Delivered high-quality internal machine learning tools and customer-facing data science solutions with the data science engineering teams.... From Endgame - 10 May 2016 20:35:52 GMT - View all jobs [More]

Originally posted on 2016-05-10

Knowledge of common Bioinformatics representations such as FASTA and HELM along with Bioinformatics storage solutions will also be considered.... From Dassault Systèmes - 13 May 2016 01:52:47 GMT - View all Remote jobs [More]

Originally posted on 2016-05-13

Cures  Start Here.   At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. The laboratory of Dr. Harlan Robins, Head of Computational Biology, is recruiting two postdoc positions funded by Stand UP 2 Cancer and the V Foundation to study the interaction between the adaptive immune system and cancer. This position will come with a competitive postdoc-level salary with great benefits for a two-year position with some possibility of extension. Fred Hutchinson Cancer Research Center, home of about 190 faculty including three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research. The environment is lively yet casual, with a strong emphasis on collaborative work. The Center is housed in a lovely campus next to Lake Union a short walk from downtown, and a slightly longer walk from the University of Washington. The position will involve technology development, algorithm creation, and applications. Primary research goals will be to develop high-throughput technologies to assess the specific immune response to cancer and to learn how the tumor evades this response and how the response can be resuscitated to effectively fight tumors.  [More]

Originally posted on 2016-05-07

Careers Start Here. A highly motivated post-doctoral research fellow is sought to carry out a research project in the lab of Dr. Andrew Hsieh at Fred Hutchinson Cancer Research Center in Seattle, WA. Applicants should be interested in the application of basic science and RNA biology research towards clinically intractable problems faced by cancer patients and will be expected to be scientifically intrepid. About the Hsieh Lab The primary focus of the Hsieh lab (http://research.fhcrc.org/hsieh/en.html) is to unravel the post-transcriptional mechanisms that govern the genesis and progression of epithelial malignancies. Our research seeks to understand how rogue cells co-opt the critical structure-function relationship between RNA and the protein synthesis machinery to drive specific cancer behavior at a molecular, cellular, and organismal level (Hsieh et al. Cancer Cell 2010, Hsieh et al. Nature 2012, Hsieh et al. Science Signaling 2015). We achieve this through utilizing cutting sequencing techniques and novel primary cell and animal models. Ultimately, we aim to utilize our fundamental discoveries in transnational control biology to tackle critical issues faced by cancer patients today. To be considered, candidates must have: A recent PhD, MD/PhD, or MD in a relevant biological field A strong background in RNA biology Experience with molecular and cellular biology techniques A demonstrated track record of productive research, with at least one first author paper Experience with bioinformatics is highly desirable An ability to work both independently and as part of a laboratory team Pay, Benefits, & Work Schedule: Full time position Salary DOE + excellent benefits To Apply: Please apply with a letter summarizing previous work experience, future research interests, and contact information for three professional references. If interested, please apply online via the  [More]

Originally posted on 2016-05-10

Scientists of the Philipps-Universität Marburg and the Max Planck Institute for Terrestrial Microbiology are researching at the LOEWE-Center for Synthetic Microbiology (SYNMIKRO) in 35 research groups in the fields of Biology, Chemistry, Pharmacy, Medicine, Physics as well as Mathematics, Computer Sciences and Ethics. Supported by the state of Hesse within its excellence program LOEWE, the interdisciplinary SYN-MIKRO-Center started its work in 2010. Today, SYNMIKRO is one of the largest centers of Synthetic Microbiological research worldwide.   As part of a collaborative project of SYNMIKRO together with the Department of Bioinformatics and Systems Biology of the Justus-Liebig Universität Gießen and embedded into the ERASynBio funded project “ECFexpress: An orthogonal, organism-independent expression platform based on extracytoplasmic function (ECF) sigma factors” we are seeking for a full-time   Research Assistant   Salary and benefits are according to a public service position in Germany (TV-H E 13). The Position starts as soon as possible and is limited until July 31, 2018. It is a position in a third-party funded research project, the limitation of which is not pursuant to § 2 Abs. 1 Wissenschaftszeitvertragsgesetz (WissZeitVG). Within the scope of the assigned duties it will offer the possibility of independent scientific research which can be used for further qualification. A limitation up to the period which is adequate to the duration of the qualification period as defined in § 2 Abs. 1 Satz 3 WissZeitVG cannot be assured.   Within this international project with partners from the USA, UK and Austria you will be responsible for the development of software for processing and visualization of bulk RNA-Seq data including the corresponding metadata. Enhanced analysis methods and adequate data structures must be developed for storage and integration of the analysis results and metadata, in order to enable comparison and combined analysis of diverse data sets. In addition, user-friendly visualization methods are required which allow interactive and intuitive exploration of data including the representation of regulatory networks.   The position is part of a bioinformatics sub-project with a focus on the analysis of high-throughput data (next generation sequencing, especially RNA-Seq and derivates) and their interpretation and visualization in a systems biology context. The further development of software infrastructure for data management is another important field of activity. Specific support of data analysis for the sub-project is expected as well as the development of new software tools and algorithms for the analysis and interpretation of high-throughput data from the Microbiology Department.  [More]

Originally posted on 2016-05-10

Recognized as a world leader of genomic research in pediatric cancer, the Computational Biology department at St. Jude Children’s Research Hospital (SJCRH) is currently seeking exceptional and creative scientists for multiple POSTDOCTORAL RESEARCH ASSOCIATE positions in the lab of Dr. Jinghui Zhang (www.stjude.org/zhang) to develop and apply innovative analytical and visualization approaches for studying the genome and epigenome of pediatric cancer. The fellows will have access to a wealth of resources including high-quality data, a state-of-art high-performance computing facility, robust analytical pipelines, the latest laboratory technology and research expertise in genomics, cancer biology, mathematics and computer science. The fellows will lead or participate in all aspects of cancer omics studies via multi-disciplinary teamwork and have opportunities to interact with leaders of pediatric cancer and translational research within and outside the institution. For those with ambitious career goals including those with no prior computing experience, inter-disciplinary training will be provided to broaden or strengthen computational or biological expertise.  Job # 34109 is immediately available to join our scientific visualization team to design and implement novel features and to expand the data content for our pediatric cancer genomic data portal initiative (https://pecan.stjude.org/proteinpaint/).   Job # 35345 is immediately available to further ongoing research in developing clonal evolution models of pediatric cancer based on the analysis of next-generation sequencing data.   Job # 35262 is immediately available to work as part of the NIH-funded Precision Medicine Center established in collaboration with the departments of Pharmaceutical Sciences and Pathology. The fellow will interact with the genomic discovery and visualization team to receive training and contribute new insight in these two areas.  For the complete job descriptions and to apply please click on the ''Apply through website'' button and look for the relevant Job ID.  [More]

Originally posted on 2016-05-11

The Institute for Biomedical Engineering – Cell Biology at RWTH Aachen University Medical School is offering a position for a Bioinformatic Scientist (PhD Student or Postdoc; m/f) starting as soon as possible. We offer a position, which is initially limited for 2 years with the option for extension. The salary is based on the German public service salary scale (TV-L). We are analyzing mechanisms of cellular differentiation in various types of stem cells – particularly embryonic stem cells, induced pluripotent stem cells, hematopoetic stem cells, mesenchymal stem cells, and dendritic cells. To this end, we are using own and public datasets that were generated by next generation sequencing (e.g. DNA-Seq, Chip-Seq, RNA-Seq) or microarrays (gene expression arrays and DNA-methylation platforms). The position is for a talented and motivated bioinformatics scientist that interacts closely with Wet-lab scientists of the groups of Prof. Martin Zenke (http://www.molcell.rwth-aachen.de) and Prof. Wolfgang Wagner (www.stemcellbiology.ukaachen.de). Particular focus is on epigenetic changes – e.g. histone modifications or DNA-methylation changes during differentiation, disease and aging. The lab will also validate and address bioinformatics hypotheses by genome editing technologies, such as CRISPR/Cas. Furthermore, bioinformatics research will be performed in collaboration with our colleagues at the IZKF Research Group Computational Biology (Dr. Ivan Costa; http://costalab.org) and the Joined Research Center for Computational Biomedicine at RWTH Aachen University (Professors Andreas Schuppert and Julio Saez-Rodriguez; www.combine.rwth-aachen.de) – thus, there is an excellent environment for your research.  [More]

Originally posted on 2016-05-12
2016-05-13  -  Bioimage Informatics Scientist  -    -  

Use cutting-edge microscopy and collaborate with the world’s brightest minds to help conduct groundbreaking research and find cures for children around the world. Bring your expertise in image processing, computer vision, machine learning and imagery data to design novel algorithms to assist St. Jude scientists in the analysis of microscopy imagery and understand vital biological processes to advance pediatric cancer research.   Your expertise will play a critical role in understanding brain development and pathophysiological basis of brain tumors and finding cures for children.   As part of a team of world-renowned scientist dedicated to finding cures, the Bioimage Informatics Scientist will be responsible to:    •Perform computational image analysis using extant software packages and custom-designed algorithms to quantitate and visualize biologically relevant metrics.   •Collaborate with an external software development team in the Oak Ridge National Laboratory Imaging, Signals and Machine Learning R&D to design machine-learning based computational approaches to meet needs of rapidly evolving research.   •Curate, store, update, and share bioimaging analysis software packages or custom developed algorithms.   •Serve as liaison with St. Jude Computational Biology and Information Sciences Departments to facilitate the efforts in these areas.   •Train and support user-directed operation of computational tools when necessary.   [More]

Originally posted on 2016-05-13

Competitive: Lilly: Eli Lilly and Company is seeking a talented bioinformatics scientist to join the Oncology Bioinformatics team. He or she will work in a dynamic cross Indianapolis, New York  [More]

Originally posted on 2016-05-13
2016-05-09  -  Screening Scientist  -    -  

University of Dundee - UK National Phenotypic Screening CentreSalary: Not specified [More]

Originally posted on 2016-05-08