Job Company: Wellcome Trust Sanger Institute
An exciting post-doctoral role is available within this multi-disciplinary team to work on a large-scale systems vaccinology study of rotavirus vaccine response. Rotavirus is the major cause of acute gastroenteritis in children under the age of five. In developed countries rotavirus vaccines are highly effective and have greatly reduced morbidity. However, in developing countries vaccine efficacy is significantly lower, despite minimal geographical variation in the circulating strains. [More]
The Wellcome Trust Sanger Institute are seeking to recruit a Senior Bioinformatician who can facilitate the scientific work of the Jones group by leading the computational data analysis support for the team and their collaborators.The group, led by Phil Jones, studies pre-cancer, how mutant cells evolve into cancers in humans and model systems We are interested in how mutant clones compete with each other and interact with the cancer promoting environment during epithelial cancer evolution in order to guide new cancer prevention therapy. [More]
We are looking for a senior C software developer to work on samtools, one of the world's most popular bioinformatics software packages. Our research in DNA and genetics produces a huge volume of data which produces many technical challenges in efficient processing and interpretation. By joining us you will help samtools meet these requirements. [More]
Two postdoctoral positions are available at the Wellcome Trust Sanger Institute (WTSI) under the leadership of Dr Peter Campbell. This is an exciting opportunity for the successful candidate to apply novel bioinformatic algorithms to unravel the mutational signatures that will hopefully explain the major global differences in cancer incidence, to understand the biological mechanisms underlying cancer-causing mutational processes and to explore their application towards surveillance of mutagenic exposures in human populations. [More]
In the Sanger Institute Malaria Programme, we are generating large scale genomic and transcriptomic data and we are looking for driven individuals to join our analysis team. Our new initiative will generate thousands of parasite and mosquito genomes each year from around the globe. To make the most of these data, we want to implement additional technological (e.g., long read sequencing, single cell sequencing) and analytical (e.g., machine learning, variation graphs) advances. [More]
The Wellcome Trust Sanger Institute is seeking a highly motivated researcher with strong skills in computational genomics to fill a postdoctoral fellow position. The aim of the fellow is to develop a quantitative framework for predicting antimicrobial resistance spread in clinical bacterial isolates from diverse generated large-scale genetic and phenotypic data. [More]
The primary goal of this position is to be involved in the Open Targets funded study of human neuronal cultures derived from patients with familial Alzheimer’s disease (AD) mutations using single-cell RNA-seq (scRNA-seq). The main goal is to characterize and compare different cell-types for mutants and controls to identify the pathways that result in early onset AD. [More]
The Wellcome Trust/Cancer Research UK Gurdon Institute, a leading cancer and developmental biology research institute with a vibrant computational environment, is seeking two people to join the Core Bioinformatics group, supporting research throughout the Institute.The persons appointed will have a PhD or equivalent in a scientific, computational or mathematical subject. Applicants with a scientific background are expected to demonstrate a solid understanding of molecular biology and experience of computational techniques used in the analysis of biological data. [More]
We are looking for a dynamic and motivated Postdoctoral Fellow to join the Hemberg Faculty Team and undertake research into neurobiology and bioinformatics. The successful candidate will be expected to contribute to the formulation and submission of research publications and research proposals as well as help manage and direct this complex and challenging project, as opportunities allow. [More]
An exciting opportunity has become available for a software developer/senior software developer to join the New Pipelines Group (NPG).The NPG group is a part of core sequencing informatics team at Wellcome Trust Sanger Institute. The group develops and maintains software for analysis and archival of sequencing and genotyping data produced by the high throughput facilities at the institute. [More]