in medical imaging, laboratory diagnostics and healthcare IT. All supported by a comprehensive portfolio of clinical consulting, training, and services available across the globe and tailored to customers’ needs. So that more people can have a life that is longer, richer, and more filled with happiness. For more information, please visit: http://www.usa.siemens.com/healthineers Equal Employment Opportunity Statement : Siemens is an Equal Opportunity and Affirmative Action Employer encouraging diversity in the workplace. All qualified applicants will receive consideration for employment without regard to their race, color, creed, religion, national origin, citizenship status, ancestry, sex, age, physical or mental disability, marital status, family responsibilities, pregnancy, genetic information, sexual orientation, gender expression, gender identity, transgender, sex stereotyping, protected veteran or military status, and other categories protected by federal, state or local law. EEO is the Law : Applicants and employees are protected under Federal law from discrimination. Pay Transparency Non-Discrimination Provision : Siemens follows Executive Order 11246, including the Pay Transparency Nondiscrimination Provision[Click Here to Access the Original Job Post]