Job Company: Medical Research Council

You will be working within the Statistics and Bioinformatics department primarily fulfilling a research support role, which will involve carrying out bioinformatics analyses of large data sets from human, vector and pathogen population genetics studies. You will be developing applications that apply state of the art algorithms to relevant data sets and contributing to publications, grant writing, experimental design, power and sample size calculations.  [More]

Postdoctoral Scientist – Bioinformatics MRC Toxicology Unit, Leicester Fixed Term for 5 years Salary £28,935 - £32,648 The Medical Research Council Toxicology Unit, (currently located at the University of Leicester but relocating to the University of Cambridge in 2018), is an internationally renowned institution focussed on the delivery of field-changing mechanistic insights into toxicology and disease.  We are equipped with state-of-the-art facilities and provide a supportive and learning environment helping postdoctoral scientists to establish themselves as successful research scientists in their chosen field.  Applications are invited for a postdoctoral scientist/bioinformatician to carry out detailed bioinformatics analysis on large data sets generated from proteomic and transcriptomic studies on localised RNA binding proteins. You will join the post transcriptional control group, led by Professor Anne Willis to work on a project funded by a joint Wellcome Trust Investigator award to Professor Anne Willis and Professor Kathryn Lilley University of Cambridge.  The project is entitled “Transcription, Trafficking, Translation: dissecting the spatiotemporal mechanisms underlying localised protein synthesis”. It is now widely acknowledged that mRNA is spatially organised such that its translation frequently occurs in the vicinity where the corresponding protein product adopts its function.  This phenomenon has been studied extensively in specialised cells, however, recent research has suggested that spatial restriction of mRNA storage and translation is much more widespread. The aims of this project are to define where translation of mRNA takes place in the cell, how this is regulated by protein binding partners and sequence motifs and how this changes upon cellular perturbation. For more information please visit: http://tox.mrc.ac.uk/research/willis-group/  [More]

Postdoctoral Scientist (TOX 133) Leicester Fixed-Term 3 years Salary Range:  £28,935 - £29,863 (plus allowances)  The research will focus on understanding mitochondrial signalling mechanisms involved in cell fate decisions. This project presents an ideal opportunity to learn a range of state-of the-art techniques, including, bioinformatics workflows, advanced brain imaging techniques, respirometry and behavioural assays.  You will be involved in design/conduct of experimental work, data collection, analysis and interpretation. You will be keeping accurate records of conducted research and will contribute to the research of the group as a whole.  [More]

Salary £28,648 - £30,486 per annum

We are looking to appoint a postdoctoral scientist to join the scientific group led by Professor Gerry Melino working on cancer biology with a particular focus on the p53-family. The project will concentrate on high throughput genomics to identify the main alterations in the genomic networks associated to p53 family-dependent metastasis and chemo-resistance phenotypes. For more information see http://tox.mrc.ac.uk/research/melino-group/ [More]

Postdoctoral Bioinformatics Scientist (Vaccinology Theme) £27000 - £32000 Fixed Term to 31st Dec 2015 with a subject to a probationary period of 6 months. [More]

We have an opportunity for an experienced Scientific Programmer / Researcher to fill the role of Data Management and Analysis Scientist integrating OCTOPUS instrument data and analysis software and hardware. [More]